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fixes #942, fixes #940, fixes #939 #992

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9 changes: 8 additions & 1 deletion biolink-model.yaml
Expand Up @@ -2124,6 +2124,7 @@ slots:
- SIO:001331 # diagnosis
exact_mappings:
- DrugCentral:5271
- SEMMEDDB:diagnoses

is diagnosed by:
is_a: related to at instance level
Expand Down Expand Up @@ -4892,7 +4893,6 @@ slots:
- NCIT:genetic_biomarker_related_to
- NCIT:is_molecular_abnormality_of_disease
- ORPHA:465410
- SEMMEDDB:diagnoses

# It may be helpful to introduce an intermediate predicate in between 'related_to' and 'expressed in'
# which would have a domain of 'biological entity' and range of 'anatomical entity', to map predicates
Expand Down Expand Up @@ -5073,10 +5073,14 @@ slots:
- SNOMED:has_finding_site
- SNOMED:has_indirect_procedure_site
- SNOMED:has_inherent_location
domain: named thing
range: named thing

location of:
is_a: related to at instance level
aliases: ['site of']
domain: named thing
range: named thing
description: >-
holds between material entity or site and a material entity
that is located within it (but not considered a part of it)
Expand Down Expand Up @@ -7933,6 +7937,9 @@ classes:
- UMLS
close_mappings:
- dcid:ChemicalCompound
narrow_mappings:
- NCIT:C20401 # monoclonal antibody
- SNOMEDCT:49616005 # monoclonal antibody (substance)

nucleic acid entity:
is_a: molecular entity
Expand Down