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Neurodecode provides a real-time brain signal decoding framework. The decoding performance was recognised at Microsoft Brain Signal Decoding competition with the First Prize Award (2016) after achieving high decoding accuracy. It has been applied on a couple of online decoding projects with various human brain signal types including EEG, ECoG and LFP, and on several acquisition systems including AntNeuro eego, g.tec gUSBamp, BioSemi ActiveTwo, BrainProducts actiCHamp and Wearable Sensing. The decoding runs at approximately 15 classifications per second(cps) on a 4th-gen i7 laptop with 64-channel setup at 512 Hz sampling rate. High-speed decoding up to 200 cps was achieved using process-interleaving technique on 8 cores. It has been tested on both Linux and Windows using Python 3.7.

The underlying data communication is based on Lab Streaming Layer (LSL) which provides sub-millisecond time synchronization accuracy. Any signal acquisition system supported by native LSL or OpenVibe is also supported by Neurodecode. Since the data communication is based on TCP, signals can be also transmitted wirelessly. For more information about LSL, please visit:

Important update

The GUI version of this software is now being developed and maintained by Fondation Campus Biotech Geneva (FCBG)

Check out this documentation

Important modules


The base module for acquiring signals used by other modules such as Decoder, StreamViewer and StreamRecorder.


Visualize signals in real time with spectral filtering, common average filtering options and real-time FFT.


Record signals into fif format, a standard format mainly used in MNE EEG analysis library.


Replay the recorded signals in real time as if it was transmitted from a real acquisition server.


This folder contains decoder and trainer modules. Currently, LDA, regularized LDA, Random Forests, and Gradient Boosting Machines are supported as the classifier type. Neural Network-based decoders are currently under experiment.


Contains some basic protocols for training and testing. Google Glass visual feedback is supported through USB communication.


Triggers are used to mark event (stimulus) timings during the recording. This folder contains common trigger event definition files.


Contains various utilities.


Anaconda is recommended for easy installation of Python environment.

Neurodecode depends on following packages:

  • scipy
  • numpy
  • PyQt5
  • scikit-learn
  • pylsl
  • mne 0.14 or later
  • matplotlib 2.1.0 or later
  • pyqtgraph
  • opencv-python
  • pyserial
  • future
  • configparser
  • xgboost
  • psutil

Optional but strongly recommended:

OpenVibe supports a wide range of acquisition servers and all acquisition systems supported by OpenVibe are supported by Neurodecode through LSL. Make sure you tick the checkbox "LSL_EnableLSLOutput" in Preferences when you run acquisition server. This will stream the data through the LSL network from which Neurodecode receives data.


Clone the repository:

git clone

Run setup script:

python develop

Add "scripts" directory to PATH environment variable for convenient access to commonly used scripts.

For Windows users, increase timer resolution

The default timer resolution in some Windows versions is 16 ms, which can limit the precision of timings. It is recommended to run the following tool and set the resolution to 1 ms or lower:

Hardware triggering without legacy parallel port

We have also developed an Arduino-based triggering system as we wanted to send triggers to a parallel port using standard USB ports. We achieved sub-millisecond extra latency compared to physical parallel port (150 +- 25 us). Experimental results using oscilloscope can be found in "doc" folder. The package can be downloaded by:

git clone

The customized firmware should be installed on Arduino Micro and the circuit design included in the document folder should be printed to a circuit board.

For g.USBamp users

The following customized acquisition server is needed instead of default LSL app to receive the trigger channel as part of signal streaming channels:

git clone

because the default gUSBamp LSL server do not stream event channel as part of the signal stream but as a separate server. The customized version supports simultaneous signal+event channel streaming.

For AntNeuro eego users

Use the OpenVibe acquisition server and make sure to check "LSL output" in preference. If you don't see "eego" from the device selection, it's probably because you didn't install the additional drivers when you installed OpenVibe.

To do

  • GUI (in progress)
  • Tutorial
  • More cpu-efficient decoder class
  • Numba optimization

There are still plenty of possibilities to optimize the speed in many parts of the code. Any contribution is welcome. Please contact for any comment / feedback.

Copyright and license

The codes are released under GNU General Public License.


A framework for real-time brain-machine interface



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