Protocols for Decentralized Exchange

Protocol	Asset(s)	Blockchain(s)	Status	Notes
0x	ERC20 Tokens	Ethereum	Live on Ethereum mainnet	Open protocol. Generic exchange of ERC20 with off-chain relayers.
AirSwap
Bancor	ERC20 Tokens	Ethereum	Live on Ethereum mainnet	Open protocol. On-chain exchange and pricing.
Bisq	All	Bitcoin	Live	Generic exchange for cryptocurrencies.
Bitshares	Bitshares, Bitshares SmartCoins[3]	Bitshares	Live on Bitshares mainnet	Open protocol. Bitshares created a DEX on top of their blockchain. Other DEX's for Bitshares also exist.
CDX	All	Ethereum, Youdex Sidechain	Proposed	Open protocol. Coin direct exchange, cross-chain atomic swap.
COMIT	All[2]	All[2]	Proposed	Open protocol. Off-chain. Utilizes state channels & 3rd party liquidity providers.
COSMOS
Counterparty	Bitcoin, Counterparty Tokens	Bitcoin	Live on Bitcoin mainnet	Open protocol. Counterparty extends Bitcoin by adding metadata to Bitcoin transactions.
DEAL	NEO Assets[6]	NEO	Under development	Closed protocol[6]. Implemented as smart contracts on the NEO blockchain.
Decred
Dharma	ERC20 Tokens, Dharma Debt Token	Ethereum	Under development	Open protocol. Debt contracts.
Dydx	ERC20 Tokens, Dydx Derivatives (Option, Short Sell)	Ethereum	Under development	Open protocol. Derivatives contracts, uses 0x.
Enigma	All[2]	All[2]	Proposed	The Engima team is working on many projects. A protocol for decentralized exchanged was proposed in one of their papers.
Exchange Union	All[9]	All[9]	Under development	Open protocol. Off-chain payment/state channels using cross-chain atomic swaps. Decentralized order propagation.
Komodo	N/A	Komodo	Under development	Closed protocol. Leverages cross chain atomic swaps[4].
Kyber Network	ERC20 Tokens	Ethereum	Live on Ethereum mainnet	Closed protocol. Kyber is two things: a product for exchanging, and smart contracts used by that exchange. Only Kyber can use the contracts.
Lendroid	ERC20 Tokens	Ethereum	Under development	Open protocol. Margin Loans.
Gemini
MARKET Protocol	Derivatives	Ethereum	Under development	Open protocol. Cross Chain and real world assets.
Melon	ERC20 Tokens, Melon Fund Shares[5]	Ethereum	Live on Ethereum mainnet	Open protocol. A protocol for creating an investment fund that holds an arbitrary number of underlying ERC20 tokens.
OmiseGo	All[1]	All[1]	Under development	Open protocol. A blockchain with built-in support for decentralized exchange.
Radar Relay
Raiden Network	ERC20 Tokens	Ethereum	Under development	Off-chain ERC20 token exchange. Similar to Lightning Network for Bitcoin.
Republic	ERC20 Tokens, Ether, Bitcoin	Ethereum, Bitcoin	Under development	Open protocol. Trustless cross-chain atomic trading of Ether, ERC20 tokens and Bitcoin pairs
Ripple	XRP, Ripple Issued Currencies	Ripple	Live on Ripple mainnet	Open protocol. Ripple has builtin transaction types such as Offer Create[8] that allow anyone to trustlessly exchange Ripple based assets.
Saturn	ERC20 Tokens, ERC223 Tokens	Ethereum	Under development	Open protocol. The team building this already built a dex called Radex, that uses a closed protocol. Saturn is a generalization of Radex protocol.
Set	ERC20 Tokens, Set Tokens	Ethereum	Under development	Open protocol. Token abstraction.
Snowglobe	ERC20 Tokens	Ethereum	Under development	Open protocol. Shared order book and liquidity.
Stellar	Stellar Assets	Stellar	Live on Stellar mainnet	Open protocol. The Stellar blockchain scripting language has builtins for decentralized exchange[7].
Swap	ERC20 Tokens	Ethereum	Under development	Closed protocol. Plans to become an open protocol.
TPL	TBC	TBC	Proof of concept
WandX	ERC20 Tokens, ERC20 Token Baskets	Ethereum	Under development	Closed protocol.
Waves
Wyvern	Nonfungible Ethereum assets	Ethereum	Live on Ethereum mainnet	Open protocol. Generic exchange of nonfungible Ethereum assets with off-chain orderbooks.