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A tool for assembling, searching and classifying B-cell epitopes

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Epibuilder

A tool for assembling, searching and classifying B-cell epitopes

Available at https://sourceforge.net/projects/epibuilder/

Please cite us:

Moreira RS, Filho VB, Calomeno NA, Wagner G, Miletti LC. EpiBuilder: A Tool for Assembling, Searching, and Classifying B-Cell Epitopes. Bioinform Biol Insights. 2022;16:117793222210952. doi: https://doi.org/10.1177/11779322221095221


Also cite epitope prediction methods:

Jespersen, MC, Peters, B, Nielsen, M, Marcatili, P. BepiPred-2.0: improving sequence-based B-cell epitope prediction using conformational epitopes. Nucleic Acids Res. 2017;45:W24-W29.

Chou, PY, Fasman, GD. Prediction of the secondary structure of proteins from their amino acid sequence. Adv Enzymol Relat Areas Mol Biol. 2006;47:45-148.

Emini, EA, Hughes, JV, Perlow, DS, Boger, J. Induction of hepatitis A virus-neutralizing antibody by a virus-specific synthetic peptide. J Virol. 1985;55:836-839.

Karplus, PA, Schulz, GE. Prediction of chain flexibility in proteins — a tool for the selection of peptide antigens. Naturwissenschaften. 1985;72:212-213.

Kolaskar, AS, Tongaonkar, PC. A semi-empirical method for prediction of antigenic determinants on protein antigens. FEBS Lett. 1990;276:172-174.

Parker, JMR, Guo, D, Hodges, RS. New hydrophilicity scale derived from high-performance liquid chromatography peptide retention data: correlation of predicted surface residues with antigenicity and X-ray-derived accessible sites. Biochemistry. 1986;25:5425-5432.

And Blastp Algorithm, if used.

Camacho, C., Coulouris, G., Avagyan, V. et al. BLAST+: architecture and applications. BMC Bioinformatics 10, 421 (2009). https://doi.org/10.1186/1471-2105-10-421

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