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read_parsers.hh
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read_parsers.hh
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//
// This file is part of khmer, http://github.com/ged-lab/khmer/, and is
// Copyright (C) Michigan State University, 2009-2013. It is licensed under
// the three-clause BSD license; see doc/LICENSE.txt.
// Contact: khmer-project@idyll.org
//
#ifndef READ_PARSERS_HH
#define READ_PARSERS_HH
#include <cstdarg>
#include <iostream>
#include <string>
#include <utility>
#include <stdlib.h>
extern "C"
{
#include <regex.h>
}
#include "zlib.h"
#include "bzlib.h"
#include "khmer.hh"
#include "khmer_config.hh"
#include "thread_id_map.hh"
#include "trace_logger.hh"
#include "perf_metrics.hh"
namespace khmer
{
namespace read_parsers
{
class InvalidReadFileFormat: public khmer:: khmer_file_exception
{
public:
InvalidReadFileFormat(
char const * exc_name,
char const * reason = NULL,
char const * evidence = NULL
);
virtual char const * what( ) const throw( );
protected:
char _reason[ CHAR_MAX ];
};
class InvalidFASTAFileFormat: public InvalidReadFileFormat
{
public:
public:
InvalidFASTAFileFormat(
char const * reason = NULL,
char const * evidence = NULL
);
};
class InvalidFASTQFileFormat: public InvalidReadFileFormat
{
public:
public:
InvalidFASTQFileFormat(
char const * reason = NULL,
char const * evidence = NULL
);
};
struct CacheSegmentUnavailable : public khmer_exception {
};
struct CacheSegmentBoundaryViolation : public khmer_exception {
};
struct InvalidCacheSizeRequested : public khmer_exception {
};
struct NoMoreReadsAvailable : public khmer_exception {
};
struct UnknownPairReadingMode : public khmer_exception {
};
struct InvalidReadPair : public khmer_exception {
};
#ifdef WITH_INTERNAL_METRICS
struct StreamReaderPerformanceMetrics : public IPerformanceMetrics {
enum {
MKEY_TIME_READING
};
uint64_t numbytes_read;
uint64_t clock_nsecs_reading;
uint64_t cpu_nsecs_reading;
StreamReaderPerformanceMetrics( );
virtual ~StreamReaderPerformanceMetrics( );
virtual void accumulate_timer_deltas( uint32_t metrics_key );
};
#endif
struct IStreamReader {
#ifdef WITH_INTERNAL_METRICS
StreamReaderPerformanceMetrics pmetrics;
#endif
IStreamReader(int const fd );
virtual ~IStreamReader( );
size_t const get_memory_alignment( ) const;
bool const is_at_EOS_ATOMIC( );
virtual uint64_t const read_into_cache(
uint8_t * const cache, uint64_t const cache_size
) = 0;
protected:
size_t _alignment;
size_t _max_aligned;
bool _at_eos;
void _set_EOS_ATOMIC( );
int _file_descriptor;
};
struct RawStreamReader : public IStreamReader {
RawStreamReader( int const fd, size_t const alignment = 0 );
virtual ~RawStreamReader( );
virtual uint64_t const read_into_cache(
uint8_t * const cache, uint64_t const cache_size
);
};
struct GzStreamReader : public IStreamReader {
GzStreamReader( int const fd );
virtual ~GzStreamReader( );
virtual uint64_t const read_into_cache(
uint8_t * const cache, uint64_t const cache_size
);
private:
gzFile _stream_handle;
};
struct Bz2StreamReader : public IStreamReader {
Bz2StreamReader( int const fd );
virtual ~Bz2StreamReader( );
virtual uint64_t const read_into_cache(
uint8_t * const cache, uint64_t const cache_size
);
private:
FILE * _stream_handle;
BZFILE * _block_handle;
};
#ifdef WITH_INTERNAL_METRICS
struct CacheSegmentPerformanceMetrics : public IPerformanceMetrics {
enum {
MKEY_TIME_WAITING_TO_SET_SA_BUFFER,
MKEY_TIME_WAITING_TO_GET_SA_BUFFER,
MKEY_TIME_WAITING_TO_FILL_FROM_STREAM,
MKEY_TIME_FILLING_FROM_STREAM,
MKEY_TIME_IN_SYNC_BARRIER
};
uint64_t numbytes_filled_from_stream;
uint64_t numbytes_copied_from_ca_buffer;
uint64_t numbytes_reserved_as_ca_buffer;
uint64_t numbytes_copied_to_caller_buffer;
uint64_t clock_nsecs_waiting_to_set_ca_buffer;
uint64_t cpu_nsecs_waiting_to_set_ca_buffer;
uint64_t clock_nsecs_waiting_to_get_ca_buffer;
uint64_t cpu_nsecs_waiting_to_get_ca_buffer;
uint64_t clock_nsecs_waiting_to_fill_from_stream;
uint64_t cpu_nsecs_waiting_to_fill_from_stream;
uint64_t clock_nsecs_filling_from_stream;
uint64_t cpu_nsecs_filling_from_stream;
uint64_t clock_nsecs_in_sync_barrier;
uint64_t cpu_nsecs_in_sync_barrier;
CacheSegmentPerformanceMetrics( );
virtual ~CacheSegmentPerformanceMetrics( );
virtual void accumulate_timer_deltas( uint32_t metrics_key );
virtual void accumulate_metrics(
CacheSegmentPerformanceMetrics &source
);
protected:
uint32_t _accumulated_count;
};
#endif
struct CacheManager {
CacheManager(
IStreamReader & stream_reader,
uint32_t const number_of_threads,
uint64_t const cache_size,
uint8_t const trace_level =
khmer:: get_active_config( ).get_input_buffer_trace_level( )
);
~CacheManager( );
// Returns true, if current thread has more bytes to consume.
// Blocks, if current thread has no more bytes to consume,
// but other threads still do. (Synchronization barrier.)
// Returns false, if no threads have more bytes to consume.
bool const has_more_data( );
uint64_t const get_bytes(
uint8_t * const buffer, uint64_t buffer_len
);
uint64_t const whereis_cursor( void );
bool const is_cursor_in_ca_buffer( void );
void split_at( uint64_t const pos );
uint64_t const get_fill_id( );
private:
struct CacheSegment {
bool avail;
uint32_t thread_id;
uint64_t size;
size_t alignment;
uint8_t * memory;
uint64_t cursor;
bool cursor_in_ca_buffer;
std:: string ca_buffer;
uint64_t fill_id;
bool found_EOS;
#ifdef WITH_INTERNAL_METRICS
CacheSegmentPerformanceMetrics pmetrics;
#endif
TraceLogger trace_logger;
CacheSegment(
uint32_t const thread_id,
uint64_t const size,
size_t const alignment = 0,
uint8_t const trace_level =
khmer:: get_active_config( ).get_input_buffer_trace_level( )
);
~CacheSegment( );
}; // struct CacheSegment
uint8_t _trace_level;
IStreamReader & _stream_reader;
uint32_t _number_of_threads;
ThreadIDMap _thread_id_map;
size_t _alignment;
uint64_t _segment_size;
CacheSegment ** _segments;
uint32_t _segment_ref_count;
uint32_t _segment_to_fill;
uint64_t _fill_counter;
// Copyaside buffers.
std:: map< uint64_t, std:: string > _ca_buffers;
uint32_t _ca_spin_lock;
// Extends or refills segment for current thread, as needed.
void _perform_segment_maintenance(
CacheSegment & segment
);
uint64_t _get_fill_counter_ATOMIC( );
void _increment_fill_counter_ATOMIC( );
bool const _check_segment_to_fill_ATOMIC(
uint32_t const thread_id
);
void _select_segment_to_fill_ATOMIC( );
CacheSegment & _get_segment( bool const higher = false );
void _fill_segment_from_stream(
CacheSegment & segment
);
void _increment_segment_ref_count_ATOMIC( );
void _decrement_segment_ref_count_ATOMIC( );
uint32_t const _get_segment_ref_count_ATOMIC( );
}; // struct CacheManager
struct Read {
std:: string name;
std:: string annotations;
std:: string sequence;
std:: string accuracy;
// TODO? Add description field.
uint64_t bytes_consumed;
inline void reset ( )
{
name.clear( );
annotations.clear( );
sequence.clear( );
accuracy.clear( );
bytes_consumed = 0;
}
};
typedef std:: pair< Read, Read > ReadPair;
#ifdef WITH_INTERNAL_METRICS
struct ParserPerformanceMetrics: public IPerformanceMetrics {
uint64_t numlines_copied;
uint64_t numreads_parsed_total;
uint64_t numreads_parsed_valid;
ParserPerformanceMetrics( );
virtual ~ParserPerformanceMetrics( );
virtual void accumulate_timer_deltas( uint32_t metrics_key );
};
#endif
struct IParser {
enum {
PAIR_MODE_ALLOW_UNPAIRED = 0,
PAIR_MODE_IGNORE_UNPAIRED,
PAIR_MODE_ERROR_ON_UNPAIRED
};
static IParser * const get_parser(
std:: string const &ifile_name,
uint32_t const number_of_threads =
khmer:: get_active_config( ).get_number_of_threads( ),
uint64_t const cache_size =
khmer:: get_active_config( ).get_reads_input_buffer_size( ),
uint8_t const trace_level =
khmer:: get_active_config( ).get_reads_parser_trace_level( )
);
IParser(
IStreamReader &stream_reader,
uint32_t const number_of_threads =
khmer:: get_active_config( ).get_number_of_threads( ),
uint64_t const cache_size =
khmer:: get_active_config( ).get_reads_input_buffer_size( ),
uint8_t const trace_level =
khmer:: get_active_config( ).get_reads_parser_trace_level( )
);
virtual ~IParser( );
inline int uuid( )
{
return _uuid;
}
inline bool is_complete( )
{
return !_cache_manager.has_more_data( ) && !_get_state( ).buffer_rem;
}
// Note: 'get_next_read' exists for legacy reasons.
// In the long term, it should be eliminated in favor of direct use of
// 'imprint_next_read'. A potentially costly copy-by-value happens
// upon return.
// TODO: Eliminate all calls to 'get_next_read'.
inline Read get_next_read( )
{
Read the_read;
imprint_next_read( the_read );
return the_read;
}
virtual void imprint_next_read( Read &the_read );
virtual void imprint_next_read_pair(
ReadPair &the_read_pair,
uint8_t mode = PAIR_MODE_ERROR_ON_UNPAIRED
);
protected:
struct ParserState {
// TODO: Set buffer size from Config.
static uint64_t const BUFFER_SIZE = 127;
bool at_start;
uint64_t fill_id;
std:: string line;
bool need_new_line;
uint8_t buffer[ BUFFER_SIZE + 1 ];
uint64_t buffer_pos;
uint64_t buffer_rem;
#ifdef WITH_INTERNAL_METRICS
ParserPerformanceMetrics pmetrics;
#endif
TraceLogger trace_logger;
ParserState( uint32_t const thread_id, uint8_t const trace_level );
~ParserState( );
}; // struct ParserState
// TODO: Use a 16-octet IETF RFC 4122 UUID or equivalent.
int _uuid;
uint8_t _trace_level;
CacheManager _cache_manager;
uint32_t _number_of_threads;
ThreadIDMap _thread_id_map;
bool _unithreaded;
ParserState ** _states;
regex_t _re_read_2_nosub;
regex_t _re_read_1;
regex_t _re_read_2;
void _copy_line( ParserState &state );
virtual void _parse_read( ParserState &, Read & ) = 0;
#if (0)
void _imprint_next_read_pair_in_allow_mode(
ReadPair &the_read_pair
);
#endif
void _imprint_next_read_pair_in_ignore_mode(
ReadPair &the_read_pair
);
void _imprint_next_read_pair_in_error_mode(
ReadPair &the_read_pair
);
bool _is_valid_read_pair(
ReadPair &the_read_pair, regmatch_t &match_1, regmatch_t &match_2
);
inline ParserState &_get_state( )
{
uint32_t thread_id = _thread_id_map.get_thread_id( );
ParserState * state_PTR = NULL;
if(!( NULL != _states )) {
throw khmer_exception();
}
state_PTR = _states[ thread_id ];
if (NULL == state_PTR) {
_states[ thread_id ] =
new ParserState( thread_id, _trace_level );
state_PTR = _states[ thread_id ];
}
return *state_PTR;
}
}; // struct IParser
struct FastaParser : public IParser {
FastaParser(
IStreamReader & stream_reader,
uint32_t const number_of_threads,
uint64_t const cache_size,
uint8_t const trace_level
);
virtual ~FastaParser( );
virtual void _parse_read( ParserState &, Read &);
};
struct FastqParser : public IParser {
FastqParser(
IStreamReader & stream_reader,
uint32_t const number_of_threads,
uint64_t const cache_size,
uint8_t const trace_level
);
virtual ~FastqParser( );
virtual void _parse_read( ParserState &, Read &);
};
inline PartitionID _parse_partition_id(std::string name)
{
PartitionID p = 0;
const char * s = name.c_str() + name.length() - 1;
if (!(*(s + 1) == (unsigned int) NULL)) {
throw khmer_exception();
}
while(*s != '\t' && s >= name.c_str()) {
s--;
}
if (*s == '\t') {
p = (PartitionID) atoi(s + 1);
} else {
std::cerr << "consume_partitioned_fasta barfed on read " << name << "\n";
throw khmer_exception();
}
return p;
}
} // namespace read_parsers
} // namespace khmer
#endif // READ_PARSERS_HH
// vim: set ft=cpp sts=4 sw=4 tw=80: