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Reference for ASCAT required even when not calling with ASCAT #754

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ggabernet opened this issue Mar 12, 2019 · 2 comments
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Reference for ASCAT required even when not calling with ASCAT #754

ggabernet opened this issue Mar 12, 2019 · 2 comments

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@ggabernet
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ggabernet commented Mar 12, 2019

Hi Maxime, thank you for incorporating ASCAT to the toolset of Sarek, it will be very useful for CNV analysis!
However, I have the issue now that when executing the somatic VC procedure, even when ascat is not used, it requires the ascat reference:

Launching `scilifelab/Sarek` [amazing_goldberg] - revision: a4ed8f34dc [2.3.FIX1]
WARN: There's no process matching config selector: MapReads
Missing references: acLociGC /sfs/4/qbic/references/human/1000G_phase3_20130502_SNP_maf0.3.loci.gc
ERROR ~ Missing Reference file(s), see --help for more information

The command executed was:

nextflow run scilifelab/Sarek/somaticVC.nf -r 2.3.FIX1 --sample Preprocessing/Recalibrated/recalibrated.tsv -profile cfc --genome GRCh37 --tools strelka -resume

Would it be possible to only check for this reference file if the tool ASCAT is used for calling?

@maxulysse
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That's a very good point.
I'll look into it.

@ggabernet
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thank you!

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