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Hi Federico,
I had a problem with the gui on linux that I thought depended on Pyqt5 being installed via conda, you can see the bug down here. All the meshes with an alpha different than 1 disappear. It turns out it is a vtk problem and the solution here solves the problem.
Adding these two lines doesn't seem to change anything on my mac, didn't test it on windows though.
(the two lines has to be placed before the import of QVTKRenderWindowInteractor)
brainrender/brainrender/gui/app.py
Line 6 in c9dc513
Screen.Recording.2022-01-03.at.19.10.16.mov