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Designate JD.1 (XBB.1.5.102, S:L455F, S:F456L (T22928C), A14634G, T28…
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PR to correct the issue it is from #2071
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But there is still a typo, It should be XBB.1.5.102.1
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thank you i have issued a PR correcting it
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I want to highlight here that all the JD* clan has also T28282C which is directly in the Kozak Sequence of Orf9B:
![Schermata 2023-08-25 alle 22 26 38](https://private-user-images.githubusercontent.com/87669813/263384979-4a180b47-87f0-48c1-b8dd-ada8fd3c7e9c.png?jwt=eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.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.ZwfL60hGJsaGaMGEV0L2aNXmzExhZ0s7lZ988zVqaeU)
![Schermata 2023-08-25 alle 22 27 17](https://private-user-images.githubusercontent.com/87669813/263385215-b2dc30de-5c8a-4f0a-a2ca-fd6d7df61550.png?jwt=eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.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.BnoDPhmenRDsZ-Am5gY6ydGi4xvG--ptNRPmOhYEbUQ)
Kozak sequence is the OPTIMUM sequence preceding (&Following) the Start Codon enhancing (the more is similar to the Kozak sequence) or reducing (the less is similar to the ideal sequence) the initiating translation :
So the T28282C greatly improve the Kozak Sequence of Orf9b in all JD. lineages:
![Schermata 2023-08-25 alle 22 32 05](https://private-user-images.githubusercontent.com/87669813/263386951-02c9c688-1a5c-4d97-a3c9-893789fe4559.png?jwt=eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.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.R2s5GcYL2JK8BXYy-D2_q1RydoI82MfREqTJjsBYDao)
Tree from @ryhisner
Kozak : credit to @thomaspeacock and @ryhisner who opened this world to me.