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Incorrect ScaleFactor Calculation in Toblerone Software？ #2

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Xie-Bo-2018 opened this issue Jun 20, 2023 · 1 comment
Open

Incorrect ScaleFactor Calculation in Toblerone Software？ #2

Xie-Bo-2018 opened this issue Jun 20, 2023 · 1 comment

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@Xie-Bo-2018
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Xie-Bo-2018 commented Jun 20, 2023 •
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There seems to be a potential issue with the calculation of the ScaleFactor. In the paper, it is stated as "ScaleFactor = GeneLength / ReadLength", but in the software's results, it appears to be "ScaleFactor = ReadLength / GeneLength", and the calculated value is incorrect. The expected value should be 150/6255 = 0.02398, instead of 0.04796.
@Xie-Bo-2018
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is it because of double weighting of paired-end reads?

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