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Racemic synthesis of 4-(5-(2-(3,4-difluorophenyl)-2-hydroxyethoxy)-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)benzonitrile #178

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alintheopen opened this issue Apr 14, 2014 · 3 comments
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Racemic synthesis of 4-(5-(2-(3,4-difluorophenyl)-2-hydroxyethoxy)-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)benzonitrile #178

alintheopen opened this issue Apr 14, 2014 · 3 comments
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Being Synthesised Now Series 4

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This compound is being synthesised as part of the Series 4 Triazolopyrazine amides (see wiki http://openwetware.org/wiki/OpenSourceMalaria:Triazolopyrazine_%28TP%29_Series).

ELN entries are here:

InChI=1S/C20H13F2N5O2/c21-15-6-5-14(7-16(15)22)17(28)11-29-19-10-24-9-18-25-26-20(27(18)19)13-3-1-12(8-23)2-4-13/h1-7,9-10,17,28H,11H2
gh178
@alintheopen alintheopen self-assigned this Apr 14, 2014
@alintheopen alintheopen changed the title (E)-N-(2-chloro-5-fluorobenzyl)-6-(2-(4-cyanobenzylidene)hydrazinyl)pyrazine-2-carboxamide N-(2-chloro-5-fluorobenzyl)-3-(4-(trifluoromethoxy)phenyl)-[1,2,4]triazolo[4,3-a]pyrazine-5-carboxamide May 2, 2014
@alintheopen alintheopen reopened this May 2, 2014
@alintheopen alintheopen changed the title N-(2-chloro-5-fluorobenzyl)-3-(4-(trifluoromethoxy)phenyl)-[1,2,4]triazolo[4,3-a]pyrazine-5-carboxamide Racemic synthesis of 4-(5-(2-(3,4-difluorophenyl)-2-hydroxyethoxy)-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)benzonitrile May 2, 2014
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mattodd commented Jun 29, 2014

Still active @alintheopen or superseded?

@alintheopen
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Still active....WTS

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mattodd commented Dec 10, 2014

Still a target? - this is related to #235 - we probably don't need both.

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