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kronrlsmkl

Matlab implementation of the Kronecker Regularized Least Squares with multiple kernels algorithm.

Usage

Drug-target information should be represented in adjacency matrix format, and drug and target kernels are represented as 3D-matrices, where the third dimension refers to each kernel.

Data matrices can be downloaded from http://www.cin.ufpe.br/~acan/kronrlsmkl/

Please cite:

Nascimento, André CA, Ricardo BC Prudêncio, and Ivan G. Costa. "A multiple kernel learning algorithm for drug-target interaction prediction." BMC Bioinformatics 17, no. 1 (2016): 1. URL: http://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-016-0890-3

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Kronecker Regularized Least Squares with multiple kernels

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