Bias-free Footprint Enrichment Test (BiFET) is a statistical method to identify transcription factors (TFs) whose footprints are over-represented in target regions compared to background regions after correcting for differences in read counts and GC contents between target and background regions, where regions represent ATAC-seq or DNAse-seq peaks.
To install this package, start R and enter:
if (!requireNamespace("BiocManager", quietly=TRUE))
Alternatively, the most updated version of this package may be installed via the commands in R:
For more details about BiFET, please read our publication in Nucleic Acids Research: https://www.ncbi.nlm.nih.gov/pubmed/30428075
For instructions on how to use BiFET, please see the package vignette: https://bioconductor.org/packages/release/bioc/vignettes/BiFET/inst/doc/BiFET.html
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