repository with code to perform analysis of t1d and t2d overlap analysis
Refer to the following READMEs for guidance on the running order for each part of the analysis.
./t1d_analysis/setup/README.md
Analysis set up.
./t1d_analysis/meta-analysis/README.md
Peforms the association analysis and meta-analysis across collections, including UK and Sardinian cohort.
./t1d_analysis/conditional/README.md
Performs conditional analyses for all T1D FDR<0.01 associated regions
Summary stats used (unadjusted for BMI) from Mahajan et. al, Nature Genetics 2018 doi: 10.1038/s41588-018-0241-6
./t1d_t2d_colocalisation/README.md
Identifies regions of overlap (FDR <0.01 to both diseases) and examines colocalisations between diseases in those regions.