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ClassicMendel

This is the official distribution of the legacy Mendel package, version 16.0.

Mendel is a comprehensive package for the statistical analysis of qualitative and quantitative genetic traits. See below for the anaylsis options available.

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Documentation

Mendel_16_Doc.pdf

Analysis options

MULTIPOINT_MAPPING          =  1 (Mapping Markers)
LOCATION_SCORES             =  2 (Location Scores)
CREATE_HAPLOTYPES           =  3 (Pedigree Haplotyping)
COMPUTE_SHARING_STATISTICS  =  4 (NPL)
FIND_GENOTYPING_ERRORS      =  5 (Mistyping)
ESTIMATE_ALLELE_FREQUENCIES =  6 (Allele Frequencies)
GENETIC_COUNSELING          =  7 (Risk Prediction)
GAMETE_COMPETITION_MODEL    =  8 (Gamete Competition)
PATERNITY_OR_GRAPH_TESTING  =  9 (Pedigree Selection)
COMPUTE_KINSHIP_MATRIX      = 10 (Kinship)
TEST_GENETIC_EQUILIBRIUM    = 11 (Genetic Equilibrium)
TEST_CASES_AND_CONTROLS     = 12 (Association by Permutation)
TRANSMISSION_DISEQUILIBRIUM = 13 (TDT)
ESTIMATE_PENETRANCES        = 14 (Penetrances)
ETHNIC_ADMIXTURE            = 15 (Ethnic Admixture)
COMBINE_ALLELES             = 16 (Combining Alleles)
GENE_DROPPING               = 17 (Gene Dropping)
COMBINE_LOCI                = 18 (Combining Loci)
POLYGENIC_QTL               = 19 (Variance Components)
QTL_ASSOCIATION             = 20 (QTL Association)
TRIM_PEDIGREES              = 21 (Trim Pedigrees)
ASSOCIATION_GIVEN_LINKAGE   = 22 (Association Given Linkage)
SNP_IMPUTATION              = 23 (SNP Imputation)
SNP_ASSOCIATION             = 24 (GWAS)
FILE_CONVERSION             = 25 (File Conversion)
MFGI                        = 26 (MFG)
INBRED_STRAINS              = 27 (Inbred Strains)
SIMULATE_TRAITS             = 28 (Simulate Traits)
PED_GWAS                    = 29 (Ped GWAS)
QMFG_LRT                    = 30 (QMFG LRT)
QMFG_SCORE                  = 31 (QMFG Score)

Citation

For publications please cite the following reference:

Lange K, Papp JC, Sinsheimer JS, Sripracha R, Zhou H, Sobel EM. Mendel: the Swiss army knife of genetic analysis programs. Bioinformatics. 2013 Jun 15;29(12):1568-70. doi: 10.1093/bioinformatics/btt187. Epub 2013 Apr 22. PMID: 23610370; PMCID: PMC3673222.

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