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BA.5.2.21 + orf1b:1050N sublineage with S:N450D (89 Sequences) and its sublineage with S:G252S circulating in Denmark (6 sequences) #1108

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FedeGueli opened this issue Sep 24, 2022 · 2 comments
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@FedeGueli
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FedeGueli commented Sep 24, 2022

Defining mutations:
C5284T, A22910G, C25626T, C27012T + S:N450D

Tree:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_9132_f6da70.json?branchLabel=aa%20mutations&c=pango_lineage_usher&label=nuc%20mutations:C25626T
Schermata 2022-09-24 alle 22 57 11

First sequence: EPI_ISL_14541309|2022-08-04 from Japan
Nr of sequences: 18
EPI_ISL_14718521
EPI_ISL_15044951
EPI_ISL_14774478
EPI_ISL_14541309
EPI_ISL_15061381
EPI_ISL_15037606
EPI_ISL_14717216
EPI_ISL_15037081
EPI_ISL_14950369
EPI_ISL_15015737
EPI_ISL_14808315
EPI_ISL_14995495
EPI_ISL_14822622

Countries:
GeographicDistribution

Covspectrum query: C5284T, A22910G, C25626T, C27012T + S:N450D

https://cov-spectrum.org/explore/World/AllSamples/Past6M/variants?aaMutations=S%3AN450D&nucMutations=C5284T%2CA22910G%2CC25626T%2CC27012T&

EDITED

Digging a bit in this lineage i found 5 very recent uploads from Denmark belonging to this lineage which have acquired another NTD mutation S:G252S and Orf3a:A110S and nuc: T15930C
Schermata 2022-09-24 alle 23 27 59
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_13494_f73390.json?branchLabel=aa%20mutations&c=pango_lineage_usher&label=nuc%20mutations:C25626T

To track this last one the Gisaid query is : NSP13_T127N,Spike_G252S,Spike_N450D

Covspectrum for this last danish sublineage: https://cov-spectrum.org/explore/World/AllSamples/Past2M/variants?aaMutations=S%3AG252S%2COrf3a%3AA110S&nucMutations=T15930C&

@FedeGueli FedeGueli changed the title BA.5.2 +orf1b:1050N sublineage with S:N450D (18 Sequences) BA.5.2 +orf1b:1050N sublineage with S:N450D (18 Sequences) and its sublineage with S:G252S circualting in Denamrk (5 sequences) Sep 24, 2022
@FedeGueli FedeGueli changed the title BA.5.2 +orf1b:1050N sublineage with S:N450D (18 Sequences) and its sublineage with S:G252S circualting in Denamrk (5 sequences) BA.5.2 +orf1b:1050N sublineage with S:N450D (23 Sequences) and its sublineage with S:G252S circulating in Denmark (5 sequences) Sep 24, 2022
@FedeGueli FedeGueli changed the title BA.5.2 +orf1b:1050N sublineage with S:N450D (23 Sequences) and its sublineage with S:G252S circulating in Denmark (5 sequences) BA.5.2 +orf1b:1050N sublineage with S:N450D (30 Sequences) and its sublineage with S:G252S circulating in Denmark (5 sequences) Oct 1, 2022
@FedeGueli
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30 sequences as today of this lineage on CovSpectrum

@FedeGueli FedeGueli changed the title BA.5.2 +orf1b:1050N sublineage with S:N450D (30 Sequences) and its sublineage with S:G252S circulating in Denmark (5 sequences) BA.5.2.21 + orf1b:1050N sublineage with S:N450D (30 Sequences) and its sublineage with S:G252S circulating in Denmark (5 sequences) Oct 1, 2022
@FedeGueli FedeGueli changed the title BA.5.2.21 + orf1b:1050N sublineage with S:N450D (30 Sequences) and its sublineage with S:G252S circulating in Denmark (5 sequences) BA.5.2.21 + orf1b:1050N sublineage with S:N450D (51 Sequences) and its sublineage with S:G252S circulating in Denmark (6 sequences) Oct 11, 2022
@FedeGueli
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FedeGueli commented Oct 11, 2022

@FedeGueli FedeGueli changed the title BA.5.2.21 + orf1b:1050N sublineage with S:N450D (51 Sequences) and its sublineage with S:G252S circulating in Denmark (6 sequences) BA.5.2.21 + orf1b:1050N sublineage with S:N450D (89 Sequences) and its sublineage with S:G252S circulating in Denmark (6 sequences) Oct 11, 2022
@corneliusroemer corneliusroemer added this to the CN.1 milestone Oct 11, 2022
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