Protrusion/retraction signal enrichment and protrusion-retraction cycle duration analysis according to Nanda et al.
Related to: Nanda S., Calderon A., Duong T-T., Koch J., Sachan A., Xin X., Solouk D., Wu Y-W., Nalbant P., Dehmelt L., Crosstalk between Rac and Rho GTPase activity mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cycles.
This repository contains the code to perform the Protrusion/retraction signal enrichment and protrusion-retraction cycle duration analysis described in Nanda et al. and an example dataset.
A detailed protocol for installing and running the analysis using the example data set is provided here:
Optional: The modified ADAPT plugin that was used in Nanda et al. is availabel here:
https://github.com/agdehmelt/adapt_edge_analysis_modification