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v1.11.0

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@epi2melabs-bot epi2melabs-bot released this 12 Feb 22:36
· 194 commits to master since this release

Changed

  • Add an additional whatshap haplotag process after the final VCF phasing.
  • Updates to the phasing subworkflow significantly impact the runtime and storage requirement for the workflow, as detailed here.
  • Several performance improvements which should noticeably reduce the running time of the workflow

Fixed

  • Updated the version of Straglr, which addresses the following:
    • Repeats can now be called in RFC1
    • Start position of called STRs is 1-based rather than 0-based
    • VCF headers now match those in the FORMAT field
  • Generate allChromosomes.bed using samtools faidx index instead of pyfaidx, to avoid a KeyError
  • Inconsistent file ownership of bundled Clair3 model files which could lead to subuid errors in some environments