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pfrommolt authored and gaborcsardi committed Feb 15, 2010
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15 changes: 10 additions & 5 deletions DESCRIPTION
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Package: bifactorial
Version: 1.4.1
Date: 2008-09-29
Version: 1.4.2
Date: 2010-02-15
Author: Peter Frommolt
Maintainer: Peter Frommolt <peter.frommolt@uni-koeln.de>
Title: Inferences for bi- and trifactorial trial designs
Depends: mvtnorm,multcomp,lattice,graphics,methods
Description: This package makes global and multiple inferences for given bi- and trifactorial clinical trial designs using bootstrap methods and a classical approach.
Depends: mvtnorm,multcomp,lattice,graphics,methods,Rcpp (>= 0.7.4)
Description: This package makes global and multiple inferences for
given bi- and trifactorial clinical trial designs using
bootstrap methods and a classical approach.
URL: http://portal.ccg.uni-koeln.de
License: GPL
Packaged: Mon Sep 29 09:32:49 2008; pf
Packaged: 2010-02-16 08:27:02 UTC; frommolt
Repository: CRAN
Date/Publication: 2010-02-16 09:36:45
7 changes: 5 additions & 2 deletions man/avemax.Rd
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Expand Up @@ -69,6 +69,9 @@ maxtest(C,test=NULL,method="bootstrap",nboot=NULL,simerror=NULL,...)
\item{call}{The function call.}
}
\references{
Frommolt P, Hellmich M (2009): Resampling in multiple-dose factorial
designs. Biometrical J 51(6), pp. 915-31
Hellmich M, Lehmacher W (2005): Closure procedures for monotone
bi-factorial dose-response designs. Biometrics 61, pp. 269-276
Expand All @@ -79,12 +82,12 @@ maxtest(C,test=NULL,method="bootstrap",nboot=NULL,simerror=NULL,...)
fixed-dose combination drug studies. Biometrics 53, pp. 498-503
Hung HMJ (2000): Evaluation of a combination drug with multiple doses
in unbalanced factorial design clinical trials. Statistics in Medicine
in unbalanced factorial design clinical trials. Statist Med
19, pp. 2079-2087
}
\author{
Peter Frommolt, University of Cologne \email{peter.frommolt@uni-koeln.de}\cr
\url{http://www.medizin.uni-koeln.de/kai/imsie/peter.frommolt/}
\url{http://portal.ccg.uni-koeln.de}
}
\note{
The performance of the bootstrap-based approach and the method from Hung
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11 changes: 7 additions & 4 deletions man/bifactorial.Rd
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Expand Up @@ -49,11 +49,14 @@
available by the generic functions \code{avetest} and \code{maxtest}.
}
\author{Peter Frommolt, University of Cologne \email{peter.frommolt@uni-koeln.de}\cr
\url{http://www.medizin.uni-koeln.de/kai/imsie/homepages/peter.frommolt/}
\url{http://portal.ccg.uni-koeln.de}
}
\references{
Bretz F, Genz A, Hothorn LA (2001): On the numerical availability of
multiple comparison procedures. Biometrical Journal 43/5, pp. 645-656
multiple comparison procedures. Biometrical J 43/5, pp. 645-656

Frommolt P, Hellmich M (2009): Resampling in multiple-dose factorial
designs. Biometrical J 51(6), pp. 915-31

Hellmich M, Lehmacher W (2005): Closure procedures for monotone bi-factorial
dose-response designs. Biometrics 61, pp. 269-276
Expand All @@ -65,14 +68,14 @@
fixed-dose combination drug studies. Biometrics 53, pp. 498-503

Hung HMJ (2000): Evaluation of a combination drug with multiple doses in
unbalanced factorial design clinical trials. Statistics in Medicine
unbalanced factorial design clinical trials. Statist Med
19, pp. 2079-2087

Laska EM, Meisner MJ (1989): Testing whether an identified treatment is
best. Biometrics 45, pp. 1139-1151

Snapinn SM (1987): Evaluating the efficacy of a combination
therapy. Statistics in Medicine 6, pp. 657-665
therapy. Statist Med 6, pp. 657-665

Westfall PH, Young SS (1993): Resampling-based multiple testing. John
Wiley & Sons, Inc., New York
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5 changes: 4 additions & 1 deletion man/carpetcube.Rd
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Expand Up @@ -55,6 +55,9 @@ cube(data,D,...)
\item{n}{Numeric vector of sample sizes in the respective groups.}
}
\references{
Frommolt P, Hellmich M (2009): Resampling in multiple-dose factorial
designs. Biometrical J, 51(6), pp. 915-31

Hung HMJ, Chi GYH, Lipicky RJ (1993): Testing for the existence of a
desirable dose combination. Biometrics 49, pp. 85-94

Expand All @@ -63,7 +66,7 @@ cube(data,D,...)
Medicine 19, pp. 2079-2087
}
\author{Peter Frommolt, University of Cologne \email{peter.frommolt@uni-koeln.de}\cr
\url{http://www.medizin.uni-koeln.de/kai/imsie/homepages/peter.frommolt/}
\url{http://portal.ccg.uni-koeln.de}
}
\seealso{\code{\link{bifactorial}}, \code{\link{mintest}},
\code{\link{margint}}, \code{\link{avetest}}, \code{\link{maxtest}}}
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10 changes: 6 additions & 4 deletions man/multinf.Rd
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Expand Up @@ -108,15 +108,17 @@ margint(C,test=NULL,method="bootstrap",nboot=NULL,simerror=NULL,
\item{call}{Function call.}
}
\references{
Frommolt P, Hellmich M (2009): Resampling in multiple-dose factorial
designs. Biometrical J 51(6), pp. 915-31
Hung HMJ, Chi GYH, Lipicky RJ (1993): Testing for the existence of a
desirable dose combination. Biometrics 49, pp. 85-94
Hung HMJ, Wang SJ (1997): Large-sample tests for binary outcomes in
fixed-dose combination drug studies. Biometrics 53, pp. 498-503
Hung HMJ (2000): Evaluation of a combination drug with multiple doses in
unbalanced factorial design clinical trials. Statistics in Medicine
19, pp. 2079-2087
unbalanced factorial design clinical trials. Statist Med 19, pp. 2079-2087
Hellmich M, Lehmacher W (2005): Closure procedures for monotone bi-factorial
dose-response designs. Biometrics 61, pp. 269-276
Expand All @@ -125,13 +127,13 @@ margint(C,test=NULL,method="bootstrap",nboot=NULL,simerror=NULL,
best. Biometrics 45, pp. 1139-1151
Snapinn SM (1987): Evaluating the efficacy of a combination
therapy. Statistics in Medicine 6, pp. 657-665
therapy. Statist Med 6, pp. 657-665
Westfall PH, Young SS (1993): Resampling-based multiple testing. John
Wiley & Sons, Inc., New York
}
\author{Peter Frommolt, University of Cologne \email{peter.frommolt@uni-koeln.de}\cr
\url{http://www.medizin.uni-koeln.de/kai/imsie/homepages/peter.frommolt/}
\url{http://portal.ccg.uni-koeln.de}
}
\note{
Performance of the implemented methods has been evaluated and compared. The min-test performs very
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2 changes: 2 additions & 0 deletions src/Makevars
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PKG_CPPFLAGS = -I. `${R_HOME}/bin/Rscript -e "Rcpp:::CxxFlags()"`
PKG_LIBS = `${R_HOME}/bin/Rscript -e "Rcpp:::LdFlags()"`
2 changes: 2 additions & 0 deletions src/Makevars.win
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PKG_LIBS = `Rscript -e 'Rcpp:::LdFlags()'`
PKG_CXXFLAGS = `Rscript -e 'Rcpp:::CxxFlags()'` -I.

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