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Update deepsea.rst
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aaronkw committed Dec 2, 2019
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Expand Up @@ -44,10 +44,13 @@ We support three types of input: vcf, fasta, bed. If you want to predict effects

**Bed format** provides another way to specify sequences in human reference genome (hg19). The bed input should specify 1000bp-length regions. A minimal example is ``chr1 109817091 109818090``. The three columns are chromosome, start position, and end position.

We recommend using the web server if you have <10,000 variants or sequences. You will experience degraded performance when submitting a larger set of sequeneces. In those instances, we suggest that you split the set into multiple <10,000 submissions, or run the standalone version on your local machine, or contact our group directy.

Genome coordinates
~~~~~~~~~~~~
We support only ``GRCh37/hg19`` genome coordinates. You can use LiftOver to convert your coordinates to the correct version.

Large submissions
~~~~~~~~~~~~
We recommend using the web server if you have <10,000 variants or sequences. You will experience degraded performance when submitting a larger set of sequeneces. In those instances, we suggest that you split the set into multiple <10,000 submissions, or run the standalone version on your local machine, or contact our group directy.

In-silico mutagenesis
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