Skip to content

braindynamicslab/w3c

Repository files navigation

W3C Model: The Wong-Wang-Wilson-Cowan hybrid model.

This model takes the form of

   dS_i,E/dt = - S_i,E/tau_E + (1-S_i,E) * gamma_E * H_E(w_EE.*S_i,E - w_IE.*S_i,I + I_E + I_i,G)
   dS_i,I/dt = - S_i,I/tau_I + (1-S_i,I) * gamma_I * H_I(w_EI.*S_i,E - w_II.*S_i,I + I_I)
 
 where the global input
   I_i,G = G * sum_j [C_ij*S_i,E] where C_ij = 0 for i=j
 
 and the transfer function
   H_p(x) = (r_max + (a_p*x-b_p-r_max) / (1-exp(d_p * (a_p*x - b_p - r_max))) )/ (1-exp(-d_p*(a_p*x-b_p)))
 
 for p=E or I.
 

The model can be thought of as a high-dimensional generalization of Wong-Wang model which is more consistent with the form of the Wilson-Cowan model. Importantly, the model use a sigmoidal transfer function that matches the linear threshold transfer function as used in Wong-Wang (2006)/Deco et al (2014JON) asymptotically for lower level of of activity. Note that sigmoidal transfer function will cap the firing rate such that the model is more realistic.

You can explore the global bifurcation using the file bifurcation_global_model.m, which systematically study the bifurcation of the global W3C model. However, please note that this program could take more than a week to run. If you simply want to get the gist of the computation of bifurcation diagrams, please see the computation for the local model.

Please cite this paper if you use this code: Zhang, Mengsen, Yinming Sun, and Manish Saggar. "Cross-attractor repertoire provides new perspective on structure-function relationship in the brain." NeuroImage 259 (2022): 119401. https://doi.org/10.1016/j.neuroimage.2022.119401

About

No description, website, or topics provided.

Resources

Stars

Watchers

Forks

Releases

No releases published

Packages

No packages published

Languages