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Release 10.0
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@jmillanacosta
jmillanacosta committed Jul 12, 2023
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30 changes: 28 additions & 2 deletions internal-dev/bao-ext.owl
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xmlns:dc="http://purl.org/dc/elements/1.1/">
<owl:Ontology rdf:about="http://enanomapper.github.io/ontologies/internal/bao-ext.owl">
<dc:contributor>Egon Willighagen</dc:contributor>
<dc:contributor>Javier Millan Acosta</dc:contributor>
</owl:Ontology>


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<rdfs:label xml:lang="en">IC50 (Hill model)</rdfs:label>
</owl:Class>



<!-- http://purl.enanomapper.net/onto/ENM_8100002 -->

<owl:Class rdf:about="http://purl.enanomapper.net/onto/ENM_8100002">
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</owl:Class>


<!-- http://purl.enanomapper.org/onto/ENM_9000268 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_9000268">
<rdfs:subClassOf rdf:resource="http://www.bioassayontology.org/bao#BAO_0010019"/>
<rdfs:label xml:lang="en">Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) assay</rdfs:label>
<rdfs:label xml:lang="en">SDS-PAGE assay</rdfs:label>
<obo:IAO_0000115>Assay used to separate proteins according to their electrophoretic mobility, which is a function of their dimensions, conformation and charge.</obo:IAO_0000115>
</owl:Class>

<!-- http://purl.enanomapper.org/onto/ENM_9000266 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_9000266">
<rdfs:subClassOf rdf:resource="http://www.bioassayontology.org/bao#BAO_0003009"/>
<obo:IAO_0000115>Cell proliferation assay used to assess cytotoxicity. It measures the extracellular conversion of tetrazolium salt WST-8 to formazan products by intracellular mitochondrial oxidoreductases in viable cells.</obo:IAO_0000115>
<rdfs:label xml:lang="en">WST-8</rdfs:label>
<rdfs:label xml:lang="en">WST-8 Cell Proliferation Assay</rdfs:label>
</owl:Class>

<!-- http://purl.enanomapper.org/onto/ENM_9000269 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_9000269">
<rdfs:subClassOf rdf:resource="http://www.bioassayontology.org/bao#BAO_0000015"/>
<obo:IAO_0000115>Bioassay which measures the opposition to the flow of electrical current (impedance) through tissues, cell monolayers and single cells when an external alternating current (AC) field is applied.
This assay is label-free and constitutes a reliable alternative with the potential to become a method of choice for the initial screening of toxic effects in nanomaterials. Impedance-based monitoring takes advantage of the passive properties of an object, which occur when the object is composed of dissipative elements, such as ohmic resistors or conservative elements, such as capacitances and inductances . It measures the opposition to the flow of electrical current (impedance) through tissues, cell monolayers and single cells when an external alternating current (AC) field is applied.</obo:IAO_0000115>
<rdfs:label xml:lang="en">Bioimpedance assay</rdfs:label>
<rdfs:label xml:lang="en">Impedance-based cell assay</rdfs:label>
</owl:Class>

</rdf:RDF>

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2 changes: 2 additions & 0 deletions internal-dev/catalog-v001.xml
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<?xml version="1.0" encoding="UTF-8" standalone="no"?>
<catalog prefer="public" xmlns="urn:oasis:names:tc:entity:xmlns:xml:catalog"/>
21 changes: 21 additions & 0 deletions internal-dev/endpoints.owl
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</owl:Class>



<!-- http://purl.enanomapper.org/onto/ENM_0000051 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_0000051">
<rdfs:subClassOf rdf:resource="http://www.bioassayontology.org/bao#BAO_0002162"/>
<obo:IAO_0000115>The effective concentration which produces 10% of the maximum possible response. </obo:IAO_0000115>
<rdfs:label xml:lang="en">EC10</rdfs:label>
</owl:Class>



<!-- http://purl.enanomapper.org/onto/ENM_0000052 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_0000052">
<rdfs:subClassOf rdf:resource="http://www.bioassayontology.org/bao#BAO_0002162"/>
<obo:IAO_0000115>The effective concentration that produces 20% of the maximum possible response. </obo:IAO_0000115>
<rdfs:label xml:lang="en">EC20</rdfs:label>
</owl:Class>



<!-- http://purl.enanomapper.org/onto/ENM_0000053 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_0000053">
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24 changes: 24 additions & 0 deletions internal-dev/ncit-ext.owl
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<?xml version="1.0"?>
<rdf:RDF xmlns="http://purl.enanomapper.net/onto/internal/ncit-ext.owl#"
xml:base="http://purl.enanomapper.net/onto/internal/ncit-ext.owl"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:xml="http://www.w3.org/XML/1998/namespace"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:obo="http://purl.obolibrary.org/obo/"
xmlns:dc="http://purl.org/dc/elements/1.1/">
<owl:Ontology rdf:about="http://enanomapper.github.io/ontologies/internal/ncit-ext.owl">
<dc:contributor>Javier Millan Acosta</dc:contributor>
</owl:Ontology>


<!-- http://purl.enanomapper.org/onto/ENM_9000267 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_9000267">
<rdfs:subClassOf rdf:resource="http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C119826"/>
<rdfs:isDefinedBy>Pulmonary exposure is performed by instillation of test substance dispersed in a liquid vehicle. The liquid is delivered/blown into the lungs of sedated animals. The exposure is a bolus exposure and the dose is delivered within seconds.</rdfs:isDefinedBy>
<rdfs:label xml:lang="en">Pulmonary instillation</rdfs:label>
</owl:Class>

</rdf:RDF>
9 changes: 9 additions & 0 deletions internal-dev/obi-ext.owl
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<owl:Ontology rdf:about="http://enanomapper.github.io/ontologies/internal/obi-ext.owl">
<dc:contributor>Laurent Winckers</dc:contributor>
<dc:contributor>Javier Millan Acosta</dc:contributor>
<dc:license>CC-BY 4.0 https://creativecommons.org/licenses/by/4.0/</dc:license>
<rdfs:comment>This ontology contains proposed extensions to the Ontology for Biomedical Investigations, which in due course will be submitted to the OBI. </rdfs:comment>
</owl:Ontology>
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</owl:Class>


<!-- http://purl.enanomapper.org/onto/ENM_9000265 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_9000265">
<rdfs:subClassOf rdf:resource="http://purl.enanomapper.org/onto/ENM_9000009"/>
<rdfs:label xml:lang="en">Ferric Reduction Ability of Serum</rdfs:label>
<rdfs:label xml:lang="en">FRAS</rdfs:label>
<obo:IAO_0000115>Assay measuring the surface reactivity of nanomaterials under physiological conditions to determine their dose-dependent oxidative damage</obo:IAO_0000115>
</owl:Class>

</rdf:RDF>
6 changes: 6 additions & 0 deletions internal-dev/opentox/catalog-v001.xml
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<?xml version="1.0" encoding="UTF-8" standalone="no"?>
<catalog prefer="public" xmlns="urn:oasis:names:tc:entity:xmlns:xml:catalog">
<group id="Folder Repository, directory=, recursive=true, Auto-Update=true, version=2" prefer="public" xml:base="">
<uri id="Automatically generated entry, Timestamp=1462990308186" name="http://www.opentox.org/api/1.2" uri="opentox.owl"/>
</group>
</catalog>
2 changes: 1 addition & 1 deletion internal-dev/pato-ext.owl
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<!-- http://purl.enanomapper.org/onto/ENM_1200001 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_1200000">
<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_1200001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0050001"/>
<rdfs:isDefinedBy>The amount of dissolved substance versus time (determined by the crystal forces) as an experimental value, where solid particles (usually crystalline) are released into solution as individual free molecules.</rdfs:isDefinedBy>
<rdfs:label xml:lang="en">Dissolution rate</rdfs:label>
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9 changes: 4 additions & 5 deletions internal/bao-ext.owl
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</rdfs:subClassOf>
<obo:IAO_0000115>An IC50 calculated with the Hill model fitting algorithm.</obo:IAO_0000115>
<rdfs:label xml:lang="en">IC50 (Hill model)</rdfs:label>
</owl:Class>

</owl:Class>
<!-- http://purl.enanomapper.net/onto/ENM_8100002 -->

<owl:Class rdf:about="http://purl.enanomapper.net/onto/ENM_8100002">
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<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_9000013">
<rdfs:subClassOf rdf:resource="http://www.bioassayontology.org/bao#BAO_0003009"/>
<obo:IAO_0000115>Cell proliferation assay used to assess cytotoxicity. It measures the extracellular conversion of tetrazolium salt WST-1 to formazan products by intracellular mitochondrial oxidoreductases in viable cells.</obo:IAO_0000115>
<rdfs:isDefinedBy>wst-1 cell proliferation assay is a sensitive and accurate assay for cell proliferation and cytotoxicity.</rdfs:isDefinedBy>
<rdfs:label xml:lang="en">WST-1</rdfs:label>
<rdfs:label xml:lang="en">WST-1 Cell Proliferation Assay</rdfs:label>
</owl:Class>


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<rdfs:label xml:lang="en">SDS-PAGE assay</rdfs:label>
<obo:IAO_0000115>Assay used to separate proteins according to their electrophoretic mobility, which is a function of their dimensions, conformation and charge.</obo:IAO_0000115>
</owl:Class>

<!-- http://purl.enanomapper.org/onto/ENM_9000266 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_9000266">
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62 changes: 0 additions & 62 deletions internal/npo-ext.owl
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<rdfs:label xml:lang="en">cobalt ferrite</rdfs:label>
</owl:Class>

<!-- http://purl.enanomapper.org/onto/ENM_9000258 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_9000258">
<rdfs:subClassOf rdf:resource="http://purl.bioontology.org/ontology/npo#NPO_354"/>
<obo:IAO_0000115>A PATROLS-donated compound multiwall carbon nanotube.</obo:IAO_0000115>
<rdfs:label xml:lang="en">JRCNM40011a</rdfs:label>
<synonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NRCWE-006</synonym>
</owl:Class>


<!-- http://purl.enanomapper.org/onto/ENM_9000259 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_9000259">
<rdfs:subClassOf rdf:resource="http://purl.bioontology.org/ontology/npo#NPO_1892"/>
<obo:IAO_0000115>A silver nanoparticle from the JRC library.</obo:IAO_0000115>
<rdfs:label xml:lang="en">JRCNM03001a</rdfs:label>
</owl:Class>


<!-- http://purl.enanomapper.org/onto/ENM_9000260 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_9000260">
<rdfs:subClassOf rdf:resource="http://purl.bioontology.org/ontology/npo#NPO_1892"/>
<obo:IAO_0000115>A silver nanoparticle from the JRC library.</obo:IAO_0000115>
<rdfs:label xml:lang="en">JRCNM03002a</rdfs:label>
</owl:Class>


<!-- http://purl.enanomapper.org/onto/ENM_9000261 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_9000261">
<rdfs:subClassOf rdf:resource="http://purl.bioontology.org/ontology/npo#NPO_354"/>
<obo:IAO_0000115>A multiwall carbon nanotube from the JRC library.</obo:IAO_0000115>
<rdfs:label xml:lang="en">JRCNM04002a</rdfs:label>
</owl:Class>


<!-- http://purl.enanomapper.org/onto/ENM_9000262 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_9000262">
<rdfs:subClassOf rdf:resource="http://purl.bioontology.org/ontology/npo#NPO_354"/>
<obo:IAO_0000115>A multiwall carbon nanotube from the JRC library.</obo:IAO_0000115>
<rdfs:label xml:lang="en">JRCNM04003a</rdfs:label>
</owl:Class>


<!-- http://purl.enanomapper.org/onto/ENM_9000263 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_9000263">
<rdfs:subClassOf rdf:resource="http://purl.bioontology.org/ontology/npo#NPO_943"/>
<obo:IAO_0000115>A singlewall carbon nanotube from the JRC library.</obo:IAO_0000115>
<rdfs:label xml:lang="en">JRCNM46000a</rdfs:label>
</owl:Class>


<!-- http://purl.enanomapper.org/onto/ENM_9000264 -->

<owl:Class rdf:about="http://purl.enanomapper.org/onto/ENM_9000264">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_134404"/>
<obo:IAO_0000115>A graphene nanoparticle from the JRC library.</obo:IAO_0000115>
<rdfs:label xml:lang="en">JRCNM48001a</rdfs:label>
</owl:Class>

</rdf:RDF>

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xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:obo="http://purl.obolibrary.org/obo/"
xmlns:dc="http://purl.org/dc/elements/1.1/">

<owl:Ontology rdf:about="http://enanomapper.github.io/ontologies/internal/obi-ext.owl">
<dc:contributor>Laurent Winckers</dc:contributor>
<dc:contributor>Javier Millan Acosta</dc:contributor>
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