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National Estimates of the Adult Diabetes Care Continuum in India, 2019-2021

Publication

The publication in JAMA Internal Medicine.

Dashboard

The dashboard may take some time to load and can be accessed here: EGDRC India Diabetes Care Cascade

Abstract

Importance

Diabetes mellitus (DM) is widespread and treatable. Little is known about the diabetes care continuum (diagnosis, treatment, and control) in India, and whether it varies at the national, state, and district levels.

Objective

To estimate the diabetes care continuum among individuals aged 18-98 years old at national, state, and district-levels, and by socio-demographic group.

Design

Cross-sectional, nationally-representative survey, 2019-

Setting

28 states, 8 union territories, and 707 districts of India

Participants

1,895,287 approached in the Fifth National Family Health Survey (NFHS-5)

Exposures

District, state, urban vs rural residence, age (18-39, 40-64, ≥65 years), sex, household wealth quintile

Main Outcomes and Measures

Diabetes was defined by self-report or high capillary blood glucose (≥126mg/dL [fasting] or ≥220mg/dL [non-fasting]). Among respondents who had previously been diagnosed with diabetes, we reported the proportions treated (self-reported medication use) and proportion controlled (blood glucose <126 [fasting] or ≤180 mg/dL [non-fasting]). We benchmarked findings against the World Health Organization’s Global Diabetes Compact Targets (80% diagnosis, 80% control among those diagnosed). We partitioned the variance in indicators between and within states using variance partition coefficients (VPC

Results

Among 1,651,176 adult respondents (52.6% female; mean age: 41.6 years) with blood glucose measures, the proportion with diabetes was 6.5% [95%CI: 6.4, 6.6]. Among adults with diabetes, 74.2% [73.3, 75.0] were diagnosed. Among those diagnosed, 59.4% [58.1, 60.6] reported taking medication and 65.5% [64.5, 66.4] achieved control. Diagnosis and treatment were higher in urban areas, older age groups, and wealthier households. Of the 707 districts, 34.8% districts met the diagnosis target, while 10.7% districts met the control target among those diagnosed. Most of the variability in diabetes diagnosis (VPC:89.1%), treatment (VPC:85.9%), and control (VPC:95.6%) were within-state, and not between states.

Conclusions and Relevance

Nationally, India’s diabetes care continuum masks considerable state- and district-level variation, as well as age- and rural-urban disparities. Surveillance at the district-level can guide state health administrators to prioritize interventions and monitor achievement of global targets.

Comparison with previous studies

Study Name Years doi Study Population Diabetes (%) Diagnosed/Aware (%) Treated (%) Controlled (%)
Unnikrishnan 2014 INDIAB Phase 1 2008-10 10.1089/dia.2014.0018 20+ y; n = 14227 - - - 31%
Prenissl 2019 NFHS 2015-16 10.1186/s12916-019-1325-6 15-49y; n = 729829 3.3% 52.5% 40.5% 24.8%
Mathur 2022 NNMS 2017-18 10.3389/fpubh.2022.748157 18-69y; n = 9721 9.3% 45.8% 36.1% 15.7%
Flood 2022 LASI 2017-18 10.2139/ssrn.4066713 45+ y; n = 56995 19.7% 60.4% - 46.1%
Anjana 2021 INDIAB 2008-20 10.1016/S2213-8587(22)00072-9 20+ y; n = 113043 - - - 36.3%
Current Study NFHS-5 2019-21 - 18+ y; n = 1651176 6.5% 70.1% 59.4% 34.5%

Comparison with NNMS 2017-18

The prevalence of diagnosed population in total population is 4.3% (9.3% $\times$ 45.8%) in NNMS and 4.3% (5.9% $\times$ 72.3%) in NFHS-5 for the same study population.

Study Name Years doi Study Population Diabetes (%) Diagnosed/Aware (%) Treated (%) Controlled (%)
Mathur 2022 NNMS 2017-18 10.3389/fpubh.2022.748157 18-69y; n = 9721 9.3% 45.8% 36.1% 15.7%
Current Study NFHS-5 2019-21 - 18-69y; n = 1552032 5.9% 72.3% 50.1% 28.0%

Comparison with LASI 2017-18

The prevalence of diagnosed population in total population is 11.9% (19.7% $\times$ 60.4%) in LASI and 9.1% (12.1% $\times$ 75.5%) in NFHS-5 for the same study population.

Study Name Years doi Study Population Diabetes (%) Diagnosed/Aware (%) Treated (%) Controlled (%)
Flood 2022 LASI 2017-18 10.2139/ssrn.4066713 45+ y; n = 56995 19.7% 60.4% - 46.1%
Current Study NFHS-5 2019-21 - 45+ y; n = 668099 12.1% 75.5% 58.3% 33.6%

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NFHS Diabetes Care Cascade, 2019-21

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