Systems immunology based drug-repurposing framework to target inflammation in atherosclerosis

This repository contains the code for the data analysis in: "Systems immunology-based drug repurposing framework to target inflammation in atherosclerosis" https://www.nature.com/articles/s44161-023-00278-y

Raw Data

Bulk-RNAseq

Raw data and processed count matrices for this study have been deposited in GEO under the accession number GSE230217 https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE230217

CYTOF rawdata

CYTOF FCS files can be retrieved from the link https://zenodo.org/record/7851084#.ZEKbC-zMJB0

Enrichr

Enrichr version 3.0 was used to do the pathway analysis

Contributions

The Code for this manuscript was generated by Simon Koplev https://github.com/skoplev and Ravneet Kaur https://github.com/kravneet