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Algorithm for finding direct interactor of a given node with specified modifications.

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Druggable Interactor Finder Build Status Documentation Status zenodo

A pipeline for identifying the most notable druggable interactors of a target within a e(BE:L) generated Knowledge Graph. This feature will be integrated into the e(BE:L) package in the future.

Installation Current version on PyPI Stable Supported Python Versions MIT License

$ pip install drugintfinder

Usage

Finding the direct causal interactors of the phosphorylated MAPT protein:

$ dif find MAPT -n protein -e causal -m pho

Finding the direct causal interactors of the phosphorylated MAPT protein which are druggable:

$ dif find MAPT -n protein -e causal -m pho -d

Creating a table of various parameters for each interactor by which to rank them:

$ dif rank MAPT -m pho

Disclaimer

The Druggable Interactor finder is a resource developed in an academic capacity funded by the MAVO project and thus comes with no warranty or guarantee of maintenance or support.

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Algorithm for finding direct interactor of a given node with specified modifications.

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