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.. _fMRI_04_Preprocessing.rst | ||
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fMRI Tutorial #4: Preprocessing | ||
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Overview | ||
------------- | ||
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Now that we're familiar with where our data is located and what it looks like, we will do the first step of fMRI analysis: **Preprocessing**. | ||
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Think of preprocessing as cleaning up images. When you take a photo with a camera, for example, there are several things you can do to make the image look better: | ||
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* Remove red eye; | ||
* Increase color saturation; | ||
* Remove shadows. | ||
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Similarly, when we preprocess fMRI data we are cleaning up the 3-dimensional images that we acquire every TR. | ||
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Preprocessing Steps | ||
-------------- | ||
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The major preprocessing steps are: | ||
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* Brain extraction (or "skull stripping") | ||
* Motion correction | ||
* Slice timing correction | ||
* Smoothing | ||
* Temporal Filtering | ||
* Registration | ||
* Normalization | ||
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Different software packages will do these steps in slightly different order - for example, FSL will do normalization after the statistical model has been fit. There are also some analyses which omit certain steps - for example, people who do multi-voxel pattern analyses sometimes will not do smoothing. In any case, these represent the most common steps that are performed on a typical dataset. |