This repository contains codes for generating the mathematical models and plots for the manuscript: "Dominance vs. epistasis: the biophysical origins and plasticity of genetic interactions within and between alleles"
* Correspondence: bl11@sanger.ac.uk and xl5@sanger.ac.uk
The codes can be run in the order of: "1-Function.R", "2-Parameter_and_WT.R","3-Make_dataframe.R","4-Figure.R".
It contains the mathematical models involved in this project.
It contains the parameters applied to the models.
It contains all the codes to simulate and generate data frames for plotting the data. This code also includes the functions and parameters defined in "Function.R" and "Parameter_and_WT.R" for a quick analysis.
It contains all the code used to generate figures. If you have successfully unzipped the "All_model.Rdata", you don't need to run "3-Make_dataframe.R" for waiting a long time to generate data. You can directly run "4-Figure.R" to generate pictures.