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updated screenshots, replaced 'n/a' with blank cell
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Rajat-Sirohi committed Jun 15, 2021
1 parent 4ef144e commit 9c310d6
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38 changes: 38 additions & 0 deletions src/pages/resultsView/ResultsViewPageStore.ts
Expand Up @@ -1143,6 +1143,26 @@ export class ResultsViewPageStore {
},
});

// TODO: Should include all clinical attributes, not just server attributes
readonly mutationsTabClinicalAttributes = remoteData<ClinicalAttribute[]>({
await: () => [this.studyIds],
invoke: async () => {
const clinicalAttributes = await client.fetchClinicalAttributesUsingPOST(
{
studyIds: this.studyIds.result!,
}
);
const excludeList = ['CANCER_TYPE_DETAILED', 'MUTATION_COUNT'];

return _.uniqBy(
clinicalAttributes.filter(
x => !excludeList.includes(x.clinicalAttributeId)
),
x => x.clinicalAttributeId
);
},
});

readonly clinicalAttributeIdToClinicalAttribute = remoteData({
await: () => [this.clinicalAttributes],
invoke: () =>
Expand Down Expand Up @@ -1255,6 +1275,22 @@ export class ResultsViewPageStore {
},
});

readonly clinicalAttributeIdToAvailableFrequency = remoteData({
await: () => [
this.clinicalAttributeIdToAvailableSampleCount,
this.samples,
],
invoke: () => {
const numSamples = this.samples.result!.length;
return Promise.resolve(
_.mapValues(
this.clinicalAttributeIdToAvailableSampleCount.result!,
count => (100 * count) / numSamples
)
);
},
});

readonly cnSegments = remoteData<CopyNumberSeg[]>(
{
await: () => [this.filteredSamples],
Expand Down Expand Up @@ -3442,6 +3478,8 @@ export class ResultsViewPageStore {
this.uniqueSampleKeyToTumorType.result!,
this.generateGenomeNexusHgvsgUrl,
this.clinicalDataGroupedBySampleMap,
this.mutationsTabClinicalAttributes,
this.clinicalAttributeIdToAvailableFrequency,
this.genomeNexusClient,
this.genomeNexusInternalClient,
() => this.urlWrapper.query.mutations_transcript_id
Expand Down
265 changes: 265 additions & 0 deletions src/pages/resultsView/mutation/AddColumns.tsx
@@ -0,0 +1,265 @@
import * as React from 'react';
import * as _ from 'lodash';
import MobxPromise from 'mobxpromise';
import { observer } from 'mobx-react';
import { action, computed, makeObservable, observable } from 'mobx';
import { Checkbox } from 'react-bootstrap';
import { remoteData, getTextWidth } from 'cbioportal-frontend-commons';
import { ClinicalAttribute } from 'cbioportal-ts-api-client';
import { IColumnVisibilityControlsProps } from 'shared/components/columnVisibilityControls/ColumnVisibilityControls';
import { MSKTab, MSKTabs } from 'shared/components/MSKTabs/MSKTabs';
import CustomDropdown from 'shared/components/oncoprint/controls/CustomDropdown';
import AddChartByType from '../../studyView/addChartButton/addChartByType/AddChartByType';
import { ChartDataCountSet } from '../../studyView/StudyViewUtils';

export interface IAddColumnsProps extends IColumnVisibilityControlsProps {
clinicalAttributes: ClinicalAttribute[];
clinicalAttributeIdToAvailableFrequency: MobxPromise<{
[clinicalAttributeId: string]: number;
}>;
}

enum Tab {
MUTATIONS = 'Mutations',
CLINICAL = 'Clinical',
}

type Option = {
key: string;
label: string;
selected: boolean;
};

// Copied these constants from oncoprint/AddTracks.tsx
// since importing them results in errors during testing
// due to a separate import in that file.
const MIN_DROPDOWN_WIDTH = 400;
const CONTAINER_PADDING_WIDTH = 20;
const TAB_PADDING_WIDTH = 14;
const COUNT_PADDING_WIDTH = 17;
@observer
export default class AddColumns extends React.Component<IAddColumnsProps, {}> {
@observable tabId: Tab = Tab.MUTATIONS;

constructor(props: IAddColumnsProps) {
super(props);
makeObservable(this);
}

@action.bound
private updateTabId(newId: Tab) {
this.tabId = newId;
}

@action.bound
private addAll(ids: string[], options: Option[] | undefined) {
if (this.props.onColumnToggled && options) {
for (let option of options) {
if (!option.selected && ids.includes(option.key)) {
this.props.onColumnToggled(option.key);
}
}
}
}

@action.bound
private clearAll(ids: string[], options: Option[] | undefined) {
if (this.props.onColumnToggled && options) {
for (let option of options) {
if (option.selected && ids.includes(option.key)) {
this.props.onColumnToggled(option.key);
}
}
}
}

@action.bound
private toggle(id: string) {
if (this.props.onColumnToggled && id) {
this.props.onColumnToggled(id);
}
}

readonly emptyPromise = remoteData({
invoke: () =>
new Promise<ChartDataCountSet>(() => {
return;
}),
});

@computed get clinicalAttributeIds(): Set<string> {
let ids: Set<string> = new Set();
this.props.clinicalAttributes.forEach(x =>
ids.add(x.clinicalAttributeId)
);
return ids
.add('CANCER_STUDY')
.add('CANCER_TYPE_DETAILED')
.add('MUTATION_COUNT');
}

@computed get mutationsOptions(): Option[] | undefined {
return this.props.columnVisibility
?.filter(col => !this.clinicalAttributeIds.has(col.id))
.map(col => ({
key: col.id,
label: col.name,
selected: col.visible,
}));
}

@computed get mutationsTabContent() {
return (
<div>
{this.mutationsOptions && (
<AddChartByType
options={this.mutationsOptions}
freqPromise={this.emptyPromise}
onAddAll={(ids: string[]) =>
this.addAll(ids, this.mutationsOptions)
}
onClearAll={(ids: string[]) =>
this.clearAll(ids, this.mutationsOptions)
}
onToggleOption={this.toggle}
optionsGivenInSortedOrder={true}
width={this.dropdownWidth}
excludeFrequency={true}
/>
)}
</div>
);
}

@computed get clinicalOptions(): Option[] | undefined {
if (!this.props.columnVisibility) return undefined;

return this.props.columnVisibility
.filter(col => this.clinicalAttributeIds.has(col.id))
.map(col => ({
key: col.id,
label: col.name,
selected: col.visible,
}));
}

@computed get clinicalTabContent() {
return (
<div>
{this.props.columnVisibility && this.clinicalOptions && (
<AddChartByType
options={this.clinicalOptions}
freqPromise={
this.props.clinicalAttributeIdToAvailableFrequency
}
onAddAll={(ids: string[]) =>
this.addAll(ids, this.clinicalOptions)
}
onClearAll={(ids: string[]) =>
this.clearAll(ids, this.clinicalOptions)
}
onToggleOption={this.toggle}
optionsGivenInSortedOrder={false}
width={this.dropdownWidth}
/>
)}
</div>
);
}

@computed get mutationsTabText() {
return (
<div>
{Tab.MUTATIONS}
<span style={{ paddingLeft: 5 }}>
<span className="oncoprintDropdownCount">
{this.mutationsOptions?.length}
</span>
</span>
</div>
);
}

@computed get clinicalTabText() {
return (
<div>
{Tab.CLINICAL}
<span style={{ paddingLeft: 5 }}>
<span className="oncoprintDropdownCount">
{this.clinicalOptions?.length}
</span>
</span>
</div>
);
}

private getTextPixel(text: string | undefined, fontSize: string) {
// This is a very specified function to calculate the text length in Add Tracks dropdown
const FRONT_FAMILY = 'Helvetica Neue';
return Math.floor(
getTextWidth(text ? text : '', FRONT_FAMILY, fontSize)
);
}

@computed get dropdownWidth() {
let width = 2 * CONTAINER_PADDING_WIDTH;
const HEADER_FONT_SIZE = '14px';
const COUNT_FONT_SIZE = '11px';

const textWidth =
this.getTextPixel(Tab.CLINICAL, HEADER_FONT_SIZE) +
TAB_PADDING_WIDTH;
const countTextWidth =
this.getTextPixel(
this.clinicalOptions?.length.toString(),
COUNT_FONT_SIZE
) + COUNT_PADDING_WIDTH;
width += textWidth + countTextWidth;

return Math.max(width, MIN_DROPDOWN_WIDTH);
}

render() {
return (
<div style={{ float: 'right' }}>
<CustomDropdown
bsStyle="default"
title="Columns"
id="addColumnsDropdown"
className={this.props.className}
styles={{ minWidth: MIN_DROPDOWN_WIDTH, width: 'auto' }}
buttonClassName="btn btn-default btn-sm"
>
<div
style={{
display: 'flex',
flexDirection: 'column',
}}
>
<MSKTabs
activeTabId={this.tabId}
onTabClick={this.updateTabId}
unmountOnHide={false}
className="mainTabs mutationsTabAddColumnsDropdown"
>
<MSKTab
key={0}
id={Tab.MUTATIONS}
linkText={this.mutationsTabText}
>
{this.mutationsTabContent}
</MSKTab>
<MSKTab
key={1}
id={Tab.CLINICAL}
linkText={this.clinicalTabText}
>
{this.clinicalTabContent}
</MSKTab>
</MSKTabs>
</div>
</CustomDropdown>
</div>
);
}
}
9 changes: 8 additions & 1 deletion src/pages/resultsView/mutation/ResultsViewMutationMapper.tsx
Expand Up @@ -88,7 +88,8 @@ export default class ResultsViewMutationMapper extends MutationMapper<
this.props.store.mutationData,
this.props.store.indexedVariantAnnotations,
this.props.store.activeTranscript,
this.props.store.clinicalDataGroupedBySampleMap
this.props.store.clinicalDataGroupedBySampleMap,
this.props.store.mutationsTabClinicalAttributes
) === 'pending'
);
}
Expand Down Expand Up @@ -164,6 +165,12 @@ export default class ResultsViewMutationMapper extends MutationMapper<
existsSomeMutationWithAscnProperty={
this.props.existsSomeMutationWithAscnProperty
}
mutationsTabClinicalAttributes={
this.props.store.mutationsTabClinicalAttributes
}
clinicalAttributeIdToAvailableFrequency={
this.props.store.clinicalAttributeIdToAvailableFrequency
}
/>
);
}
Expand Down
Expand Up @@ -2,6 +2,7 @@ import { IHotspotIndex } from 'cbioportal-utils';
import {
Mutation,
Gene,
ClinicalAttribute,
ClinicalData,
CancerStudy,
MolecularProfile,
Expand Down Expand Up @@ -69,6 +70,10 @@ export default class ResultsViewMutationMapperStore extends MutationMapperStore
public clinicalDataGroupedBySampleMap: MobxPromise<{
[sampleId: string]: ClinicalData[];
}>,
public mutationsTabClinicalAttributes: MobxPromise<ClinicalAttribute[]>,
public clinicalAttributeIdToAvailableFrequency: MobxPromise<{
[clinicalAttributeId: string]: number;
}>,
protected genomenexusClient?: GenomeNexusAPI,
protected genomenexusInternalClient?: GenomeNexusAPIInternal,
public getTranscriptId?: () => string
Expand Down

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