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focused-MR

"Selecting invalid instruments to improve Mendelian randomization with two-sample summary data" by Ashish Patel, Francis J. DiTraglia, Verena Zuber, and Stephen Burgess

Paper link: https://arxiv.org/pdf/2107.01513.pdf (forthcoming Annals of Applied Statistics)

  • R code to run the method: focusedMR.R

  • CETP-analysis.R: R script to run the CETP cis-MR data example from the paper

  • PCSK9-analysis.R: R script to run the PCSK9 cis-MR data example from the paper

  • vitaminD-analysis.R: R script to run the vitamin D data example from the paper

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R code to reproduce results of data examples in 'Selecting invalid instruments to improve MR with two-sample summary data''

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