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ntr tRNA 2'-O-methyltransferase #13185

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ValWood opened this issue Mar 16, 2017 · 8 comments
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ntr tRNA 2'-O-methyltransferase #13185

ValWood opened this issue Mar 16, 2017 · 8 comments

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@ValWood
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ValWood commented Mar 16, 2017

I could only find
tRNA (guanosine-2'-O-)-methyltransferase activity

child of
GO:0008171 O-methyltransferase activity
GO:0008175 tRNA methyltransferase activity

http://www.yeastgenome.org/reference/S000120470/overview
(I'm annotating the ortholog)

@ValWood
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ValWood commented Mar 16, 2017

would use for Trm7 too,
http://www.yeastgenome.org/locus/S000000265/overview

@hdrabkin
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hdrabkin commented Mar 16, 2017

I know there is 2'-O-methylcytidine (Cm), as well as Um, and Am, but not sure at the moment if there are individual proteins responsible. Hope to find what I'm looking for here: Front. Genet., 23 May 2014 | https://doi.org/10.3389/fgene.2014.00144
http://journal.frontiersin.org/article/10.3389/fgene.2014.00144/full
Note both nucleobase and sugar can be methylated.

fgene-05-00144-g001

@hdrabkin
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Done

@ValWood
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ValWood commented Aug 14, 2017

Thanks Harold.

tRNA (guanosine-2'-O-)-methyltransferase activity
should be a descendant of tRNA 2'-O-methyltransferase GO:0106050?

@ValWood ValWood reopened this Aug 14, 2017
@hdrabkin
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hdrabkin commented Aug 16, 2017

Yes; should be;
I am having trouble because of the 'prime in the title using Protege and hope to have it sorted out during the workshop.

@ukemi
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ukemi commented Aug 16, 2017

tRNA 2'-O-methyltransferase should work.

@ukemi
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ukemi commented Aug 16, 2017

Argh add a backslash before the prime.

@hdrabkin
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keeping this PG
done

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