Title: Identification of pre-exhaustion CD8+ T cell subpopulation and core genes as key role in T cell exhaustion by dynamic network biomarker

Materials and methods

trajectory Analysis Files

1 MONOCLE_TTC_V1.R

Data Processing Files

1 TTC_Seurat_SingleR.R

DNB genes list by SCE method

1 DNB_genes_list.txt

Identification of pre-exhaustion T cell subpopulation

1 DEseq2_mfuzz.R

functional enrichment analysis

1 ClueGOResultTable.xls 2 GSVA_ES.csv 3 GSVA_DEG.R

iTalker files

1 LRpairs_Overview_checkpoint.csv LRpairs_Overview_cytokine.csv LRpairs_Overview_growth factor.csv LRpairs_Overview_other.csv 2 iTALK.R