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Merfin v1.1

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@arangrhie arangrhie released this 02 Dec 23:40

Polishing modes added that does not use k* (reference is partially from the same individual as the reads, or reference vs. read copy numbers are not expected to match).

  • filter variant calls for polishing
    • Reference is from the same individual: -polish (uses k*)
    • Reference is partially from the same individual, or copy-number estimates are unstable. This mode disables k*.
      • -better: Almost identical to -polish, with k* disabled (deprecated)
      • -loose : Remove variants only when the num. missing (error) k-mers increase. Neutral alternate paths that score equally to the reference path are included.
      • -strict: Include variants only when the num. missing (error) k-mers decrease. Neutral alternative paths that score equally to the reference path are excluded