A pooled single-cell genetic screen identifies regulatory checkpoints in the continuum of the epithelial-to-mesenchymal transition

This is a resource for the article: "A pooled single-cell genetic screen identifies regulatory checkpoints in the continuum of the epithelial-to-mesenchymal transition", from the Trapnell and Shendure labs. The paper is available on the Nature Genetics website here.

Content

This repository contains all of the code associated with the manuscript as well as instructions on how to access the associated data.

Data

BAM files, matrix-marker formatted metadata matrices and monocle 2 CellDataSet objects can be downloaded from NCBI GEO Omnibus under the accession number GSE114687.

Code

The folder named code contains R files with the code used for the article.