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fixed links for additional reading
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avrilcoghlan committed Mar 2, 2013
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Expand Up @@ -968,9 +968,7 @@ additional R packages:
Links and Further Reading
-------------------------

Some links are included here for further reading, which will be
especially useful if you need to use the R package for your project
or assignments.
Some links are included here for further reading.

For background reading on graphs and protein-protein interaction
graphs, it is recommended to read Chapters 1, 2 and 4 of
Expand Down Expand Up @@ -1017,7 +1015,7 @@ Robert Gentleman and Seth Falcon
Acknowledgements
----------------

Many of the ideas for the examples and exercies for this practical
Many of the ideas for the examples and exercises for this practical
were inspired by the book
*Principles of Computational Cell Biology: from protein complexes to cellular networks*
by Volkhard Helms (Wiley-VCH;
Expand Down Expand Up @@ -1047,7 +1045,7 @@ Q1. de Lichtenberg *et al* identified protein-protein complexes in the yeast *Sa
Is this the same as the number of vertices in the graph of de
Lichtenberg *et al*'s data? If not, can you explain why?
Note: the full paper by de Lichtenberg *et al* is available at
`http://www.sciencemag.org/cgi/content/full/sci;307/5710/724 <http://www.sciencemag.org/cgi/content/full/sci;307/5710/724>`_
`http://www.sciencemag.org/content/307/5710/724.abstract <http://www.sciencemag.org/content/307/5710/724.abstract>`_
Q2. What is the minimum, maximum and mean number of interactions for the proteins in the graph of de Lichtenberg *et al*'s data?
Can you find an example of a *hub protein*?
Make a histogram plot of the number of interactions for the
Expand Down Expand Up @@ -1076,7 +1074,7 @@ Q5. What proteins does yeast protein YPR119W interact with, in de Lichtenberg *e
(`www.yeastgenome.org/ <http://www.yeastgenome.org/>`_). It may
also be useful to look at Figure 3 in de Lichtenberg *et al*'s
paper
(`http://www.sciencemag.org/cgi/content/full/sci;307/5710/724 <http://www.sciencemag.org/cgi/content/full/sci;307/5710/724>`_).
(`http://www.sciencemag.org/content/307/5710/724.abstract <http://www.sciencemag.org/content/307/5710/724.abstract>`_).
Can you identify the complex(es) that YPR119W belongs to in Figure
1 of de Lichtenberg *et al*'s paper?

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