fallahi-sichani-lab/probabilisticDrugResponse
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Custom MATLAB scripts for probabilistic simulation of drug response in heterogeneous tumors cell populations, as presented in Figures 1, 2 and 4 of the manuscript: Comandante-Lou N, Khaliq M, Venkat D, Manikkam M, Fallahi-Sichani M. Phenotype-based probabilistic analysis of heterogeneous responses to cancer drugs and their combination efficacy. PLoS Comput Biol. 2020 Feb 21;16(2):e1007688. doi: 10.1371/journal.pcbi.1007688. PMID: 32084135; PMCID: PMC7055924. This work was supported by awards from the Elsa Pardee Foundation and V Foundation for Cancer Research V2017-011, Department of Defense PRCRP Career Development Award W81XWH1810427, NIH grants R00-CA194163 and R35-GM133404 (to MFS), P30-CA046592 (University of Michigan Rogel Cancer Center), Rackham International Student Fellowship (to NCL), and NCI Training Grant award T32-CA009676 (to MK).
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Phenotype-Based Probabilistic Analysis of Heterogeneous Responses to Cancer Drugs and Their Combination Efficacy
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