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layout id title type fail_mode status contact implementations
rule
GORULE:0000025
Creating more specific annotations by reasoning over extensions
report
soft
proposed
cjmungall@lbl.gov

Given an annotation to a general term plus annotation extensions we can infer a more specific annotation.

For example, given a source annotation:

Gene = geneA
Annotation_class = GO:0006260 ! DNA replication
Annotation_extension = {occurs_in GO:0000262 ! mitochondrial chromosome}

This will be inferred:

Gene = geneA
Annotation_class = GO:0006264 ! mitochondrial DNA replication
Annotation_extension = {occurs_in GO:0000262 ! mitochondrial chromosome}
Evidence: IC
With: GO:0006260

Approach is described in more detail here: https://github.com/owlcollab/owltools/wiki/Annotation-Extension-Folding

Fields:

  • GO ID: new inferred, more specific GO ID
  • Evidence: IC
  • With: original GO ID
  • Assigned-by: GOC-OWL

Other fields remain the same