Reduced draft ME model of E. coli.
- Citation for final model: TBA
Reduced ME model for rapid prototyping
A reduced ME model. Mathematical formulation: max mu, s.t. S*v = b, mu*A*v + B*v = 0, lb <= v <= ub,
where v is the vector of fluxes in mmol/gDW/h (both metabolic and expression), and mu is the growth rate (1/h).
Standard double-precision solvers do not work well due to the multiscale nature of ME models. Therefore, a quad-precision-based solver suite (solveME) has been developed in a related effort: Yang, Ma, et al. (2016) BMC Bioinf 17:391.