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## ----loadlibs, eval=T, message = FALSE, warning = FALSE----------------------- | ||
library("nhanesA") | ||
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demoj = nhanes("DEMO_J") | ||
dim(demoj) | ||
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## merge DEMO_J and BXP_J using SEQN. | ||
bpxj = nhanes("BPX_J") | ||
data = merge(demoj, bpxj, by="SEQN") | ||
dim(data) | ||
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## ----survey, warning=FALSE, message=FALSE------------------------------------- | ||
library("survey") | ||
nhanesDesign <- svydesign(id = ~SDMVPSU, # Primary Sampling Units (PSU) | ||
strata = ~SDMVSTRA, # Stratification used in the survey | ||
weights = ~WTMEC2YR, # Survey weights | ||
nest = TRUE, # Whether PSUs are nested within strata | ||
data = data) | ||
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## ----surveydesign, message = FALSE, warning = FALSE--------------------------- | ||
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# subset survey design object | ||
dfsub = subset(nhanesDesign, data$RIDAGEYR>=40) | ||
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# subset the original dataset | ||
datasub = data[data$RIDAGEYR>=40,] | ||
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## ----ethtables, message = FALSE, warning=FALSE-------------------------------- | ||
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## mean on total data set | ||
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mean(datasub$BPXDI1, na.rm = TRUE) | ||
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##split the data by ethnicity and calculate mean of the unweighted data | ||
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unweighted_means <- sapply(split(datasub$BPXDI1, datasub$RIDRETH1), mean, na.rm=TRUE) | ||
unweighted_means | ||
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## ----svyby, message = FALSE, warning = FALSE---------------------------------- | ||
adjmns = svymean(~BPXDI1, dfsub, na.rm=TRUE) | ||
adjmns | ||
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# By ethnicity | ||
adjmnsbyEth = svyby(~BPXDI1, ~RIDRETH1, dfsub, svymean, na.rm=TRUE) | ||
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weighted_means <- as.numeric(adjmnsbyEth$BPXDI1) | ||
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combined_data <- cbind(unweighted_means, weighted_means) | ||
colnames(combined_data) <- c("Unweighted", "Weighted") | ||
combined_data | ||
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## ----message = FALSE, warning = FALSE----------------------------------------- | ||
# By Gender | ||
mns = sapply(split(datasub$BPXDI1, datasub$RIAGENDR), mean, na.rm=TRUE) | ||
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adjmnsbyGen = svyby(~BPXDI1, ~RIAGENDR, dfsub, svymean, na.rm=TRUE) | ||
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combined_data <- cbind(mns, adjmnsbyGen$BPXDI1) | ||
colnames(combined_data) <- c("Unweighted", "Weighted") | ||
combined_data | ||
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## ----message = FALSE, warning = FALSE----------------------------------------- | ||
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# For the unweighted data | ||
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quantile(datasub$BPXDI1, c(0.25,0.5,.75), na.rm = TRUE) | ||
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# For the survey weighted data | ||
svyquantile(~BPXDI1, dfsub, quantiles = c(0.25,0.5,0.75), na.rm=TRUE) | ||
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# By Gender | ||
svyby(~BPXDI1, ~RIAGENDR, dfsub, svyquantile, quantiles = c(0.5), na.rm=TRUE) | ||
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## ----message = FALSE, warning = FALSE----------------------------------------- | ||
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# For the entire dataset | ||
svyvar(~BPXDI1, dfsub, quantiles = c(0.25,0.5,0.75), na.rm=TRUE) | ||
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# By ethnicity | ||
svyby(~BPXDI1, ~RIDRETH1, dfsub, svyvar, na.rm=TRUE) | ||
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# By Gender | ||
svyby(~BPXDI1, ~RIAGENDR, dfsub, svyvar, na.rm=TRUE) | ||
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## ----message = FALSE, warning = FALSE----------------------------------------- | ||
weighted_model <- svyglm(BPXDI1 ~ RIDAGEYR + RIDRETH1, design = dfsub, family = gaussian()) | ||
summary(weighted_model) | ||
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## ----message = FALSE, warning = FALSE----------------------------------------- | ||
library(ggplot2) | ||
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## recalculating means (same as above) | ||
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unweighted_means <- sapply(split(datasub$BPXDI1, datasub$RIDRETH1), mean, na.rm=TRUE) | ||
weighted_means <- as.numeric(adjmnsbyEth$BPXDI1) | ||
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plot_data <- data.frame( | ||
Ethnicity = factor(rep(names(unweighted_means), 2), | ||
levels = names(unweighted_means)), | ||
Means = c(unweighted_means, weighted_means), | ||
Type = factor(c(rep("Unweighted", length(unweighted_means)), | ||
rep("Weighted", length(weighted_means))), | ||
levels = c("Unweighted", "Weighted")) | ||
) | ||
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# Creating the plot | ||
ggplot(plot_data, aes(x = Ethnicity, y = Means, fill = Type)) + | ||
geom_bar(stat = "identity", position = "dodge", width = 0.6) + | ||
labs(title = "Comparison of Diastolic Blood Pressure by Ethnicity", | ||
y = "Mean Diastolic Blood Pressure") + | ||
scale_fill_manual(values = c("blue", "red")) + | ||
theme_minimal() + | ||
theme(legend.title = element_blank()) | ||
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## ----message = FALSE, warning = FALSE----------------------------------------- | ||
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unweighted_model <- glm(BPXDI1 ~ RIDAGEYR + RIDRETH1, data = datasub, family = gaussian()) | ||
weighted_model <- svyglm(BPXDI1 ~ RIDAGEYR + RIDRETH1, design = dfsub, family = gaussian()) | ||
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# For the unweighted model | ||
unweighted_summary <- summary(unweighted_model) | ||
unweighted_coefs <- unweighted_summary$coefficients[, "Estimate"] | ||
unweighted_se <- unweighted_summary$coefficients[, "Std. Error"] | ||
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# For the weighted model | ||
weighted_summary <- summary(weighted_model) | ||
weighted_coefs <- as.numeric(weighted_summary$coefficients[, "Estimate"]) | ||
weighted_se <- as.numeric(weighted_summary$coefficients[, "Std. Error"]) | ||
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comparison <- data.frame( | ||
Variable = names(unweighted_coefs), | ||
Unweighted = unweighted_coefs, | ||
Weighted = as.numeric(weighted_coefs) | ||
) | ||
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print(comparison) | ||
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unweighted_df <- data.frame(Variable = names(unweighted_coefs), | ||
Estimate = unweighted_coefs, | ||
SE = unweighted_se, | ||
Type = "Unweighted") | ||
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weighted_df <- data.frame(Variable = names(unweighted_coefs), | ||
Estimate = weighted_coefs, | ||
SE = weighted_se, | ||
Type = "Weighted") | ||
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plot_data <- rbind(unweighted_df, weighted_df) | ||
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ggplot(subset(plot_data, Variable!='(Intercept)'), aes(x = Estimate, y = reorder(Variable, Estimate), color = Type)) + | ||
geom_point(position = position_dodge(0.5), size = 2.5) + | ||
geom_errorbarh(aes(xmin = Estimate - SE, xmax = Estimate + SE), | ||
height = 0.2, position = position_dodge(0.5)) + | ||
geom_vline(xintercept = 0, linetype = "dashed", color = "grey50") + | ||
labs(title = "Comparison of Regression Coefficients: Weighted vs Unweighted", | ||
x = "Coefficient Value", y = "Predictors") + | ||
theme_minimal() + | ||
scale_color_manual(values = c("Unweighted" = "blue", "Weighted" = "red")) + | ||
theme(legend.title = element_blank()) | ||
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