Skip to content

Commit

Permalink
CHANGE: intro.rst: Functionalities -> Features
Browse files Browse the repository at this point in the history
  • Loading branch information
thiago-miller committed Dec 30, 2019
1 parent 260adfe commit e4127fe
Showing 1 changed file with 13 additions and 10 deletions.
23 changes: 13 additions & 10 deletions docs/intro.rst
Original file line number Diff line number Diff line change
Expand Up @@ -26,8 +26,8 @@ Got interested? For a more detailed explanation about what is
a retrocopy at all, please see our section :ref:`Retrocopy in a
nutshell <chap_retrocopy>`.

Functionalities
===============
Features
========

When detecting retrocopy mobilization, sideRETRO can annotate
several other features related to the event:
Expand All @@ -36,19 +36,21 @@ Parental gene
The **gene** which **underwent retrotransposition** process,
giving rise to the retrocopy.

Host gene
It may happen that the retrotransposition occurs **inside**
another gene - which in turn is called the **host** gene
for this retrocopy.

Genomic position
The genome **coordinate** where occured the retrocopy
**integration** (chromosome:start-end). It includes the
**insertion point**.

Strandness
Detects the **strand** (+/-), taking into account the
orientation in relation to the parental gene.
Detects the orientation of the insertion (+/-). It takes into
account the orientation of insertion, whether in the
**leading** (+) or **lagging** (-) DNA strand.

Genomic context
The retrocopy integration site context: If the retrotransposition
event occurred at an **intergenic** or **intragenic** region - the
latter can be splitted into **exonic** and **intronic** according
to the host gene.

Genotype
When **multiple** individuals are analysed, annotate the
Expand All @@ -57,7 +59,8 @@ Genotype
among the cohort.

Haplotype
If the event occured in one or both **homologous chromosomes**
Our tool provides information about the ploidy of the event,
i.e., whether it occurs in one or both **homologous** chromosomes
(homozygous or heterozygous).

How it works
Expand Down

0 comments on commit e4127fe

Please sign in to comment.