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hla-mm

This scripts read in output from HLAmatchmaker (Hmm) to quantify the number of mismatched epitopes in the graft-versus-host (GVH) and host-versus-graft (HVG) directions respectively. The dose of the mismatched epitopes are also taken into consideration.

Input files

  • Class1 analysis result from Hmm, tab 4 and tab 5 exported as class1rec.csv and class1don.csv respectively in the same directory as the python script.
  • Class2 analysis result from Hmm, tab 4 and tab 5 exported as class2rec.csv and class2don.csv respectively in the same directory as the python script.

Running the script

python class1gvh_hvg_v2.py
python class2gvh_hvg_v2.py

Output and further processing

"class1gvh_hvg" and "class2gvh_hvg" are generated by the scripts. The files can be imported into excel. Pivot using the "type of ep-mm".

About

Quantify epitope mismatch predicted by the HLAMatchmaker program while considering the dose and vector of the mismatch.

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