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JohnsonKinaseData

JohnsonKinaseData is an R/ExperimentHub package providing access to position specific weight matrices (PWMs) for 303 human serine/threonine kinases originally published in Johnson et al. 2023.

The package includes functionallity to match PWMs against phosphosites and to convert PWM scores into percentile ranks using a background score distribution.

All data records are available under https://zenodo.org/records/10628874 according to open data standards and licenses under the Creative Commons Attribution 4.0 International license (CC-BY 4.0).

References

Johnson, J.L., Yaron, T.M., Huntsman, E.M. et al. An atlas of substrate specificities for the human serine/threonine kinome. Nature 613, 759–766 (2023). https://doi.org/10.1038/s41586-022-05575-3

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