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data analysis & event prediction in diabetes
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README.md

interest areas

people

  • Dr Chris Sainsbury Consultant Diabetes & Endocrinology. @csainsbury. x@y where x=c.sainsbury & y=nhs.net
  • Dr Greg Jones Consultant Diabetes & Endocrinology. Honorary Associate Professor, @gregcjones. x@y where x=g.jones3 & y=nhs.net
  • Dr Debbie Morrison GPSI Diabetes. Honorary Clinical Lecturer
  • Dr Sean Harbison Clinical Development Fellow

output

2019 Thyroid replacement therapy, thyroid stimulating hormone concentrations, and long term health outcomes in patients with hypothyroidism: longitudinal study. R Thayakaran, NJ Adderley, C Sainsbury, B Torlinska, K Boelaert, D Šumilo, M Price, GN Thomas, KA Toulis, K Nirantharakumar. BMJ 2019; 366 | https://doi.org/10.1136/bmj.l4892 | web

2018 Admission Glucose Number (AGN): A point of admission score associated with inpatient glucose variability, hypoglycaemia and mortality. J McKechnie, R Maitland, CAR Sainsbury, GC Jones. Journal of Diabetes Science and Technology | https://doi.org/10.1177/1932296818800722 | web

2018 Identifying modifiable risk factors to reduce inpatient hypoglycaemia. PD Murray, BA McKee, CAR Sainsbury, GC Jones. Clinical Pharmacist, August 2018, Vol 10, No 8, online | DOI: 10.1211/CP.2018.20205227 | web

2018 Structured education using Dose Adjustment for Normal Eating (DAFNE) reduces long term HbA1c and HbA1c variability. GS Walker, JY Chen, H Hopkinson, CAR Sainsbury, GC Jones. 2018. Diabetic Medicine | web

2018 Visit-to-visit HbA1c variability and systolic blood pressure (SBP) variability are significantly and additively associated with mortality in people with type 1 diabetes: an observational study. Stuart S. Wightman, Christopher A.R. Sainsbury, Gregory C. Jones. Diabetes Obesity & Metabolism | web

2017 HbA1c variability is associated with increased mortality and earlier hospital admission in people with type 1 diabetes. Graham S Walker, Scott G Cunningham, Christopher A.R. Sainsbury, Gregory C. Jones. Diabetic Medicine | web

2017 A practical review of C-Peptide Testing in Diabetes. E Leighton, C Sainsbury, G Jones. Diabetes Ther | web | .pdf

2017 Hypoglycemia and Clinical Outcomes in Hospitalized Patients With Diabetes: Does Association With Adverse Outcomes Remain When Number of Glucose Tests Performed Is Accounted For? GC Jones, JG Timmons, SG Cunningham, SJ Cleland, CAR Sainsbury Journal of Diabetes Science and Technology | web | .pdf

2016 A Practical Approach to Glucose Abnormalities in Cystic Fibrosis GC Jones, CAR Sainsbury | web | .pdf

2016 Is all hypoglycaemia treated as equal? An observational study of how the type of diabetes and treatment prescribed prior to admission influences quality of treatment of inpatient hypoglycaemia GC Jones, J Khan, CAR Sainsbury | web | .pdf

2016 Stroke and diabetes: a dangerous liaison SL Macpherson, C Sainsbury, J Dawson, GC Jones | web | .pdf

2016 Living with asthma and chronic obstructive airways disease: using technology to support self-management – an overview. D Morrison,FS Mair, L Yardley, S Kirby, M Thomas | web

2016 Patterns and impact of hypoglycemia, hyperglycemia, and glucose variability on inpatients with insulin-treated cystic fibrosis-related diabetes GC Jones, ZM Chong, J Gilmour, C Matheson, G MacGregor, C Sainsbury | web | .pdf

2016 Metformin increases cortisol regeneration by 11βHSD1 in obese men with and without type 2 diabetes mellitus Anderson AJ, Andrew R, Homer NZ, Jones GC, Smith K, Livingstone DE, Walker BR, Stimson RH | web

2016 Inpatient glycemic variability and long-term mortality in hospitalized patients with type 2 diabetes JG Timmons, SG Cunningham, CAR Sainsbury, GC Jones Journal of Diabetes and its Complications

2016 Evaluation of a combination of SGLT2 inhibitor and GLP-1 receptor agonist treatment in type 2 diabetes Hayden J, Huang F, McConnell LMJ, Sainsbury CAR, Jones GC Diabetes & Primary Care 18 (3): 135-138

2016 Managing multimorbidity in primary care in patients with chronic respiratory conditions. npj Primary Care Respiratory Medicine, 26, 16043. D Morrison,K Agur, S Mercer, A Eiras, JI González-Montalvo, K Gruffydd-Jones Primary Care Respiratory Medicine, 26, 16043

2016 Experience of and predictors of response to dapagliflozin in a real-life cohort of people with type 2 diabetes Huang F, Hayden J, McConnell LMJ, Sainsbury CAR, Jones GC Journal of Diabetes Nursing 20 (7): 238-243

2015 Capillary blood glucose monitoring, inpatient hypoglycaemia and quality of care GC Jones, CG Perry, A Monaghan, B Kennon, CAR Sainsbury British Journal of Diabetes 15 (1), 24-26 (pdf)

2015 Comment on ‘A justification for less restrictive guidelines on the use of metformin in stable chronic renal failure’ GC Jones, CAR Sainsbury Diabetic Medicine 32 (2), 287-287

2015 Longitudinal Blood Pressure Control, Long-Term Mortality, and Predictive Utility of Serum Liver Enzymes and Bilirubin in Hypertensive Patients. L McCallum, J Panniyammakal, CE Hastie, J Hewitt, R Patel, GC Jones, S Muir, M Walters, N Sattar, AF Dominiczak, S Padmanabhan Hypertension 66 (1), 37-43 (pdf)

2014 Trends in recorded capillary blood glucose and hypoglycaemia in hospitalised patients with diabetes GC Jones, H Casey, CG Perry, B Kennon, CAR Sainsbury. Diabetes research and clinical practice 104 (1), 79-83

2014 Dipeptidyl peptidase 4 inhibitors in routine clinical practice: experiences from a Scottish teaching hospital AL Brown, CR Sainsbury, C Fenelon, AB Mullen, GC Jones British Journal of Diabetes 14 (4), 134-137 (pdf)

2014 Numerical simulation of blood flow and pressure drop in the pulmonary arterial and venous circulation MU Qureshi, GDA Vaughan, C Sainsbury, M Johnson, CS Peskin, MS Olufsen, NA Hill Biomechanics and modeling in mechanobiology 13 (5), 1137-1154

2013 Long-Term and Ultra Long–Term Blood Pressure Variability During Follow-Up and Mortality in 14 522 Patients With Hypertension. CE Hastie, P Jeemon, H Coleman, L McCallum, R Patel, J Dawson, W Sloan, P Meredith, GC Jones, S Muir, M Walters, AF Dominiczak, D Morrison, GT McInnes, S Padmanabhan Hypertension 62 (4), 698-705 (pdf)

2012 Rarefaction and blood pressure in systemic and pulmonary arteries MS Olufsen, NA Hill, GDA Vaughan, C Sainsbury, M Johnson Journal of fluid mechanics 705, 280-305

2012 Hematocrit Predicts Long-Term Mortality in a Nonlinear and Sex-Specific Manner in Hypertensive AdultsNovelty and Significance L Paul, P Jeemon, J Hewitt, L McCallum, P Higgins, M Walters, J McClure, ... Hypertension 60 (3), 631-638

2012 Boerhaave's syndrome and diabetic ketoacidosis K Mitchell, G Jones Practical Diabetes 29 (7), 268-268

2011 AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study JG Boyle, PJ Logan, GC Jones, M Small, N Sattar, JMC Connell, ... Diabetologia 54 (7), 1799-1809

presentations

2019 Predicting mortality in both diabetes and open source clinical datasets from free text entries using machine learning (natural language processing) | Diabetes Technology Society. November 2019. Washington DC | .pdf

2019 personalising risk prediction in diabetes using machine learning bridging the gap between RCT and RCD | Royal College of Physicians and Surgeons (Glasgow) | May 2019. Glasgow | .pdf

2019 data landscape presentation. march 2019 | .pdf

2018 Machine learning approaches to (i) predicting response to therapy in diabetes, (ii) data-driven diabetes subtype classification and (iii) synthetic data generation. Dundee. 210618 | .pdf | .ppt

2018 Machine-Learning (neural network) driven algorithmic classification of Type 1 or Type 2 diabetes at the time of presentation significantly outperforms experienced clinician classification. DUK. London | .pdf

2018 Parallel time-series analysis of HbA1c and Systolic BP using a recurrent neural network (RNN) stratifies for 1-year mortality in Type 2 Diabetes independent of age and parameter variability. DUK. London | .pdf

2018 Parallel time-series analysis of HbA1c, Systolic Blood Pressure and BMI using Recurrent Neural Networks stratifies for 1-year mortality in T2DM, independent of age and parameter variability. ATTD. Vienna | .pdf

2018 Time-series analysis of HbA1c using Recurrent Neural Networks stratifies for 1-year mortality in Type 1 and Type 2 Diabetes, independent of age and variability. ATTD. Vienna | .pdf

2017 MyDiabetesIQ. machine learning for decision support & outcome prediction in diabetes. Automated Clinical Epidemiology Studies workshop, University of Birmingham. 141217 | .pdf

2017 Diabetes and opiate replacement therapy (ORT). A retrospective cohort study of health care usage and clinical outcomes. H Druce, D Morrison, C Sainsbury, R Lowrie, C Ritchie, GC Jones. Oral Presentation. RCGP, London | .pdf

2017 Glucose dynamics and mortality in RRT patients: an initial report. Matthew A Rutherford, Gregory C Jones, Alan G Jardine, Patrick B Mark, Peter C Thomson, Christopher AR Sainsbury. Oral Presentation, SRA, Dunblane 2017 | .pdf

2017 Diabetes and opiate replacement therapy (ORT). A retrospective cohort study of healthcare usage and clinical outcomes. H Druce, R Lowrie, C Ritchie, D Morrison, CAR Sainsbury, GC Jones. Poster Presentation, EASD, Lisbon 2017 | .pdf

2017 Serum chloride predicts mortality risk in type 2 diabetes – analysis of 91,159 patients from the West of Scotland. Linsay McCallum, Christopher A Sainsbury, Gregory C Jones, Sandosh Padmanabhan. AHA, 2017 | .pdf

2017 Serum chloride is a mortality risk predictor in type 2 diabetes mellitus – analysis of 91,159 patients in the West of Scotland. Linsay McCallum, Christopher A Sainsbury Gregory C Jones, Sandosh Padmanabhan. Oral Presentation, ESH, Milan 2017 | .pdf

2017 Non-stimulated c-peptide is independently associated with requirement at 1 year for insulin therapy in paitnets with diabetes. A retrospective cohort study of 872 patients. EL Leighton, K Smith, SG Cunningham, CAR Sainsbury, GC Jones. Poster Presentation, ECE, Lisbon 2017 | .pdf

2017 Admission Glucose Number (AGN): a novel score associated with adverse outcomes in patients admitted with Type 2 Diabetes. CAR Sainsbury, SG Cunningham, R Srivastava, GC Jones. Poster Presentation. Diabetes UK, Manchester 2017 | .pdf

2017 Glucose variability and risk of hypoglycaemia amongst inpatients with type 2 diabetes and its relationship to drug class exposure. KM Fairhurst, SG Cunningham, CAR Sainsbury, GC Jones. Poster Presentation. Diabetes UK, Manchester 2017 | .pdf

2017 Does pre-admission HbA1c predict inpatient glucose characteristics and outcomes in patients with diabetes? M Talla, SG Cunningham, CAR Sainsbury, GC Jones. Poster Presentation. Diabetes UK. Manchester March 2017 | [.pdf](./glucose_ai_presentation_files/Diab UK HbA1c Inpatient Glucose Characteristics.pdf)

2017 Admission Glucose Number (AGN): A novel point-of-admission score associated with prolonged admission duration, and with glycaemic characteristics in patients with Type 1 Diabetes. R Maitland, R Srivastava, S Cunningham, G Jones, C Sainsbury. 2017. ATTD, Paris. Oral Presentation | .pdf

2016 Does type of diabetes, and treatment prescribed prior to admission influence quality of treatment of inpatient hypoglycaemia? CAR Sainsbury, J Khan, GC Jones. British Endocrine Society. Oral Presentation | .pdf

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