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CNVkit for RNA-seq: import-rna -f counts not working #437

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bynjh007 opened this issue Apr 16, 2019 · 2 comments
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CNVkit for RNA-seq: import-rna -f counts not working #437

bynjh007 opened this issue Apr 16, 2019 · 2 comments

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@bynjh007
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Hi,
I am trying to use CNVkit to infer CNV profiles from RNA-seq. Because I don't have CNV-RNA correlation data (mouse dataset), I tried to compare how much the results can be different between with and without "-c" for example TCGA data (106 samples) that you provided. But all of the log2 values in ".cnr" files for 106 samples are zero in both results (with and without "-c"). Did I miss something?
Here are my commands:
"cnvkit.py import-rna -f counts -c tcga-skcm.cnv-expr-corr.tsv -g ensembl-gene-info.hg38.tsv -o {output} --out-dir {output_dir} {input_cnt}"

"cnvkit.py import-rna -f counts -g ensembl-gene-info.hg38.tsv -o {output} --out-dir {output_dir} {input_cnt}"

input_cnt: ex) TCGA-BF-A1PU-01.txt

Thanks!
Jinhyuk

@etal
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etal commented Apr 17, 2019

I think the -f counts format is not working at the moment, see #425

@etal etal added the bug label Apr 17, 2019
@etal etal added the rna label May 27, 2019
@etal
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etal commented Nov 29, 2019

It looks like the -f counts format works correctly in the development version now. I'll roll another release.

@etal etal closed this as completed Nov 29, 2019
@etal etal changed the title CNVkit for RNA-seq CNVkit for RNA-seq: import-rna -f counts not working Nov 29, 2019
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