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NIF-Subcellular.ttl
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NIF-Subcellular.ttl
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@prefix : <file:///ERROR/EMPTY/PREFIX/BANNED/> .
@prefix BFO: <http://purl.obolibrary.org/obo/BFO_> .
@prefix BIRNLEX: <http://uri.neuinfo.org/nif/nifstd/birnlex_> .
@prefix dc: <http://purl.org/dc/elements/1.1/> .
@prefix hasPart: <http://purl.obolibrary.org/obo/BFO_0000051> .
@prefix NIFEXT: <http://uri.neuinfo.org/nif/nifstd/nifext_> .
@prefix NIFRID: <http://uri.neuinfo.org/nif/nifstd/readable/> .
@prefix NIFSTD: <http://uri.neuinfo.org/nif/nifstd/> .
@prefix NLX: <http://uri.neuinfo.org/nif/nifstd/nlx_> .
@prefix NLXSUB: <http://uri.neuinfo.org/nif/nifstd/nlx_subcell_> .
@prefix oboInOwl: <http://www.geneontology.org/formats/oboInOwl#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix SAO: <http://uri.neuinfo.org/nif/nifstd/sao> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix xml: <http://www.w3.org/XML/1998/namespace> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
<http://ontology.neuinfo.org/NIF/ttl/NIF-Subcellular.ttl> a owl:Ontology ;
owl:imports <http://ontology.neuinfo.org/NIF/ttl/nif_backend.ttl> ;
dc:title "NIF-Subcellular: contains cell parts and subcellular structures from SAO-CORE and Gene Ontology Cellular Component (GO-CC)"^^xsd:string ;
rdfs:comment "next ID: nlx_subcell_20090212"^^xsd:string ;
skos:changeNote """v1.1 (February, 2009) - * Duplicate classes from SAO (sao_ and nifext_ prefixed IDs) has been eliminated as identified in the NeuroLex wiki. While retiring the duplicate classes, kept the ones with most detailed annotations or merged the annotation (synonyms, definitions etc) into the ones that had more/better information regardless of their IDs with sao or nifext prefixes. * Not all sao prefixed IDs are out of date or replaced by nifext.
v.1.0 (January, 2009) - Updated with simplified import hierarchy of upper level ontologies as part of the transition from NIFSTD 0.5 to 1.0.
v1.2 (July, 2009) - New terms have been added since the January release (ID used: nlx_subcell_20090101 - 20090703)
v1.3 (May, 2012) - New terms have been added from NeuroLex.
v1.3.1 (July, 2013) - Older PURL links are replaced with the new ones."""^^xsd:string ;
owl:versionInfo "1.3.1 (July 15, 2013)"^^xsd:string ;
oboInOwl:hasSubset <http://purl.obolibrary.org/obo/goslim_candida>,
<http://purl.obolibrary.org/obo/goslim_generic>,
<http://purl.obolibrary.org/obo/goslim_goa>,
<http://purl.obolibrary.org/obo/goslim_pir>,
<http://purl.obolibrary.org/obo/goslim_plant>,
<http://purl.obolibrary.org/obo/goslim_yeast>,
<http://purl.obolibrary.org/obo/gosubset_prok> .
### Object Properties
hasPart: a owl:ObjectProperty .
NIFRID:has_proper_part a owl:ObjectProperty .
NIFRID:proper_part_of a owl:ObjectProperty .
### Classes
BIRNLEX:10 a owl:Class ;
owl:deprecated true ;
rdfs:label "Constitutional part of cell"^^xsd:string ;
rdfs:subClassOf owl:DeprecatedClass ;
NIFRID:createdDate "2006-09-07"^^xsd:string ;
dc:contributor "Bill Bug"^^xsd:string ;
NIFRID:hasExternalSource "UMLS"^^xsd:string ;
skos:example "cytoskeletal system"^^xsd:string,
"post-synaptic density"^^xsd:string .
BIRNLEX:13 a owl:Class ;
rdfs:label "Sample population"^^xsd:string ;
skos:prefLabel "Sample population"^^xsd:string ;
rdfs:subClassOf SAO:2254405550 ;
NIFRID:createdDate "2006-09-07"^^xsd:string ;
NIFRID:modifiedDate "2006-10-09"^^xsd:string ;
NIFRID:hasBirnlexCurator NIFRID:Bill_Bug ;
NIFRID:tempDefinition "A defined subset of a population whose spatio-temporal interactions or aggregate behavior is representative of the whole population."^^xsd:string .
BIRNLEX:788 a owl:Class ;
owl:deprecated true ;
rdfs:label "Microtubule"^^xsd:string ;
skos:prefLabel "Microtubule"^^xsd:string ;
rdfs:subClassOf owl:DeprecatedClass ;
owl:disjointWith BIRNLEX:879,
BIRNLEX:888 ;
NIFRID:createdDate "2006-07-15"^^xsd:string ;
NIFRID:modifiedDate "2006-09-28"^^xsd:string ;
NIFRID:hasBirnlexCurator NIFRID:Maryann_Martone ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:hasExternalSource NIFRID:UMLS ;
NIFRID:isReplacedByClass SAO:1846835077 ;
NIFRID:UmlsCui "C0026046"^^xsd:string .
BIRNLEX:846 a owl:Class ;
owl:deprecated true ;
rdfs:label "Neurofilament"^^xsd:string ;
skos:prefLabel "Neurofilament"^^xsd:string ;
rdfs:subClassOf owl:DeprecatedClass ;
NIFRID:createdDate "2006-07-15"^^xsd:string ;
NIFRID:modifiedDate "2006-09-28"^^xsd:string ;
NIFRID:hasBirnlexCurator NIFRID:BIRN_OTF ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:isReplacedByClass SAO:1316272517 .
BIRNLEX:878 a owl:Class ;
owl:deprecated true ;
rdfs:label "Cytoskeletal system"^^xsd:string ;
NIFRID:synonym "cytoskeleton"^^xsd:string ;
rdfs:subClassOf owl:DeprecatedClass ;
NIFRID:createdDate "2006-07-15"^^xsd:string ;
NIFRID:modifiedDate "February 18, 2010"^^xsd:string ;
dc:contributor "Maryann Martone"^^xsd:string ;
NIFRID:isReplacedByClass SAO:1635329413 .
BIRNLEX:879 a owl:Class ;
owl:deprecated true ;
rdfs:label "Intermediate filament"^^xsd:string ;
skos:prefLabel "Intermediate filament"^^xsd:string ;
rdfs:subClassOf owl:DeprecatedClass ;
owl:disjointWith BIRNLEX:888 ;
NIFRID:createdDate "2006-07-15"^^xsd:string ;
NIFRID:modifiedDate "2006-09-28"^^xsd:string ;
NIFRID:birnlexDefinition "Cytoskeletal element consisting of elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: keratin filaments of mammalian epithelial cells; desmin filaments found in cells of muscles of all types; vimentin filaments found in mesenchymal cells; neurofilaments of neurons; and glial filaments found in all types of glial cells (Gene Ontology)."^^xsd:string ;
NIFRID:hasBirnlexCurator NIFRID:Maryann_Martone ;
NIFRID:hasCurationStatus NIFRID:pending_final_vetting ;
NIFRID:hasExternalSource NIFRID:UMLS ;
NIFRID:isReplacedByClass SAO:952483289 ;
NIFRID:UmlsCui "C0021770"^^xsd:string .
BIRNLEX:886 a owl:Class ;
owl:deprecated true ;
rdfs:label "Post synaptic density"^^xsd:string ;
skos:prefLabel "Post synaptic density"^^xsd:string ;
rdfs:subClassOf owl:DeprecatedClass ;
NIFRID:createdDate "2006-07-15"^^xsd:string ;
NIFRID:modifiedDate "2006-09-28"^^xsd:string ;
NIFRID:bonfireID "BF_C000103"^^xsd:string ;
NIFRID:hasBirnlexCurator NIFRID:Maryann_Martone ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:isReplacedByClass SAO:1196688972 .
BIRNLEX:888 a owl:Class ;
owl:deprecated true ;
rdfs:label "Microfilament"^^xsd:string ;
skos:prefLabel "Microfilament"^^xsd:string ;
rdfs:subClassOf owl:DeprecatedClass ;
NIFRID:createdDate "2006-07-15"^^xsd:string ;
NIFRID:modifiedDate "2006-09-28"^^xsd:string ;
NIFRID:hasBirnlexCurator NIFRID:BIRN_OTF ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:isReplacedByClass SAO:2006047981 .
BIRNLEX:1142 a owl:Class ;
owl:deprecated true ;
rdfs:label "Neuropil"^^xsd:string ;
skos:prefLabel "Neuropil"^^xsd:string ;
rdfs:subClassOf owl:DeprecatedClass ;
rdfs:comment "This class has been retired."^^xsd:string ;
NIFRID:createdDate "2006-07-15"^^xsd:string ;
NIFRID:modifiedDate "May 15, 2009"^^xsd:string ;
NIFRID:externallySourcedDefinition "Supracellular structure consisting of a dense intricate feltwork of interwoven fine glial processes, fibrils, synaptic terminals, axons, and dendrites interspersed among the nerve cells in the gray matter of the central nervous system."^^xsd:string ;
NIFRID:hasBirnlexCurator NIFRID:Maryann_Martone ;
NIFRID:hasCurationStatus NIFRID:pending_final_vetting ;
NIFRID:hasDefinitionSource NIFRID:MeSH_defSource ;
NIFRID:hasExternalSource NIFRID:UMLS ;
NIFRID:hasFormerParentClass BIRNLEX:3 ;
NIFRID:isReplacedByClass SAO:205380252 ;
NIFRID:UmlsCui "C0228081"^^xsd:string .
BIRNLEX:1152_2 a owl:Class ;
rdfs:label "Node of Ranvier"^^xsd:string ;
skos:prefLabel "Node of Ranvier"^^xsd:string ;
skos:definition "Site located at the gaps in the myelin sheaths of myelinated axons. Axon diameter is generally decreased in the nodal region, compared to the internode. Ranvier's nodes allow saltatory conduction, that is, jumping of impulses from node to node, which is faster and more energetically favorable than continuous conduction (MSH)."^^xsd:string ;
rdfs:subClassOf SAO:596411490 ;
NIFRID:createdDate "2006-07-15"^^xsd:string ;
NIFRID:modifiedDate "2006-09-28"^^xsd:string ;
NIFRID:birnlexDefinition "Specialized supracellular structures found in myelinated axons at the gaps between the myelin sheaths. The Node of Ranvier consists of the axonal membrane at the gap, the surrounding myelin processes and additional components such as astrocytic processes or basal lamina, depending upon whether the Node occurs in axons in the peripheral or central nervous system."^^xsd:string ;
NIFRID:hasBirnlexCurator NIFRID:Maryann_Martone ;
NIFRID:hasCurationStatus NIFRID:pending_final_vetting ;
NIFRID:hasExternalSource NIFRID:UMLS ;
NIFRID:UmlsCui "C0034667"^^xsd:string .
BIRNLEX:2534 a owl:Class ;
rdfs:label "Intrinsic neuron role"^^xsd:string ;
skos:prefLabel "Intrinsic neuron role"^^xsd:string ;
NIFRID:synonym "intrinsic neuron"^^xsd:string,
"local circuit neuron"^^xsd:string,
"local circuit neuron role"^^xsd:string ;
rdfs:subClassOf BIRNLEX:2537 ;
owl:disjointWith NLXSUB:1008001 ;
rdfs:comment "We are leaving off \"interneuron\" for now, as it has different connotations in vertebrates and invertebrates"^^xsd:string ;
NIFRID:createdDate "2007-08-26"^^xsd:string ;
NIFRID:modifiedDate "March 31, 2009"^^xsd:string ;
NIFRID:hasBirnlexCurator NIFRID:Bill_Bug ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:tempDefinition "An interneuron participating in aneuronal circuit where all the neurons are bounded within a defined and limited region of the nervous system.(BB)."^^xsd:string .
BIRNLEX:2536 a owl:Class ;
rdfs:label "Functional role of cell"^^xsd:string ;
skos:prefLabel "Functional role of cell"^^xsd:string ;
rdfs:subClassOf NLXSUB:090803 ;
NIFRID:createdDate "2007-08-25"^^xsd:string ;
NIFRID:modifiedDate "August 20, 2009"^^xsd:string ;
NIFRID:hasBirnlexCurator NIFRID:Bill_Bug ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:hasFormerParentClass BFO:0000023 .
BIRNLEX:2537 a owl:Class ;
rdfs:label "Functional role of nerve cell"^^xsd:string ;
skos:prefLabel "Functional role of nerve cell"^^xsd:string ;
rdfs:subClassOf BIRNLEX:2536 ;
NIFRID:createdDate "2007-08-25"^^xsd:string ;
NIFRID:modifiedDate "2007-08-25"^^xsd:string ;
NIFRID:hasBirnlexCurator NIFRID:Bill_Bug ;
NIFRID:hasCurationStatus NIFRID:uncurated .
NIFEXT:142 a owl:Class ;
rdfs:subClassOf owl:DeprecatedClass .
NIFSTD:FMA_83604 a owl:Class ;
rdfs:label "Pacinian corpuscle"^^xsd:string ;
skos:definition "Encapsulated nerve ending located in skin composed of nerve ending of a dorsal root ganglion neuron wrapped in 20-60 concentric lamellae composed of fibrous tissue and fibroblasts. They function as mechanoreceptors for pressure (adapted from Wikipedia)"^^xsd:string ;
rdfs:subClassOf NLXSUB:20090505 ;
NIFRID:createdDate "February 23, 2010"^^xsd:string ;
NIFRID:definingCitation "Foundational Model of Anatomy"^^xsd:string .
NIFSTD:FMA_83605 a owl:Class ;
rdfs:label "Meissners corpuscle"^^xsd:string ;
NIFRID:synonym "Meisner's corpuscle"^^xsd:string,
"Meisners corpuscle"^^xsd:string,
"Meissner's corpuscle"^^xsd:string,
"tactile corpuscle"^^xsd:string ;
skos:definition "Meissner's corpuscles are encapsulated nerve endings of dorsal root ganglion cells. They are located in skin, which consist of flattened supportive cells arranged as horizontal lamellae surrounded by a connective tissue capsule, that function as mechanoreceptors for light touch. The corpuscle is between 30-140 μm in length and 40-60 μm in diameter."^^xsd:string ;
rdfs:subClassOf NLXSUB:20090505 .
NIFSTD:FMA_83606 a owl:Class ;
rdfs:label "Merkels disc"^^xsd:string ;
NIFRID:synonym "Merkel cell-neurite complex"^^xsd:string,
"Merkel disk receptor"^^xsd:string,
"Merkel's disc"^^xsd:string,
"Merkel's disk"^^xsd:string ;
skos:definition "Encapsulated nerve ending formed by the neurite of a dorsal root ganglion cell in close apposition to a Merkel cell found in the basal layer of glabrous and hairy skin, in hair follicles, and in oral and anal mucosa. The Merkel disc functions as a sensory receptor for pressure and texture information (adapted from Wikipedia)"^^xsd:string ;
rdfs:subClassOf NLXSUB:20090505 ;
NIFRID:createdDate "February 23, 2010"^^xsd:string ;
NIFRID:definingCitation "Foundational Model of Anatomy"^^xsd:string .
NLX:330 a owl:Class ;
rdfs:label "Parallel fiber"^^xsd:string ;
skos:definition "Regional part of a cerebellar granule cell axon referring to the bifurcation of the granule cell axon in the molecular layer into two diametrically opposed branches that are oriented parallel to the long axis of the folium. (adapted from Shepherd, G. M. The synaptic organization of the brain, 5th ed. New York: Oxford University Press, 2004."^^xsd:string ;
rdfs:subClassOf NLXSUB:100307 ;
NIFRID:createdDate "March 17, 2010"^^xsd:string .
NLX:467 a owl:Class ;
rdfs:label "Thorny excrescence"^^xsd:string ;
skos:definition "Large complex spine. Each excrescence is formed by a cluster of spine heads (Amaral, 1978)"^^xsd:string ;
rdfs:subClassOf SAO:1799103720 ;
NIFRID:createdDate "May 11, 2010"^^xsd:string ;
NIFRID:definingCitation "The Hippocampus book by Andersen et al."^^xsd:string .
NLX:151681 a owl:Class ;
rdfs:label "Complex laminated body" ;
dc:description "Cytoplasmic organelles described in some lateral geniculate neurons composed of sheets of tubules (25 nm in diameter) separated by dense material (about 75 nm wide), which together with the tubules whorl give a structure resembling a 'finger-print '. In 2 um thick Epon-Araldite sections stained with methylene-blue and Azure II, CLBs are dark blue, round or oval bodies of the same order of size as the nucleolus."@en ;
rdfs:subClassOf SAO:506721981 ;
owl:versionInfo "201976"@en ;
NIFRID:createdDate "November 8, 2012"@en ;
dc:contributor "Maryann Martone"@en ;
NIFRID:definingCitation "Winfield DA (1982) A quantitative study of the complex laminated body in the lateral geniculate nucleus of the cat. Brain Res 235: 17-30. PubMed:7188322"@en .
NLXSUB:090801 a owl:Class ;
rdfs:label "Glial Inclusion"^^xsd:string ;
skos:prefLabel "Glial Inclusion"^^xsd:string ;
NIFRID:synonym "Argyrophilic Glial Inclusion"^^xsd:string ;
rdfs:subClassOf SAO:120573470 ;
NIFRID:createdDate "August 11, 2009"^^xsd:string ;
dc:contributor "Jane Bugea"^^xsd:string .
NLXSUB:090802 a owl:Class ;
rdfs:label "Neuronal Cytoplasmic Inclusion"^^xsd:string ;
skos:prefLabel "Neuronal Cytoplasmic Inclusion"^^xsd:string ;
NIFRID:abbrev "NCI"^^xsd:string ;
rdfs:subClassOf SAO:120573470 ;
NIFRID:createdDate "August 11, 2009"^^xsd:string ;
dc:contributor "Jane Bugea"^^xsd:string .
NLXSUB:090803 a owl:Class ;
rdfs:label "Cell role"^^xsd:string ;
rdfs:subClassOf BFO:0000023 ;
NIFRID:createdDate "August 20, 2009"^^xsd:string .
NLXSUB:090901 a owl:Class ;
rdfs:label "Cajal body"^^xsd:string ;
NIFRID:synonym "Coiled body"^^xsd:string ;
rdfs:subClassOf SAO:120573470 ;
NIFRID:createdDate "August 31, 2009"^^xsd:string ;
NIFRID:modifiedDate "February 17, 2010"^^xsd:string ;
dc:contributor "Jane Bugea"^^xsd:string ;
NIFRID:definingCitationURI <http://genetics.cwru.edu/matera3.html> ;
NIFRID:gene_Ontology_ID "GO_0015030"^^xsd:string .
NLXSUB:091021 a owl:Class ;
rdfs:label "Mossy fiber rosette"^^xsd:string ;
skos:definition "A synapse of the mossy fiber onto the dendrite of a granule cell; each mossy fiber can have up to 50 rosettes. (source: http://www.neuroanatomy.wisc.edu/cere/text/P4/mossy.htm) (http://en.wikipedia.org/wiki/Mossy_fiber_(cerebellum))"^^xsd:string ;
rdfs:subClassOf SAO:914572699 ;
NIFRID:createdDate "October 5, 2009"^^xsd:string ;
dc:contributor "Sarah M. Maynard"^^xsd:string .
NLXSUB:100203 a owl:Class ;
rdfs:label "Grumose foamy spheroid body"^^xsd:string ;
skos:definition "Grumose foamy spheroid body is a spheroidal supracellular structure with a foamy appearance in haematoxylin and eosin stains that vary from 10 to 50 microns in diameter and contain amorphous debris-like material found in the brains in certain neurodegenerative conditions."^^xsd:string ;
rdfs:subClassOf SAO:508165343 ;
NIFRID:createdDate "February 12, 2010"^^xsd:string ;
NIFRID:PMID "PMID: 7477732"^^xsd:string .
NLXSUB:100205 a owl:Class ;
rdfs:label "Blood brain barrier"^^xsd:string ;
NIFRID:synonym "Blood-brain barrier"^^xsd:string ;
NIFRID:abbrev "BBB"^^xsd:string ;
skos:definition "A supracellular structure formed by tight junctions between capillary endothelial cells in the brain that prevents substances from entering the brain from the vasculature, except by passage of substances through the endothelial cell."^^xsd:string ;
rdfs:subClassOf SAO:508165343 ;
rdfs:comment "The BBB has also been defined physiologically"^^xsd:string .
NLXSUB:100206 a owl:Class ;
rdfs:label "F bouton"^^xsd:string ;
skos:definition "Synaptic bouton found in the ventral horn of the spinal cord that range in diameter from 0.5 to 7 um and contain flattened or pleomorphic synaptic vesicles in electron microscopic preparations."^^xsd:string ;
rdfs:subClassOf SAO:187426937 ;
NIFRID:createdDate "February 23, 2010"^^xsd:string .
NLXSUB:100207 a owl:Class ;
rdfs:label "S bouton"^^xsd:string ;
skos:definition "Synaptic bouton found in the ventral horn of the spinal cord. S boutons range in size from 0.5 to 8 um in diameter and contain spherical synaptic vesicles, as determined by electron microscopy"^^xsd:string ;
rdfs:subClassOf SAO:187426937 ;
NIFRID:createdDate "February 23, 2010"^^xsd:string .
NLXSUB:100208 a owl:Class ;
rdfs:label "C bouton"^^xsd:string ;
skos:definition "Synaptic bouton found in spinal cord on the soma and proximal dendrites of motor neurons"^^xsd:string ;
rdfs:subClassOf SAO:187426937 ;
NIFRID:createdDate "February 23, 2010"^^xsd:string .
NLXSUB:100209 a owl:Class ;
rdfs:label "Glia limitans"^^xsd:string ;
NIFRID:synonym "glial limiting membrane"^^xsd:string ;
skos:definition "The meshwork of astrocytic foot processes (glial end feet) covered by a basal lamina adjacent to the inner pial surface of the central nervous system."^^xsd:string ;
rdfs:subClassOf SAO:508165343 ;
NIFRID:createdDate "February 10, 2010"^^xsd:string .
NLXSUB:100210 a owl:Class ;
rdfs:label "Glial scar"^^xsd:string ;
skos:definition "Fibrous scar consisting predominately of reactive astrocytes, microglia and extracellular matrix molecules formed after injury to the central nervous system (adapted from Rolls et al., Nature Reviews Neuroscience 10: 235, 2009)"^^xsd:string ;
rdfs:subClassOf SAO:508165343 .
NLXSUB:100307 a owl:Class ;
rdfs:label "Regional Part Of Granule Cell Axon"^^xsd:string ;
rdfs:subClassOf SAO:280355188 ;
NIFRID:createdDate "March 17, 2010"^^xsd:string .
NLXSUB:100312 a owl:Class ;
rdfs:label "Hippocampal mossy fiber"^^xsd:string ;
NIFRID:synonym "Dentate gyrus mossy fiber"^^xsd:string ;
skos:definition "Axon of dentate gyrus granule cell projecting to hippocampal area CA3, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal."^^xsd:string ;
rdfs:subClassOf SAO:1770195789 ;
NIFRID:createdDate "March 18, 2010"^^xsd:string ;
NIFRID:modifiedDate "April 28, 2010"^^xsd:string .
NLXSUB:100315 a owl:Class ;
rdfs:label "Subcellular entity"^^xsd:string ;
skos:altLabel "subcellular_structure"^^xsd:string ;
skos:definition "Entity derived from a cell or cells. The anatomical scale of these objects roughly corresponds to that which would be visible in high resolution light microscopy or conventional electron microscopy, e.g., nanometers to microns. Example: mitochondrion, dendrite, extracellular matrix."^^xsd:string ;
rdfs:subClassOf BFO:0000040 ;
NIFRID:createdDate "March 15, 2010"^^xsd:string ;
dc:contributor "Maryann Marotone"^^xsd:string .
NLXSUB:1005001 a owl:Class ;
rdfs:label "CA3 pyramidal cell dendrite"^^xsd:string ;
skos:definition "Dendrite of a hippocampal CA3 pyramidal cell"^^xsd:string ;
rdfs:subClassOf SAO:1211023249 ;
NIFRID:createdDate "May 11, 2010"^^xsd:string .
NLXSUB:1005002 a owl:Class ;
rdfs:label "Hippocampal mossy fiber expansion"^^xsd:string ;
NIFRID:synonym "dentate gyrus granule cell axonal bouton"^^xsd:string,
"dentate gyrus mossy fiber expansion"^^xsd:string,
"mossy fiber expansion"^^xsd:string ;
skos:definition "Synaptic expansion of hippocampal mossy fiber axon that makes contact with the thorny excrescences of hippocampal CA3 pyramidal cell dendrites"^^xsd:string ;
rdfs:subClassOf SAO:187426937 ;
NIFRID:createdDate "May 11, 2010"^^xsd:string .
NLXSUB:1005003 a owl:Class ;
rdfs:label "Gemmule"^^xsd:string ;
skos:definition "spine-like process found on some neurons, e.g., periglomerular cells of olfactory cortex"^^xsd:string ;
rdfs:subClassOf SAO:250931889 ;
NIFRID:createdDate "May 11, 2010"^^xsd:string .
NLXSUB:1008001 a owl:Class ;
rdfs:label "Principal neuron role"^^xsd:string ;
skos:prefLabel "Principal neuron role"^^xsd:string ;
NIFRID:synonym "Principal neuron"^^xsd:string,
"Projection neuron"^^xsd:string,
"Projection neuron role"^^xsd:string ;
rdfs:subClassOf BIRNLEX:2537 ;
NIFRID:createdDate "2007-08-26"^^xsd:string ;
NIFRID:modifiedDate "March 31, 2009"^^xsd:string ;
NIFRID:hasBirnlexCurator NIFRID:Bill_Bug ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:tempDefinition "A principal projection neuron in a neuronal circuit whose axon extends beyond the region where its soma is located to synapse on the dendrites of cells in other regions of the nervous system (BB)."^^xsd:string ;
skos:example "CA3 Pyramidal neurons are principal neurons projecting out of the CA3 cytoarchitectural part of the hippocampus of vertebrates."^^xsd:string,
"Cerebellar Purkinje neurons are principal neurons projecting out from the cerebellar cortex of vertebrates."^^xsd:string .
NLXSUB:20090101 a owl:Class ;
rdfs:label "Bunina Body"^^xsd:string ;
skos:prefLabel "Bunina Body"^^xsd:string ;
skos:definition "Bunina bodies are small eosinphilic granular inclusions that are 1-3 microns in diameter in the anterior horn cells, appearing either singly or in a group. Sometimes they are arranded in small beaded chains. They stain bright red with hematoxylin and eosin (H&E) staining, deep blue with phospotungstic acid hematoxylin and blue with Luxol fast blue. They express cystatin C and consist of electron-dense amorphous material that contains tubules or vesicular structures. The amorphous material frequently includes a cytoplasmis island containing neurofilaments and other micro-organelles."^^xsd:string ;
rdfs:subClassOf SAO:120573470 ;
NIFRID:createdDate "January 9, 2009"^^xsd:string ;
dc:contributor "Sarah M. Maynard"^^xsd:string ;
NIFRID:definingCitationID "PMID: 18026741"^^xsd:string .
NLXSUB:20090102 a owl:Class ;
rdfs:label "Pick Body"^^xsd:string ;
skos:prefLabel "Pick Body"^^xsd:string ;
skos:definition "Pick Bodies are composed of numerous tau fibrils arranged in a disorderly array. Tau protein is a major component. Pick bodies also stain for ubiquitin, alpha-synuclein, and apolipoprotein E."^^xsd:string ;
rdfs:subClassOf SAO:120573470 ;
NIFRID:createdDate "January 9, 2009"^^xsd:string ;
dc:contributor "Sarah M. Maynard"^^xsd:string .
NLXSUB:20090103 a owl:Class ;
rdfs:label "Skein-like Inclusion"^^xsd:string ;
skos:prefLabel "Skein-like Inclusion"^^xsd:string ;
skos:definition "Skein-like inclusions are intracytoplasmic filamentous structures that are frequently encountered in preparations immunostained for ubiquitin. In H&E preparations (staining with hematoxylin and eosin) they are hardly visible or sometimes detected as faintly eosinophilic structures."^^xsd:string ;
rdfs:subClassOf SAO:120573470 ;
NIFRID:createdDate "January 9, 2009"^^xsd:string ;
dc:contributor "Sarah M. Maynard"^^xsd:string ;
NIFRID:definingCitationID "PMID: 18026741"^^xsd:string .
NLXSUB:20090104 a owl:Class ;
rdfs:label "Hyaline Inclusion"^^xsd:string ;
skos:prefLabel "Hyaline Inclusion"^^xsd:string ;
skos:definition "Pale eosinophilic inclusions with halos in H&E (hematoxylin and eosin) preparations."^^xsd:string ;
rdfs:subClassOf SAO:120573470 ;
NIFRID:createdDate "January 9, 2009"^^xsd:string ;
dc:contributor "Sarah M. Maynard"^^xsd:string .
NLXSUB:20090105 a owl:Class ;
rdfs:label "Lewy Body-like Hyaline Inclusion"^^xsd:string ;
skos:prefLabel "Lewy Body-like Hyaline Inclusion"^^xsd:string ;
skos:definition "In H&E preparations, neuronal LBHIs show an eosinphilic core with a paler peripheral halo, and their name is derived from their H&E staining features, which resemble those of Lewy bodies in patients with Parkinson's disease. Neuronal Lewy Body-like Hyaline Inclusions consist of filaments and granular materials, exhibit dense cores with rough preipheral halos and lack a limiting membrane. The filaments of these inclusions are composed of approximately 15-25 nm granule-coated fibrils in association with normal 10-nm neurofilaments."^^xsd:string ;
rdfs:subClassOf SAO:120573470 ;
NIFRID:createdDate "January 9, 2009"^^xsd:string ;
dc:contributor "Sarah M. Maynard"^^xsd:string ;
NIFRID:definingCitation "Kato S. 2008 Amyotrophic lateral sclerosis models and human neuropathology: similarities and differences. Acta Neuropathol 115:97-114. page 101"^^xsd:string .
NLXSUB:20090106 a owl:Class ;
rdfs:label "Transferrin"^^xsd:string ;
skos:prefLabel "Transferrin"^^xsd:string ;
skos:definition "Transferrin is a blood plasma protein for iron ion delivery which in humans is encoded by the TF gene."^^xsd:string ;
rdfs:subClassOf SAO:26622963 ;
NIFRID:createdDate "January 9, 2009"^^xsd:string ;
dc:contributor "Sarah M. Maynard"^^xsd:string .
NLXSUB:20090201 a owl:Class ;
rdfs:label "Star-shaped Neurofibrillary Tangle"^^xsd:string ;
skos:prefLabel "Star-shaped Neurofibrillary Tangle"^^xsd:string ;
rdfs:subClassOf SAO:2409833926 ;
NIFRID:createdDate "February 12, 2009"^^xsd:string .
NLXSUB:20090202 a owl:Class ;
rdfs:label "Flame-shaped Neurofibrillary Tangle"^^xsd:string ;
skos:prefLabel "Flame-shaped Neurofibrillary Tangle"^^xsd:string ;
rdfs:subClassOf SAO:2409833926 ;
NIFRID:createdDate "February 12, 2009"^^xsd:string .
NLXSUB:20090203 a owl:Class ;
rdfs:label "Climbing fiber"^^xsd:string ;
skos:prefLabel "Climbing fiber"^^xsd:string ;
skos:definition "Axon of inferior olive neuron that projects to the cerebellar cortex, largely via the inferior cerebellar peduncle. They range in diameter from 1-3 um and are myelinated util they enter the granule cell layer. They give off collaterals to the deep cerebellar nuclei. They synapse extensively with the dendrites of Purkinje cells in the molecular layer, where each fiber branches repeatedly to \"climb\" along the Purkinje cell dendritic tree. Each Purkinje cell is innervated by only a single climbing fiber."^^xsd:string ;
rdfs:subClassOf SAO:1770195789 ;
NIFRID:createdDate "February 12, 2009"^^xsd:string ;
NIFRID:definingCitation "Shepherd, G. M. The Synaptic organization of the brain, 5th ed., New York: Oxford University Press, 2004."^^xsd:string .
NLXSUB:20090204 a owl:Class ;
rdfs:label "Astrocyte Sheath"^^xsd:string ;
skos:prefLabel "Astrocyte Sheath"^^xsd:string ;
rdfs:subClassOf SAO:1630537580 ;
NIFRID:createdDate "February 12, 2009"^^xsd:string .
NLXSUB:20090205 a owl:Class ;
rdfs:label "Cytochrome c"^^xsd:string ;
skos:prefLabel "Cytochrome c"^^xsd:string ;
skos:definition "A small heme protein found loosely associated with the inner membrane of the mitochondrion."^^xsd:string ;
rdfs:subClassOf SAO:26622963 ;
NIFRID:createdDate "February 23, 2009"^^xsd:string .
NLXSUB:20090206 a owl:Class ;
rdfs:label "Proteasome"^^xsd:string ;
skos:prefLabel "Proteasome"^^xsd:string ;
skos:definition "Proteasomes are large protein complexes inside all eukaryotes and archaea, as well as in some bacteria. In eukaryotes, they are located in the nucleus and the cytoplasm."^^xsd:string ;
rdfs:subClassOf SAO:26622963 ;
NIFRID:createdDate "February 23, 2009"^^xsd:string .
NLXSUB:20090207 a owl:Class ;
rdfs:label "Synaptophysin"^^xsd:string ;
skos:prefLabel "Synaptophysin"^^xsd:string ;
skos:definition "Synaptophysin (syp I) is a synaptic vesicle membrane protein"^^xsd:string ;
rdfs:subClassOf SAO:26622963 ;
NIFRID:createdDate "February 24, 2009"^^xsd:string .
NLXSUB:20090208 a owl:Class ;
rdfs:label "Endoneurial Space"^^xsd:string ;
skos:definition "The space occupied by the endoneurium."^^xsd:string ;
rdfs:subClassOf BFO:0000029 ;
NIFRID:createdDate "February 24, 2009"^^xsd:string .
NLXSUB:20090209 a owl:Class ;
rdfs:label "Cerebellar mossy fiber"^^xsd:string ;
skos:prefLabel "Cerebellar mossy fiber"^^xsd:string ;
skos:definition "Axon arising from cerebellar projecting cells in the cochlea, vestibular nuclei, spinal cord, reticular formation, cerebellar nuclei and basilar pontine nuclei. Mossy fibers enter through all three cerebellar peduncles and send collaterals to the deep cerebellar nuclei, then branch in the white matter and terminate in the granule cell layer. Through this branching, a given mossy fiber can innervate several folia. Mossy fibers synapse on granule cells. The synaptic contacts are made at enlargements along the length of the mossy fiber called mossy fiber rosettes. The enlargements of the rosettes give the axons as \"mossy\" appearance in Golgi stained preparations. (adapted from Shepherd, G. M. The synaptic organization of the brain, 5th ed. New York: Oxford University Press, 2004)."^^xsd:string ;
rdfs:subClassOf SAO:1770195789 ;
NIFRID:createdDate "February 27, 2009"^^xsd:string ;
NIFRID:definingCitation "Shepherd, G. M. The synaptic organization of the brain, 5th ed. New York: Oxford University Press, 2004"^^xsd:string .
NLXSUB:20090210 a owl:Class ;
rdfs:label "C-fiber"^^xsd:string ;
skos:prefLabel "C-fiber"^^xsd:string ;
skos:definition "The axon of dorsal root ganglion cells that are responsive to pain and temperature. C-fibers are small in diameter (0.2-1.5 um) and unmyelinated."^^xsd:string ;
rdfs:subClassOf SAO:1770195789 ;
NIFRID:createdDate "February 27, 2009"^^xsd:string .
NLXSUB:20090211 a owl:Class ;
rdfs:label "Calnexin"^^xsd:string ;
skos:prefLabel "Calnexin"^^xsd:string ;
skos:definition "Calnexin (CNX) is a 90kDa integral protein of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail."^^xsd:string ;
rdfs:subClassOf SAO:26622963 ;
NIFRID:createdDate "February 27, 2009"^^xsd:string .
NLXSUB:20090501 a owl:Class ;
rdfs:label "Triad"^^xsd:string ;
skos:definition "Synaptic arrangement observed in thalamic glomeruli consisting of a afferent terminal synapsing on both an interneuron axon terminal and the dendrite of a relay cell. The interneuron terminal also synapses on the dendrite of a relay cell, forming a triadic arrangement."^^xsd:string ;
rdfs:subClassOf SAO:205380252 ;
NIFRID:createdDate "May 15, 2009"^^xsd:string .
NLXSUB:20090502 a owl:Class ;
rdfs:label "Cerebellar glomerulus"^^xsd:string ;
rdfs:subClassOf SAO:587858733 ;
NIFRID:createdDate "May 16, 2009"^^xsd:string .
NLXSUB:20090503 a owl:Class ;
rdfs:label "Olfactory glomerulus"^^xsd:string ;
skos:definition "Glomerulus located in the olfactory bulb formed by the incoming axons of olfactory receptor cells synapsing onto the dendritic branches of one or more mitral cells. The olfactory glomerulus is roughly spherical and is partially or wholly encapsulated by glial processes."^^xsd:string ;
rdfs:subClassOf SAO:587858733 ;
NIFRID:createdDate "May 16, 2009"^^xsd:string ;
dc:contributor "Maryann Martone"^^xsd:string .
NLXSUB:20090504 a owl:Class ;
rdfs:label "Thalamic glomerulus"^^xsd:string ;
skos:definition "Synaptic structure found in thalamic relay nuclei consising of a complex of afferent terminals, relay cell dendrites, interneuron dendrites and other processes. These complexes are surrounded by astrocytic processes."^^xsd:string ;
rdfs:subClassOf SAO:587858733 ;
NIFRID:createdDate "May 16, 2009"^^xsd:string ;
NIFRID:definingCitation "Shepherd, G. M. The synaptic organization of the brain, 5th ed New York: Oxford University Press, 2005"^^xsd:string .
NLXSUB:20090505 a owl:Class ;
rdfs:label "Encapsulated nerve ending"^^xsd:string ;
skos:definition "Nerve ending found in skin surrounded by layers of connective tissue."^^xsd:string ;
rdfs:subClassOf SAO:508165343 ;
NIFRID:createdDate "May 17, 2009"^^xsd:string ;
dc:contributor "Maryann Martone"^^xsd:string .
NLXSUB:20090506 a owl:Class ;
rdfs:label "Axon bundle"^^xsd:string ;
NIFRID:synonym "Axon projection"^^xsd:string ;
skos:definition "Group of myelinated or unmyelinated axons that group together."^^xsd:string ;
rdfs:subClassOf NLXSUB:100315 ;
NIFRID:createdDate "May 17, 2009"^^xsd:string ;
dc:contributor "Maryann Martone"^^xsd:string ;
NIFRID:hasFormerParentClass SAO:3826089237 .
NLXSUB:20090507 a owl:Class ;
rdfs:label "Ipsilateral associatioinal commissural projection"^^xsd:string ;
NIFRID:synonym "Ipsilateral associational-commissural projection"^^xsd:string ;
skos:definition "Group of axons that arises from cells in the dentate gyrus polymorphic layer that terminate on the spines of granule cell dendrites on both the ipsilateral and contralateral sides."^^xsd:string ;
rdfs:subClassOf NLXSUB:20090506 ;
NIFRID:createdDate "May 17, 2009"^^xsd:string ;
dc:contributor "Maryann Martone"^^xsd:string ;
NIFRID:definingCitation "Shepherd, G. M. The synaptic organization of the brain, 5th ed New York: Oxford University Press, 2005"^^xsd:string .
NLXSUB:20090508 a owl:Class ;
rdfs:label "Perforant path"^^xsd:string ;
skos:definition "Axons arising from multipolar neurons in the entorhinal cortex projecting to the hippocampal formation. The fibers penetrate the hippocampal sulcus to terminate in the dentate gyrus and also project to area CA1 and the subiculum."^^xsd:string ;
rdfs:subClassOf NLXSUB:20090506 ;
NIFRID:createdDate "May 17, 2009"^^xsd:string ;
dc:contributor "Maryann Martone"^^xsd:string .
NLXSUB:20090509 a owl:Class ;
rdfs:label "Schaffer collaterals"^^xsd:string ;
skos:definition "Group of axons arising from hippocampal CA3 pyramidal neurons projecting to area CA1."^^xsd:string ;
rdfs:subClassOf NLXSUB:20090506 ;
NIFRID:createdDate "May 17, 2009"^^xsd:string ;
dc:contributor "Maryann Martone"^^xsd:string .
NLXSUB:20090510 a owl:Class ;
rdfs:label "Regional Part Of Pyramidal cell axon"^^xsd:string ;
rdfs:subClassOf SAO:280355188 ;
NIFRID:createdDate "May 19, 2009"^^xsd:string ;
dc:contributor "Maryann Martone"^^xsd:string .
NLXSUB:20090511 a owl:Class ;
rdfs:label "Schaffer collateral"^^xsd:string ;
skos:definition "Part of axon of the CA3 pyramidal neuron that projects to hippocampal area CA1 ."^^xsd:string ;
rdfs:subClassOf NLXSUB:20090510,
[ a owl:Restriction ;
owl:onProperty NIFRID:proper_part_of ;
owl:someValuesFrom NLXSUB:20090509 ] ;
NIFRID:createdDate "May 19, 2009"^^xsd:string ;
dc:contributor "Maryann Martone"^^xsd:string .
NLXSUB:20090512 a owl:Class ;
rdfs:label "Motor endplate"^^xsd:string ;
skos:definition "Terminal ending of the axon of a motor neuron that forms a synapse onto a muscle cell."^^xsd:string ;
rdfs:subClassOf SAO:187426937,
[ a owl:Restriction ;
owl:onProperty NIFRID:proper_part_of ;
owl:someValuesFrom SAO:1124888485 ] ;
NIFRID:createdDate "May 19, 2009"^^xsd:string ;
NIFRID:modifiedDate "February 23, 2010"^^xsd:string ;
dc:contributor "Maryann Martone"^^xsd:string .
NLXSUB:20090513 a owl:Class ;
rdfs:label "Extracellular matrix"^^xsd:string ;
skos:definition "A system of insoluble protein fibrils and soluble complexes composed of carbohydrate polymers linked to protein molecules, i.e. proteoglycans, in the extracellular space. Insoluble protein fibrils are mainly of two types: collagen and elastin; the soluble polymers consist of long carbohydrate chains, linked to proteins."^^xsd:string ;
rdfs:subClassOf SAO:9117790637 ;
rdfs:comment "Fmaid: 9672"^^xsd:string ;
NIFRID:createdDate "May 17, 2009"^^xsd:string ;
dc:contributor "Maryann Martone"^^xsd:string .
NLXSUB:20090601 a owl:Class ;
rdfs:label "Dentate gyrus mossy fiber"^^xsd:string ;
NIFRID:synonym "Granule cell axons"^^xsd:string ;
skos:definition "The granule cells give rise to distinctive unmyelinated axons referred to as mossy fibers by Ramón y Cajal."^^xsd:string ;
rdfs:subClassOf SAO:1770195789 ;
NIFRID:createdDate "June 18, 2009"^^xsd:string ;
dc:contributor "Maryann Martone"^^xsd:string ;
NIFRID:definingCitation "The dentate gyrus: fundamental neuroanatomical organization (dentate gyrus for dummies) by David G. Amaral, Helen E. Scharfman, and Pierre Lavenex"^^xsd:string ;
NIFRID:definingCitationID "PMID PMC2492885"^^xsd:string ;
NIFRID:PMID "PMC2492885"^^xsd:string .
NLXSUB:20090701 a owl:Class ;
rdfs:label "Early Endosome"^^xsd:string ;
skos:definition "Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered (GO: 0005769)."^^xsd:string ;
rdfs:subClassOf SAO:1720343330 ;
NIFRID:createdDate "July 14, 2009"^^xsd:string .
NLXSUB:20090702 a owl:Class ;
rdfs:label "Late Endosome"^^xsd:string ;
skos:definition "Late endosomes are vesicular structures that accumulate internalized components after their passage through early endosomes (GO: 0005700)."^^xsd:string ;
rdfs:subClassOf SAO:1720343330 ;
NIFRID:createdDate "July 14, 2009"^^xsd:string ;
NIFRID:definingCitation "Masa H. Sato, Ryosuke L Ohniwa, and Tomohiro Uemura, SNAREs in Plant Endocytosis and the Post-Golgi Traffic, Plant Cell Monogr, September 2005, DOI: 10.1007/7089 012"^^xsd:string .
NLXSUB:20090703 a owl:Class ;
rdfs:label "Glial Cytoplasmic Inclusion"^^xsd:string ;
skos:prefLabel "Glial Cytoplasmic Inclusion"^^xsd:string ;
rdfs:subClassOf SAO:120573470 ;
NIFRID:createdDate "July 14, 2009"^^xsd:string .
SAO:9456487 a owl:Class ;
rdfs:label "Trans Golgi Network"^^xsd:string ;
skos:prefLabel "Trans Golgi Network"^^xsd:string ;
skos:definition "A network of membrane compartments, located at the cytoplasmic side of the golgi apparatus, where proteins and lipids are sorted for transport to various locations in the cell or cell membrane (MSH)."^^xsd:string ;
rdfs:subClassOf SAO:1546288504 ;
NIFRID:gene_Ontology_ID "0005802"^^xsd:string ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao9456487"^^xsd:string ;
NIFRID:umls_ID "C0887838"^^xsd:string .
SAO:11978067 a owl:Class ;
rdfs:label "Basal Body"^^xsd:string ;
skos:prefLabel "Basal Body"^^xsd:string ;
skos:definition "A short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium or flagellum that is similar in structure to a centriole. The basal body serves as a nucleation site for axoneme growth (Gene Ontology)."^^xsd:string ;
rdfs:subClassOf SAO:1337158144 ;
owl:disjointWith SAO:120573470,
SAO:221389602,
SAO:628508602,
SAO:730872736,
SAO:787716553,
SAO:830981606,
SAO:1397492660,
SAO:1539965131,
SAO:1635329413,
SAO:1663586795,
SAO:1784069613,
SAO:1938587839,
SAO:1969557946 ;
NIFRID:gene_Ontology_ID "0005932"^^xsd:string ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao11978067"^^xsd:string ;
NIFRID:umls_ID "C0230744"^^xsd:string ;
skos:example <http://ccdb.ucsd.edu/SAO/images/basal_bodies_sw_512x512.jpg> .
SAO:18239917 a owl:Class ;
rdfs:label "Axonal Spine"^^xsd:string ;
skos:prefLabel "Axonal Spine"^^xsd:string ;
skos:definition "Refers to spine that originates from the axon, usually the initial segment (Peters, Palay and Webster, 1991)."^^xsd:string ;
rdfs:subClassOf SAO:1145756102 ;
owl:disjointWith SAO:2048514053 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao18239917"^^xsd:string .
SAO:18461326 a owl:Class ;
rdfs:label "Inner Bounding Mitochondrial Membrane"^^xsd:string ;
skos:prefLabel "Inner Bounding Mitochondrial Membrane"^^xsd:string ;
skos:definition "Part of mitochondrial inner membrane that runs parallel to the outer mitochondrial membrane"^^xsd:string ;
rdfs:subClassOf SAO:1686050947 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao18461326"^^xsd:string .
SAO:26622963 a owl:Class ;
rdfs:label "Protein"^^xsd:string ;
skos:prefLabel "Protein"^^xsd:string ;
rdfs:comment "This class classifies fine under 'Macromolecule' while loaded with NIF-Molecule.owl module."^^xsd:string ;
NIFRID:modifiedDate "March 18, 2009"^^xsd:string ;
NIFRID:hasCurationStatus "uncurated"^^xsd:string ;
NIFRID:hasFormerParentClass SAO:500241072 ;
NIFRID:sao_ID "sao26622963"^^xsd:string .
SAO:28175134 a owl:Class ;
rdfs:label "Terminal Specialization"^^xsd:string ;
skos:prefLabel "Terminal Specialization"^^xsd:string ;
rdfs:subClassOf SAO:420754792 ;
owl:disjointWith SAO:884265541 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao28175134"^^xsd:string .
SAO:82111036 a owl:Class ;
rdfs:label "Cell Protrusion"^^xsd:string ;
skos:prefLabel "Cell Protrusion"^^xsd:string ;
rdfs:subClassOf SAO:340271629 ;
owl:disjointWith SAO:864921383,
SAO:895885284 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao-82111036"^^xsd:string .
SAO:95019936 a owl:Class ;
rdfs:label "Centriole"^^xsd:string ;
skos:prefLabel "Centriole"^^xsd:string ;
skos:definition "A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle (Gene Ontology)."^^xsd:string ;
rdfs:subClassOf SAO:1456184038 ;
NIFRID:gene_Ontology_ID "0005814"^^xsd:string ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao95019936"^^xsd:string ;
NIFRID:umls_ID "C0007708"^^xsd:string ;
skos:example <http://ccdb.ucsd.edu/SAO/images/centriole_sw_512x512.jpg> .
SAO:101633890 a owl:Class ;
rdfs:label "Cytosol"^^xsd:string ;
skos:prefLabel "Cytosol"^^xsd:string ;
skos:definition "The part of the cytoplasm that does not contain membranous or particulate subcellular components (UMLS)."^^xsd:string ;
rdfs:subClassOf SAO:1337158144 ;
owl:disjointWith SAO:11978067,
SAO:120573470,
SAO:221389602,
SAO:628508602,
SAO:730872736,
SAO:787716553,
SAO:830981606,
SAO:1081228141,
SAO:1231384859,
SAO:1397492660,
SAO:1539965131,
SAO:1663586795,
SAO:1784069613,
SAO:1938587839 ;
NIFRID:gene_Ontology_ID "0005829"^^xsd:string ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao101633890"^^xsd:string ;
NIFRID:umls_ID "C0010854"^^xsd:string .
SAO:109906988 a owl:Class ;
rdfs:label "Pinceau Fiber"^^xsd:string ;
skos:prefLabel "Pinceau Fiber"^^xsd:string ;
skos:definition "Dense plexus formed by the descending collaterals of cerebellar basket cells tha wrap around the Purkinje cell axonal initial segment."^^xsd:string ;
rdfs:subClassOf SAO:1586851177 ;
owl:disjointWith SAO:413722576 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao109906988"^^xsd:string .
SAO:110773650 a owl:Class ;
rdfs:label "Dendritic Microtubule"^^xsd:string ;
skos:prefLabel "Dendritic Microtubule"^^xsd:string ;
rdfs:subClassOf SAO:1846835077 ;
owl:disjointWith SAO:248349196,
SAO:1872343973 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao110773650"^^xsd:string .
SAO:113580911 a owl:Class ;
rdfs:label "Regional Part Of Nucleolus"^^xsd:string ;
skos:prefLabel "Regional Part Of Nucleolus"^^xsd:string ;
rdfs:subClassOf SAO:1819020575 ;
owl:disjointWith SAO:1546288504,
SAO:1682692988,
SAO:1686050947,
SAO:2019617624 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao113580911"^^xsd:string .
SAO:118541872 a owl:Class ;
rdfs:label "Gap Junction"^^xsd:string ;
skos:prefLabel "Gap Junction"^^xsd:string ;
skos:definition "Any specialized areas of the plasma membranes of adjacent cells where the membranes are 2-4 nm apart and penetrated by a connexon (Gene Ontology)."^^xsd:string ;
rdfs:subClassOf SAO:1922892319 ;
owl:disjointWith SAO:427941916,
SAO:946766835,
SAO:1400623473,
SAO:1939999134,
SAO:1956738165 ;
NIFRID:gene_Ontology_ID "0005921"^^xsd:string ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao118541872"^^xsd:string ;
NIFRID:umls_ID "C0206117"^^xsd:string ;
skos:example <http://ccdb.ucsd.edu/SAO/images/gap_junction_sw_512x512.jpg> .
SAO:118944228 a owl:Class ;
rdfs:label "Mitochondrial Intermembrane Space"^^xsd:string ;
skos:prefLabel "Mitochondrial Intermembrane Space"^^xsd:string ;
skos:definition "The region between the inner and outer lipid bilayers of the mitochondrial envelope. (Gene Ontology)."^^xsd:string ;
rdfs:subClassOf SAO:343550527 ;
owl:disjointWith SAO:508958414,
SAO:1899375636 ;
rdfs:comment "I'm having difficulty deciding whether this is a regional part of a mitochondrion or whether it is a site; today it is a regional part."^^xsd:string ;
NIFRID:gene_Ontology_ID "0005758"^^xsd:string ;
NIFRID:hasCurationStatus NIFRID:graph_position_temporary ;
NIFRID:sao_ID "sao118944228"^^xsd:string ;
NIFRID:umls_ID "C1166886"^^xsd:string .
SAO:120573470 a owl:Class ;
rdfs:label "Cellular Inclusion"^^xsd:string ;
skos:prefLabel "Cellular Inclusion"^^xsd:string ;
NIFRID:synonym "Inclusion Body"^^xsd:string ;
skos:definition "A nuclear or cytoplasmic aggregate of stainable substances, usually proteins."^^xsd:string ;
rdfs:subClassOf SAO:1337158144 ;
owl:disjointWith SAO:221389602,
SAO:628508602,
SAO:730872736,
SAO:787716553,
SAO:830981606,
SAO:1231384859,
SAO:1397492660,
SAO:1539965131,
SAO:1635329413,
SAO:1663586795,
SAO:1784069613,
SAO:1938587839,
SAO:1969557946 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao120573470"^^xsd:string .
SAO:120818728 a owl:Class ;
rdfs:label "Lumenal Surface"^^xsd:string ;
skos:prefLabel "Lumenal Surface"^^xsd:string ;
rdfs:subClassOf SAO:1329750433 ;
owl:disjointWith SAO:1514682949,
SAO:2135015805 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao120818728"^^xsd:string .
SAO:124393998 a owl:Class ;
rdfs:label "Endoplasmic Reticulum Exit Site"^^xsd:string ;
skos:prefLabel "Endoplasmic Reticulum Exit Site"^^xsd:string ;
skos:definition "Specialized ribosome-free subdomains of synthetic endoplasmic reticulum where cargo is concentrated into vesicles tha bud from the endoplasmic reticulum for tranport to the Golgi (Horton and Ehlers, 2004)."^^xsd:string ;
rdfs:subClassOf SAO:2019617624 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao124393998"^^xsd:string .
SAO:128470897 a owl:Class ;
rdfs:label "Sub-surface Cisternae"^^xsd:string ;
skos:prefLabel "Sub-surface Cisternae"^^xsd:string ;
skos:definition "Specialization of the hypolemmal cisterna consisting of either single profiles or closely apposed stacks of ER in which the lumen is obliterated, lying 10-20 nm beneath the plasma membrane (Peters, Palay and Webster, 1991)."^^xsd:string ;
rdfs:subClassOf SAO:1634374950 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao128470897"^^xsd:string ;
skos:example <http://ccdb.ucsd.edu/SAO/images/cisternae_sw_512x512.jpg> .
SAO:138219748 a owl:Class ;
rdfs:label "Vesicular Component"^^xsd:string ;
skos:prefLabel "Vesicular Component"^^xsd:string ;
rdfs:subClassOf SAO:1546288504 ;
owl:disjointWith SAO:9456487,
SAO:632188024 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao138219748"^^xsd:string .
SAO:138430598 a owl:Class ;
rdfs:label "Nematosome"^^xsd:string ;
skos:prefLabel "Nematosome"^^xsd:string ;
skos:definition "Cellular inclusions found in cytoplasm that resemble nuclioli and stain with basophilic stains. They are ball-like structures about .9 microns in diameter and lack a limiting membrane. Structurally, they are composed of tightly packed fine filaments attached to them by means of fine filaments that radiate from their periphery. They were first discribed by Grillo in 1970. (from Peters, Palay, Webster)"^^xsd:string ;
rdfs:subClassOf SAO:120573470 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao138430598"^^xsd:string .
SAO:172297168 a owl:Class ;
rdfs:label "Dendritic Tree"^^xsd:string ;
skos:prefLabel "Dendritic Tree"^^xsd:string ;
skos:definition "The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches."^^xsd:string ;
rdfs:subClassOf SAO:1970895398 ;
owl:disjointWith SAO:2128156969 ;
NIFRID:bonfireID "BF_C000102"^^xsd:string ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao172297168"^^xsd:string .
SAO:180601769 a owl:Class ;
rdfs:label "Cytoplasmic Vesicle"^^xsd:string ;
skos:prefLabel "Cytoplasmic Vesicle"^^xsd:string ;
skos:definition "A vesicle formed of membrane or protein, found in the cytoplasm of a cell (Gene Ontology)."^^xsd:string ;
rdfs:subClassOf SAO:221389602 ;
NIFRID:gene_Ontology_ID "0031410"^^xsd:string ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao180601769"^^xsd:string .
SAO:181458425 a owl:Class ;
rdfs:label "Glial Limiting Endfoot"^^xsd:string ;
skos:prefLabel "Glial Limiting Endfoot"^^xsd:string ;
skos:definition "Process of astrocyte that extends to the surface of the central nervous system. Together, they form the glial limiting membrane or glial limitans."^^xsd:string ;
rdfs:subClassOf SAO:388182739 ;
owl:disjointWith SAO:2048701763 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao181458425"^^xsd:string .
SAO:183270081 a owl:Class ;
rdfs:label "Subregional Part Of Neuron Process"^^xsd:string ;
skos:prefLabel "Subregional Part Of Neuron Process"^^xsd:string ;
skos:definition "Subcompartment of a compartment."^^xsd:string ;
rdfs:subClassOf SAO:420949334 ;
owl:disjointWith SAO:280355188,
SAO:420754792 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao183270081"^^xsd:string .
SAO:187426937 a owl:Class ;
rdfs:label "Synaptic Bouton"^^xsd:string ;
skos:prefLabel "Synaptic Bouton"^^xsd:string ;
skos:definition "Terminal pre-synaptic ending of an axon or axon collateral."^^xsd:string ;
rdfs:subClassOf SAO:2007137787 ;
owl:disjointWith SAO:488120195 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao187426937"^^xsd:string ;
skos:example <http://ccdb.ucsd.edu/SAO/images/syn_bouton_sw_512x512.jpg> .
SAO:188049490 a owl:Class ;
rdfs:label "Node Of Ranvier Axon"^^xsd:string ;
skos:prefLabel "Node Of Ranvier Axon"^^xsd:string ;
skos:definition "Part of axon located at the gaps between adjacent myelin sheaths characterized by a slightly larger diameter than paranodal axon and the presence of a dense coating on the axolemma."^^xsd:string ;
rdfs:subClassOf SAO:340271629 ;
owl:disjointWith SAO:830092290,
SAO:936144858 ;
NIFRID:modifiedDate "May 28, 2009"^^xsd:string ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:hasFormerParentClass SAO:1791490892 ;
NIFRID:sao_ID "sao-188049490"^^xsd:string .
SAO:195217619 a owl:Class ;
rdfs:label "Regional Part Of Schwann Cell"^^xsd:string ;
skos:prefLabel "Regional Part Of Schwann Cell"^^xsd:string ;
rdfs:subClassOf SAO:895885284 ;
owl:disjointWith SAO:685712019,
SAO:831502550 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao195217619"^^xsd:string .
SAO:203987954 a owl:Class ;
rdfs:label "Axonal Growth Cone"^^xsd:string ;
skos:prefLabel "Axonal Growth Cone"^^xsd:string ;
rdfs:subClassOf SAO:280355188 ;
owl:disjointWith SAO:256000789,
SAO:627227260 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao203987954"^^xsd:string .
SAO:205380252 a owl:Class ;
rdfs:label "Neuropil"^^xsd:string ;
skos:prefLabel "Neuropil"^^xsd:string ;
skos:definition "A dense intricate feltwork of interwoven fine glial processes, fibrils, synaptic terminals, axons, and dendrites interspersed among the nerve cells in the gray matter of the central nervous system (MSH)."^^xsd:string ;
rdfs:subClassOf SAO:508165343 ;
owl:disjointWith SAO:732341560 ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao205380252"^^xsd:string ;
NIFRID:umls_ID "C0228081"^^xsd:string ;
skos:example <http://ccdb.ucsd.edu/SAO/images/neuropil_sw_512x512.jpg> .
SAO:206157942 a owl:Class ;
rdfs:label "Internode"^^xsd:string ;
skos:prefLabel "Internode"^^xsd:string ;
skos:definition "Part of nodal complex located underneath the compact myelin in between nodes of Ranvier"^^xsd:string ;
rdfs:subClassOf SAO:596411490 ;
NIFRID:sao_ID "sao-206157942"^^xsd:string .
SAO:220861693 a owl:Class ;
rdfs:label "Nuclear Pore"^^xsd:string ;
skos:prefLabel "Nuclear Pore"^^xsd:string ;
skos:definition "Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined (Gene Ontology)."^^xsd:string ;
rdfs:subClassOf SAO:1499850686 ;
owl:disjointWith SAO:505137457,
SAO:661522542 ;
NIFRID:gene_Ontology_ID "0005643"^^xsd:string ;
NIFRID:hasCurationStatus NIFRID:uncurated ;
NIFRID:sao_ID "sao220861693"^^xsd:string ;
NIFRID:umls_ID "C0028587"^^xsd:string ;
skos:example <http://ccdb.ucsd.edu/SAO/images/nucl_pore_2_sw_512x512.jpg>,
<http://ccdb.ucsd.edu/SAO/images/nucl_pore_sw_512x512.jpg> .