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R package to identify genes with differential distributions in single-cell RNA-seq
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scDD: An R package to identify differentially distributed genes in scRNA-seq


The Bioconductor landing page is To install, make sure you have the current version of Bioconductor, and use the following commands:


Quick Start

For examples and tips on using the package, please see the vignette PDF here which you can alternatively bring up by typing


after installing and loading the package into R.

Getting Help

Please send bug reports and feature requests by sending a message to Bioconductor Support at or by opening a new issue on this page


Please cite the following publication if you use scDD in your work:

Korthauer KD, Chu LF, Newton MA, Li Y, Thomson J, Stewart R, Kendziorski C. A statistical approach for identifying differential distributions in single-cell RNA-seq experiments. Genome Biology. 2016 Oct 25;17(1):222.

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