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Proposal for a sublineage of BM.1.1 (BA.2.75.3 with S:R346T and S:F486S)
Earliest seq: 2022-10-11 (India)
Countries detected: Thailand (4 seq), Belgium, Indonesia, Turkey (3 each), Israel, Singapore, USA (2 each), Canada, Denmark, Germany, India, Ireland, South Korea (1 each)
Mutations on top of BM.1.1:
S: K356T, T572I
ORF1a: S216Y, D629A
nuc: C3130T (shared with BM.1.1.3), G29527A
GISAID query: nucleotide mutations C912A, A2151C
This lineage has a lot of diversity and has turned up all over the world but there doesn't seem to be much of it in any particular place, suggesting it might be more prevalent in some undersampled area. The S:346T/356T combination is convergent with BN.1, and interestingly there are several BN.1* branches with S:T572I; it may provide a small advantage though the evidence is unclear right now.
Proposal for a sublineage of BM.1.1 (BA.2.75.3 with S:R346T and S:F486S)
Earliest seq: 2022-10-11 (India)
Countries detected: Thailand (4 seq), Belgium, Indonesia, Turkey (3 each), Israel, Singapore, USA (2 each), Canada, Denmark, Germany, India, Ireland, South Korea (1 each)
Mutations on top of BM.1.1:
S: K356T, T572I
ORF1a: S216Y, D629A
nuc: C3130T (shared with BM.1.1.3), G29527A
GISAID query: nucleotide mutations C912A, A2151C
This lineage has a lot of diversity and has turned up all over the world but there doesn't seem to be much of it in any particular place, suggesting it might be more prevalent in some undersampled area. The S:346T/356T combination is convergent with BN.1, and interestingly there are several BN.1* branches with S:T572I; it may provide a small advantage though the evidence is unclear right now.
https://nextstrain.org/fetch/github.com/silcn/subtreeAuspice1/raw/main/auspice/subtreeAuspice1_genome_2f22e_bbd1d0.json?branchLabel=Spike%20mutations&c=country&label=id:node_7730754
https://cov-spectrum.org/explore/World/AllSamples/Past6M/variants?variantQuery=nextcladePangoLineage%3ABA.2.75*+%26+%5B3-of%3A+C912A%2C+A2151C%2C+A22629C%2C+C23277T%2C+G29527A%5D&
EPI_ISLs
EPI_ISL_15398204
EPI_ISL_15486658
EPI_ISL_15710478
EPI_ISL_15724709
EPI_ISL_15733682
EPI_ISL_15778331
EPI_ISL_15781195
EPI_ISL_15904364
EPI_ISL_15927311
EPI_ISL_15928010
EPI_ISL_15928038
EPI_ISL_15973729
EPI_ISL_15999437
EPI_ISL_16074752
EPI_ISL_16087412
EPI_ISL_16093058
EPI_ISL_16093059
EPI_ISL_16097652
EPI_ISL_16109862
EPI_ISL_16111879
EPI_ISL_16111880
EPI_ISL_16121725
EPI_ISL_16121726
EPI_ISL_16122105
EPI_ISL_16129916
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