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Data and code for biofilm pharmacodynamics model

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RothLabRU/Biofilm-PD

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Biofilm-PD

Data and code to reproduce model by Roychowdhury and Roth describing biofilm response to antibiotics in a flow cell environment

Files:

MATLAB File Explanation
Read_New1.m, Muskerror_New1.m Error and optimization functions
TOBContinuousTreatment.m, Musken_5Comp.m Continuous treatment for 5, 20, and 50 micrograms/mL of TOB
TOB4HRCombined.m, Musken_wKs_after4.m 4 hour treatment for for 5, 20, and 50 micrograms/mL of TOB
CSTContFINAL.m, CST_OneComp.m Continuous treatment for 2.5, 10, and 25 micrograms/mL of CST
CST4hr_FINAL.m 4 hour treatment for 2.5, 10, and 25 micrograms/mL of CST
CombinedTOB5CST10.m, CombineCST_TOB_New.m Combination treatement of TOB and CST (for multple concentrations)
WithoutPara.m, Musken_woA.m, Musken_woB.m, Musken_woKt.m, Musken_woN.m, Musken_woU.m How the model would be affected without each parameter
ParaSensitivity.m Parametric sensitivity of the used parameters

The Excel files contain the data points digitized at different drug concentrations from Musken that were used to validate the model.

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Data and code for biofilm pharmacodynamics model

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