Evolution of protein interactomes across the tree of life

Author: Marinka Zitnik (marinka@cs.stanford.edu)

Paper: Evolution of resilience in protein interactomes across the tree of life

Project website

Overview: How does Darwinian evolution change molecular networks?

Large-scale protein interactome data reveal how protein-protein interaction networks change through evolution and how changes in these networks impact phenotypes and organismal response to environmental fluctuations.

Citing

If you find this work useful for your research, please consider citing this paper:

@article{Zitnik2019,
  title     = {Evolution of resilience in protein interactomes across the tree of life},
  author    = {Zitnik, Marinka and Sosic, Rok and Feldman, Marcus W. and Leskovec, Jure},
  journal   = {Proceedings of the National Academy of Sciences}
  volume    = {116},
  number    = {10},
  pages     = {4426--4433},
  year      = {2019},
  doi       = {10.1073/pnas.1818013116},
  publisher = {National Academy of Sciences}
}

Miscellaneous

Please send any questions you might have about the code and/or algorithms to marinka@cs.stanford.edu.

License

The code is licensed under the MIT License.