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20 changes: 8 additions & 12 deletions DESCRIPTION
@@ -1,21 +1,17 @@
Package: hisemi
Type: Package
Title: Hierarchical Semiparametric Regression of Test Statistics
Version: 1.0-249
Date: 2012-08-01
Author: Long Qu
Maintainer: Long Qu <longorognol@hotmail.com>
Version: 1.0-319
Date: 2013-08-30
Author: Long Qu
Maintainer: Long Qu <long.qu@wright.edu>
Depends: R (>= 2.12)
Imports: Matrix , Iso(>= 0.0-5), splines, fda
Suggests: multtest, qvalue, pi0
Enhances: stats, graphics
Description: This package implements methods for hierarchical
semiparametric regression models for test statistics.
Specifically, test statistics given the null/alternative
hypotheses are modeled parametrically, whereas the unobservable
status of null/alternative hypotheses are modeled using
nonparametric additive logistic regression over covariates.
Description: This package implements methods for hierarchical semiparametric regression models for test statistics. Specifically, test statistics given the null/alternative hypotheses are modeled parametrically, whereas the unobservable status of null/alternative hypotheses are modeled using nonparametric additive logistic regression over covariates.
License: GPL (>= 2)
Packaged: 2012-08-01 13:28:41 UTC; longor
Packaged: 2013-08-30 21:06:27 UTC; Longor
NeedsCompilation: no
Repository: CRAN
Date/Publication: 2012-08-01 14:05:30
Date/Publication: 2013-08-31 14:46:21
44 changes: 22 additions & 22 deletions MD5
@@ -1,4 +1,4 @@
55e2e919599cabbfc48aba6dd10152a8 *DESCRIPTION
1ee79f55b395375add1f5d3cec6d5267 *DESCRIPTION
b1187d229f05a1255b55f097935a4315 *NAMESPACE
665f70dec799416ce05115f62419ca65 *R/EM.Newton.R
2c5f3b7504cec7c334c55b761b28ab9c *R/EM.Newton.support.R
Expand All @@ -10,25 +10,25 @@ d4594409d99096ca9efe3cdc67be6ea5 *R/directSum.R
c4fe3af705aeade917a450c731f61c58 *R/n.knots.R
de4722ae0f0f58b1ec9aef9b22aa92a1 *R/scaledTMix.R
e3d96549dcf56c1089776081515235ed *R/tPoly.newton.R
ac6b0ab98c8cce0798196358f0d9b40c *man/EMupdate.Rd
ecc5d0b047c1f75526507f18b825bd9f *man/NRupdate.Rd
2e86f51a586e45d10d9a5032425f71de *man/OsplinePen.Rd
d74465ddfc90a3c940be105a55581fba *man/coef.hisemit.Rd
e685e09423b156d63d38d9efcc118b0b *man/confint.hisemit.Rd
d07e2027775c34281faa633f19dd846b *man/directSum.Rd
477c35a63fe3f47e44c6b6e1fb6a6d45 *man/fitted.hisemit.Rd
8bfc412d5450bb12b56d410ec60a40b5 *man/EMupdate.Rd
98f28ee3fbe20e5481766f24279acd00 *man/NRupdate.Rd
fab4c1f06335cb846db213f95b210f4f *man/OsplinePen.Rd
32927eeaf0ef42368036057f1bce4ca6 *man/coef.hisemit.Rd
0d3e033c4a3bce199562384ca931d6cb *man/confint.hisemit.Rd
333a02371ca3b1bd2ed126078df155c1 *man/directSum.Rd
192da12444fa0125a2389e170a8570ab *man/fitted.hisemit.Rd
8196fb9769464b86522e2207a4f80b48 *man/hisemi-internal.Rd
a46aee1b53dfc285fe104efbf3be608f *man/hisemi-package.Rd
bf24b35305affa8d77756d29151251f0 *man/logLik.hisemit.Rd
97ee43763742b9d9c5bdc398c79b1542 *man/logistic.enp.Rd
2373db5649de8683a33a86d70eb66d75 *man/logit.Rd
cd15b16576e66ad2f6896ea37f680c8a *man/n.knots.Rd
36955a210f8db84276b3dd68348b813b *man/penLik.EMNewton.Rd
ca35d94477cf06aa1941191ae81dce86 *man/plot.hisemit.Rd
0b8dbe7d55c851ac767c7d368bc91271 *man/print.hisemit.Rd
21f0fe0d1a2b889eaede82de91091e11 *man/resid.hisemit.Rd
5584d019d6f73808e5492f33baee59e3 *man/scaledTMix.null.Rd
ddec67a0c247496873beefd09089520d *man/scaledTMix.psat.Rd
9a63425c2b3819cb10389a2dd26e687d *man/scaledTMix.sat.Rd
28973bb3209d55047cd2df4b5a42b247 *man/tPoly.newton.Rd
2e85b3a3839512e48df27c8f5b274785 *man/vcov.hisemit.Rd
24b2ae60e168cca48b1d13ede234068f *man/hisemi-package.Rd
bb1962251de1f02c5ffeb687dee9481e *man/logLik.hisemit.Rd
1564eae6216725cce3b887b1aa993ec9 *man/logistic.enp.Rd
aabd0dd8bc96edb8801ae14dbdd47ba5 *man/logit.Rd
3e5fcc695b1e69ee7ef7c8a4f2558e41 *man/n.knots.Rd
0505d27a05f2a557b58b557a2ca61365 *man/penLik.EMNewton.Rd
1f90bdaf8296e2c46165929a3f79beba *man/plot.hisemit.Rd
89cb83934afc83a70e1e1529fdefc839 *man/print.hisemit.Rd
c29314fd1a9ab303e370b037aba90d1e *man/resid.hisemit.Rd
a2243802abe16e3ce7d08f24b024ddd2 *man/scaledTMix.null.Rd
bad5c34a0f9b7bdd945a7e04da90470c *man/scaledTMix.psat.Rd
c95205ea391d7292676e1e8e02eb4487 *man/scaledTMix.sat.Rd
565fd88a4646ce7874d5569c7feb3b13 *man/tPoly.newton.Rd
d65cbdd80f8fc794dc4d12c52cc564c5 *man/vcov.hisemit.Rd
4 changes: 2 additions & 2 deletions man/EMupdate.Rd
Expand Up @@ -33,8 +33,8 @@ EMupdate(starts, nLogLik.pen, optim.method, H, tstat, df, dt0,
\value{
A numeric vector of updated parameter estimates. The scale factor is in the \code{log(scale.fact-1)} parameterization.
}
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics (to appear)}
\author{ Long Qu \email{longorognol@hotmail.com} }
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics, 68(4):1168-1177}
\author{ Long Qu \email{long.qu@wright.edu} }
%\note{
%}
\seealso{ \code{\link{penLik.EMNewton}}, \code{\link{NRupdate}} }
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4 changes: 2 additions & 2 deletions man/NRupdate.Rd
Expand Up @@ -35,8 +35,8 @@ NRupdate(f, starts, gradient, hessian, ..., ridge0 = 1e-06,
\item{\code{'iter'}}{ The number of iterations}
\item{\code{'hessian'}}{ The final Hessian matrix, only available if \code{return.hessian=TRUE}. }
}
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics (to appear)}
\author{ Long Qu \email{longorognol@hotmail.com} }
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics, 68(4):1168-1177}
\author{ Long Qu \email{long.qu@wright.edu} }
%\note{
%}
\seealso{ \code{\link{penLik.EMNewton}}, \code{\link{EMupdate}} }
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2 changes: 1 addition & 1 deletion man/OsplinePen.Rd
Expand Up @@ -24,7 +24,7 @@ OsplinePen(Boundary.knots, knots, ord=1)
\references{
Wand, M. P. and Ormerod, J. T. (2008) On semiparametric regression with O'Sullivan penalized splines. Aust. N. Z. J. Stat. 50(2), 179--198.
}
\author{ Long Qu [\email{longorognol@hotmail.com}] }
\author{ Long Qu [\email{long.qu@wright.edu}] }
\note{
When knots are selected by all distinct x values, this returns the penalty matrix of smoothing splines.
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4 changes: 2 additions & 2 deletions man/coef.hisemit.Rd
Expand Up @@ -26,8 +26,8 @@
\value{
A numeric vector of estimated parameters
}
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics (to appear) }
\author{ Long Qu \email{longorognol@hotmail.com} }
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics, 68(4):1168-1177 }
\author{ Long Qu \email{long.qu@wright.edu} }
%\note{
%}
\seealso{ \code{\link{plot.hisemit}}, \code{\link{fitted.hisemit}}, \code{\link{coef.hisemit}}, \code{\link{vcov.hisemit}}, \code{\link{residuals.hisemit}}, \code{\link{logLik.hisemit}}, \code{\link{confint.hisemit}}, \code{\link{print.hisemit}},
Expand Down
4 changes: 2 additions & 2 deletions man/confint.hisemit.Rd
Expand Up @@ -38,8 +38,8 @@ Extract Wald-type asymptotic confidence intervals from a \code{hisemit} object.
\value{
A matrix (or vector) with columns giving lower and upper confidence limits for each parameter.
}
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics (to appear)}
\author{ Long Qu \email{longorognol@hotmail.com} }
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics, 68(4):1168-1177}
\author{ Long Qu \email{long.qu@wright.edu} }
%\note{
%}
\seealso{ \code{\link{plot.hisemit}}, \code{\link{fitted.hisemit}}, \code{\link{coef.hisemit}}, \code{\link{vcov.hisemit}}, \code{\link{residuals.hisemit}}, \code{\link{logLik.hisemit}}, \code{\link{confint.hisemit}}, \code{\link{print.hisemit}},
Expand Down
2 changes: 1 addition & 1 deletion man/directSum.Rd
Expand Up @@ -21,7 +21,7 @@ The function treats each matrix as an element and put the element along the diag
}
%\references{
%}
\author{ Long Qu \email{longorognol@hotmail.com}
\author{ Long Qu \email{long.qu@wright.edu}
}
%\note{
%}
Expand Down
4 changes: 2 additions & 2 deletions man/fitted.hisemit.Rd
Expand Up @@ -35,8 +35,8 @@
\value{
A numeric vector
}
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics (to appear)}
\author{ Long Qu \email{longorognol@hotmail.com} }
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics, 68(4):1168-1177}
\author{ Long Qu \email{long.qu@wright.edu} }
%\note{
%}
\seealso{ \code{\link{plot.hisemit}}, \code{\link{fitted.hisemit}}, \code{\link{coef.hisemit}}, \code{\link{vcov.hisemit}}, \code{\link{residuals.hisemit}}, \code{\link{logLik.hisemit}}, \code{\link{confint.hisemit}}, \code{\link{print.hisemit}},
Expand Down
10 changes: 5 additions & 5 deletions man/hisemi-package.Rd
Expand Up @@ -12,8 +12,8 @@ The package includes functions for fitting hierarchical semiparametric regressio
\tabular{ll}{
Package: \tab hisemi\cr
Type: \tab Package\cr
Version: \tab 1.0-249\cr
Date: \tab 2012-08-01\cr
Version: \tab 1.0-319\cr
Date: \tab 2013-08-30\cr
License: \tab GPL version 2 or newer\cr
LazyLoad: \tab yes\cr
}
Expand All @@ -37,11 +37,11 @@ LazyLoad: \tab yes\cr
}
}
\author{
Long Qu \email{longorognol@hotmail.com}
Long Qu \email{long.qu@wright.edu}

Maintainer: Long Qu \email{longorognol@hotmail.com}
Maintainer: Long Qu \email{long.qu@wright.edu}
}
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012). A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics (to appear)}
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012). A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics, 68(4):1168-1177}
\keyword{ package }
\keyword{ models }
\keyword{ regression }
Expand Down
4 changes: 2 additions & 2 deletions man/logLik.hisemit.Rd
Expand Up @@ -19,8 +19,8 @@
\value{
An object of class \code{'logLik'}.
}
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics (to appear)}
\author{ Long Qu \email{longorognol@hotmail.com} }
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics, 68(4):1168-1177}
\author{ Long Qu \email{long.qu@wright.edu} }
%\note{
%}
\seealso{ \code{\link{plot.hisemit}}, \code{\link{fitted.hisemit}}, \code{\link{coef.hisemit}}, \code{\link{vcov.hisemit}}, \code{\link{residuals.hisemit}}, \code{\link{logLik.hisemit}}, \code{\link{confint.hisemit}}, \code{\link{print.hisemit}},
Expand Down
2 changes: 1 addition & 1 deletion man/logistic.enp.Rd
Expand Up @@ -30,7 +30,7 @@ A numeric vector of fitted effective number of parameters, with attributes
\item{mode}{ The model of enps from a isotonic fit}
}
%\references{ }
\author{ Long Qu \email{longorognol@hotmail.com} }
\author{ Long Qu \email{long.qu@wright.edu} }
%\note{
%}
\seealso{ \code{\link{nls}} }
Expand Down
2 changes: 1 addition & 1 deletion man/logit.Rd
Expand Up @@ -23,7 +23,7 @@ logit.inv(eta)
A link function or its inverse. See \code{\link{make.link}}.
}
%\references{ }
\author{ Long Qu \email{longorognol@hotmail.com}}
\author{ Long Qu \email{long.qu@wright.edu}}
%\note{
%}
\seealso{\code{\link{make.link}}}
Expand Down
4 changes: 2 additions & 2 deletions man/n.knots.Rd
Expand Up @@ -25,10 +25,10 @@ Li, Y. and Ruppert, D. (2008). on the asymptotics of penalized splines. Biometri

Ruppert, D. (2002). Selecting the number of knots for penalized splines. Journal of Computational and Graphical Statistics 11, 735--757.

Qu, L., Nettleton, D., and Dekkers J. C. M. (2012) A hierarchical semiparametric model for incorporating inter-gene information for analysis of genomic data. Biometrics (to appear).
Qu, L., Nettleton, D., and Dekkers J. C. M. (2012) A hierarchical semiparametric model for incorporating inter-gene information for analysis of genomic data. Biometrics, 68(4):1168-1177.

}
\author{ Long Qu \email{longorognol@hotmail.com}
\author{ Long Qu \email{long.qu@wright.edu}
}
%\note{
%}
Expand Down
4 changes: 2 additions & 2 deletions man/penLik.EMNewton.Rd
Expand Up @@ -83,8 +83,8 @@ penLik.EMNewton(tstat, x, df, spar = c(10^seq(-1,8,length=30), Inf),
\note{
When spar is too small, the results need to be treated cautiously. It is advisable to plot the results as a check.
}
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics (to appear)}
\author{ Long Qu \email{longorognol@hotmail.com} }
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics, 68(4):1168-1177}
\author{ Long Qu \email{long.qu@wright.edu} }
%\note{
%}
\seealso{ \code{\link{plot.hisemit}}, \code{\link{fitted.hisemit}}, \code{\link{coef.hisemit}},
Expand Down
4 changes: 2 additions & 2 deletions man/plot.hisemit.Rd
Expand Up @@ -36,8 +36,8 @@ For histograms of residuals, an object from \code{\link{hist}} is returned.
For scatter plot of residuals, an object from \code{\link{plot}} is returned.
For tuning plot, a matrix with the range of tuning criterion is returned.
}
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics (to appear)}
\author{ Long Qu \email{longorognol@hotmail.com} }
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics, 68(4):1168-1177}
\author{ Long Qu \email{long.qu@wright.edu} }
%\note{
%}
\seealso{ \code{\link{plot.hisemit}}, \code{\link{fitted.hisemit}}, \code{\link{coef.hisemit}}, \code{\link{vcov.hisemit}}, \code{\link{residuals.hisemit}}, \code{\link{logLik.hisemit}}, \code{\link{confint.hisemit}}, \code{\link{print.hisemit}},
Expand Down
4 changes: 2 additions & 2 deletions man/print.hisemit.Rd
Expand Up @@ -21,8 +21,8 @@
\value{
The same as the results from the corresponding method for the \code{list} object.
}
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics (to appear)}
\author{ Long Qu \email{longorognol@hotmail.com} }
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics, 68(4):1168-1177}
\author{ Long Qu \email{long.qu@wright.edu} }
%\note{
%}
\seealso{ \code{\link{plot.hisemit}}, \code{\link{fitted.hisemit}}, \code{\link{coef.hisemit}}, \code{\link{vcov.hisemit}}, \code{\link{residuals.hisemit}}, \code{\link{logLik.hisemit}}, \code{\link{confint.hisemit}}, \code{\link{print.hisemit}},
Expand Down
4 changes: 2 additions & 2 deletions man/resid.hisemit.Rd
Expand Up @@ -23,9 +23,9 @@
A numeric vector residuals.
}
\references{
Qu, Nettleton, Dekkers (2012) A Hierarchical Semiparametric Model for Incorporating Inter-gene Information for Analysis of Genomic Data. Biometrics (to appear)
Qu, Nettleton, Dekkers (2012) A Hierarchical Semiparametric Model for Incorporating Inter-gene Information for Analysis of Genomic Data. Biometrics, 68(4):1168-1177
}
\author{ Long Qu \email{longorognol@hotmail.com} }
\author{ Long Qu \email{long.qu@wright.edu} }
%\note{
%}
\seealso{ \code{\link{plot.hisemit}}, \code{\link{fitted.hisemit}}, \code{\link{coef.hisemit}}, \code{\link{vcov.hisemit}}, \code{\link{residuals.hisemit}}, \code{\link{logLik.hisemit}}, \code{\link{confint.hisemit}}, \code{\link{print.hisemit}},
Expand Down
4 changes: 2 additions & 2 deletions man/scaledTMix.null.Rd
Expand Up @@ -25,9 +25,9 @@ scaledTMix.null(tstat, df, starts =
A \code{hesimit} object.
}
\references{
Qu, Nettleton, Dekkers (2012) A Hierarchical Semiparametric Model for Incorporating Inter-gene Information for Analysis of Genomic Data. Biometrics (to appear)
Qu, Nettleton, Dekkers (2012) A Hierarchical Semiparametric Model for Incorporating Inter-gene Information for Analysis of Genomic Data. Biometrics, 68(4):1168-1177
}
\author{ Long Qu \email{longorognol@hotmail.com}
\author{ Long Qu \email{long.qu@wright.edu}
}
%\note{
% ~~further notes~~
Expand Down
2 changes: 1 addition & 1 deletion man/scaledTMix.psat.Rd
Expand Up @@ -28,7 +28,7 @@ scaledTMix.psat(tstat, df, upper0 = 2)
\item{pi0}{ A numeric vector of 0 or 1, which are the maximum likelihood estimate of \code{pi0}}
}
%\references{ }
\author{ Long Qu \email{longorognol@hotmail.com}
\author{ Long Qu \email{long.qu@wright.edu}
}
%\note{}
\seealso{ \code{\link{scaledTMix.null}}, \code{\link{scaledTMix.sat}}}
Expand Down
2 changes: 1 addition & 1 deletion man/scaledTMix.sat.Rd
Expand Up @@ -22,7 +22,7 @@ scaledTMix.sat(tstat, df)
\item{logLik }{ A numeric vector of log likelihood}
}
%\references{ }
\author{ Long Qu \email{longorognol@hotmail.com}
\author{ Long Qu \email{long.qu@wright.edu}
}
\note{
Whenever the absolute value of the \code{tstat} is less than 1, \code{pi0} will be esitmated to be 1 and the scale will also be 1. Otherwise, the \code{pi0} will be estimated to be 0 and scale will be the absolute value of \code{tstat}.
Expand Down
4 changes: 2 additions & 2 deletions man/tPoly.newton.Rd
Expand Up @@ -80,8 +80,8 @@ tPoly.newton(tstat, x, df, starts,
\item{penalty:}{ Penalty term}
\item{saturated.ll:}{ Saturated log likelihood}}}
}
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics (to appear)}
\author{ Long Qu \email{longorognol@hotmail.com} }
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics, 68(4):1168-1177}
\author{ Long Qu \email{long.qu@wright.edu} }
%\note{
%}
\seealso{ \code{\link{penLik.EMNewton}}, \code{\link{plot.hisemit}}, \code{\link{fitted.hisemit}}, \code{\link{coef.hisemit}},
Expand Down
4 changes: 2 additions & 2 deletions man/vcov.hisemit.Rd
Expand Up @@ -19,8 +19,8 @@
\value{
A numerical matrix.
}
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics (to appear)}
\author{ Long Qu \email{longorognol@hotmail.com} }
\references{ Long Qu, Dan Nettleton, Jack Dekkers (2012) A hierarchical semiparametric model for incorporating inter-gene relationship information for analysis of genomic data. Biometrics, 68(4):1168-1177}
\author{ Long Qu \email{long.qu@wright.edu} }
%\note{
%}
\seealso{ \code{\link{plot.hisemit}}, \code{\link{fitted.hisemit}}, \code{\link{coef.hisemit}}, \code{\link{vcov.hisemit}}, \code{\link{residuals.hisemit}}, \code{\link{logLik.hisemit}}, \code{\link{confint.hisemit}}, \code{\link{print.hisemit}},
Expand Down

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