Data and analysis scripts for Wall, Wu, Harvey et al., Lancet, 2021.
"AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC"
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01462-8/fulltext
and incorporating data from Wall, Wu, et al., Lancet, 2021.
"Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination"
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01290-3/fulltext
Please cite both:
Wall EC, Wu M, Harvey R, Kelly G, Warchal S, Sawyer C, Daniels R, Adams L, Hobson P, Hatipoglu E, Ngai Y, Hussain S, Ambrose K, Hindmarsh S, Beale R, Riddell A, Gamblin S, Howell M, Kassiotis G, Libri V, Williams B, Swanton C, Gandhi S, Bauer DL. AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC. Lancet. 2021 Jul 17;398(10296):207-209. doi: 10.1016/S0140-6736(21)01462-8. Epub 2021 Jun 28. PMID: 34197809; PMCID: PMC8238446.
AND
Wall EC, Wu M, Harvey R, Kelly G, Warchal S, Sawyer C, Daniels R, Hobson P, Hatipoglu E, Ngai Y, Hussain S, Nicod J, Goldstone R, Ambrose K, Hindmarsh S, Beale R, Riddell A, Gamblin S, Howell M, Kassiotis G, Libri V, Williams B, Swanton C, Gandhi S, Bauer DLV. Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination. Lancet. 2021 Jun 19;397(10292):2331-2333. doi: 10.1016/S0140-6736(21)01290-3. Epub 2021 Jun 3. PMID: 34090624; PMCID: PMC8175044.
Available in this repository:
- Crick_Legacy_2021-24-05_B-1-617-2_PUBLIC.Rda
- Crick_Legacy_2021-12-06_B-1-617-2_AZ_PUBLIC.Rda
- Crick_Legacy_AZPfizer_2021-12-06_B-1-617-2_GeneratePlots.R
Note that the barcode/participant IDs between the Pfizer and AZ datasets overlap due to anonymisation (i.e. don't join on barcodes/IDs without appending an identifier as to which dataset they came from).