QTLnetwork

Prioritize candidate genes by random walks on molecular networks

Code accompanying the manuscript: Genetic variation influencing DNA methylation provides new insights into the molecular pathways regulating genomic function.

Johann S Hawe, Rory Wilson, Katharina Schmid, Li Zhou, Lakshmi Lakshmanan, Benjamin C Lehne, Brigitte Kühnel, William R Scott, Matthias Wielscher, Yik Weng Yew, Clemens Baumbach, Dominic P Lee, Eirini Marouli, Manon Bernard, Liliane Pfeiffer, Pamela Matías-García, Matias I Autio, Stephane Bourgeois, Christian Herder, Ville Karhunen, Thomas Meitinger, Holger Prokisch, Wolfgang Rathmann, Michael Roden, Sylvain Sebert, Jean Shin, Konstantin Strauch, Weihua Zhang, Wilson LW Tan, Stefanie M. Hauck, Juliane Merl-Pham, Harald Grallert, Eudes GV Barbosa, MuTHER Consortium, Thomas Illig, Annette Peters, Tomas Paus, Zdenka Pausova, Panos Deloukas, Roger SY Foo, Marjo-Riitta Jarvelin, Jaspal S Kooner, Marie Loh, Matthias Heinig, Christian Gieger, Melanie Waldenberger, and John C Chambers.

Installation

You will need the latest version of devtools. First install the release version:

install.packages("devtools")

then update it to the latest developement version:

devtools::install_github("hadley/devtools")

Finally you can install the latest development version of QTLnetwork from github with:

devtools::install_github("matthiasheinig/QTLnetwork")